•A processed-foods diet (PD) impaired learning and memory in aged male rats. •PD increased inflammatory genes in the hippocampus and amygdala of aged rats. •DHA supplementation prevented memory deficits in PD-fed aged rats. •DHA supplementation ameliorated increases in inflammatory gene expression. •PD consumption led to increased weight gain in young and aged rats. AbstractThe consumption… Continue reading Dietary #DHA prevents cognitive impairment and inflammatory gene expression in aged male rats fed a diet enriched with refined #carbohydrates
Tag: Cognitive Impairment
#Depressive Symptoms Imputed Across the Life Course Are Associated with #Cognitive Impairment and Cognitive Decline
Depressive symptoms may increase risk for dementia, but findings are controversial because late-life depression may be a prodromal dementia symptom. Life course data on depression and dementia risk may clarify this association; however, data is limited. Objective: To impute adult depressive symptoms trajectories across adult life stages and estimate the association with cognitive impairment and… Continue reading #Depressive Symptoms Imputed Across the Life Course Are Associated with #Cognitive Impairment and Cognitive Decline
Long-term Dietary #Flavonoid Intake and Subjective #Cognitive Decline in US Men and Women
To prospectively examine the associations between long-term dietary flavonoids and subjective cognitive decline (SCD). Methods: We followed 49,493 women from the Nurses’ Health Study (NHS) (1984-2006) and 27,842 men from the Health Professionals Follow-up Study (HPFS) (1986-2002). Poisson regression was used to evaluate the associations between dietary flavonoids (flavonols, flavones, flavanones, flavan-3-ols, anthocyanins, polymeric flavonoids,… Continue reading Long-term Dietary #Flavonoid Intake and Subjective #Cognitive Decline in US Men and Women
Dose-Response Meta-Analysis on #Tooth Loss With the Risk of #Cognitive Impairment and #Dementia
To quantify the dose-response associations between tooth loss and risk of cognitive impairment and dementia. DesignLongitudinal studies that examined the association between tooth loss and cognitive function were systematically searched on 6 databases through March 1, 2020. The study adhered to Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) reporting guidelines. Risk estimates were… Continue reading Dose-Response Meta-Analysis on #Tooth Loss With the Risk of #Cognitive Impairment and #Dementia
Effects of #music participation for mild #cognitive impairment and #dementia: A systematic review and meta-analysis
To examine randomized controlled trials with active music-making interventions, in which older adults with probable mild cognitive impairment (MCI) or dementia physically participate in music, and their effects on cognitive functioning, emotional well-being, and social engagement. Participating in music-making is engaging and has shown diverse benefits. Additionally, this review categorized the music activities of each… Continue reading Effects of #music participation for mild #cognitive impairment and #dementia: A systematic review and meta-analysis
The efficacy of #exergaming in people with major #neurocognitive disorder residing in long-term care facilities: a pilot randomized controlled trial
It is currently unknown whether exergaming is efficacious in people with major neurocognitive disorder (MNCD) residing in long-term care facilities. This pilot randomized controlled trial (RCT) explored the efficacy of a stepping exergame program on gait speed, balance, mobility, reaction time, cognitive and neuropsychiatric outcomes, quality of life, and daily life functioning in people with… Continue reading The efficacy of #exergaming in people with major #neurocognitive disorder residing in long-term care facilities: a pilot randomized controlled trial
Association between self‐reported night #sleep duration and #cognitive function among older adults with intact global cognition
The purpose of this study was to clarify the association between self‐reported night sleep duration and cognitive functions such as word memory, story memory, attention, executive function, and processing speed of older adults with normal global cognitive function. Methods A total of 241 functionally independent older adults (mean age, 75.5 ± 6.4 years) participated in… Continue reading Association between self‐reported night #sleep duration and #cognitive function among older adults with intact global cognition
Changes in Body #Mass Index Are Related to Faster #Cognitive Decline Among African American Older Adults
The purpose of this study was to: (1) examine relationships between body mass index (BMI) stability and cognitive decline in older African Americans; and (2) investigate differences in the relationships between women and men.. ..Participants (n = 671; mean age = 73.5 years; standard deviation = 6.2 years) were included in the present analysis if they were… Continue reading Changes in Body #Mass Index Are Related to Faster #Cognitive Decline Among African American Older Adults
#Cognitive decline in older adults with #epilepsy: The Cardiovascular Health Study
Cognitive decline is a major concern for older adults with epilepsy. Whether and how much faster older adults with epilepsy experience cognitive decline beyond expected age‐related cognitive change remain unclear. We sought to estimate and compare rates of cognitive decline in older adults with and without epilepsy.. ..The rate of decline in 3MS was significantly… Continue reading #Cognitive decline in older adults with #epilepsy: The Cardiovascular Health Study
2 Medical News 