Background and ObjectivesVascular theories of cognitive aging have focused on macrovascular changes and cognitive decline. However, according to the artery-size hypothesis, microvascular changes, such as those that underlie changes in erectile function, may also play an important role in contributing to cognitive decline. Thus, we examined associations between erectile function, sexual satisfaction, and cognition starting… Continue reading Erectile Function, Sexual Satisfaction, and Cognitive Decline in Men From Midlife to Older Adulthood
Tag: Cognitive Impairment
Effects of Tai Chi Chuan on Cognitive Function in Adults 60 Years or Older With Type 2 Diabetes and Mild Cognitive Impairment in ChinaA Randomized Clinical Trial
Importance Type 2 diabetes (T2D) is associated with the progression of cognitive dysfunction. Physical activity benefits cognition, but no evidence from randomized clinical trials has shown whether tai chi chuan has better long-term benefits than fitness walking in cognitive function for patients with T2D and mild cognitive impairment (MCI).Objective To compare the effectiveness of tai… Continue reading Effects of Tai Chi Chuan on Cognitive Function in Adults 60 Years or Older With Type 2 Diabetes and Mild Cognitive Impairment in ChinaA Randomized Clinical Trial
Genetic analyses identify brain structures related to cognitive impairment associated with elevated blood pressure
Background and aimsObservational studies have linked elevated blood pressure (BP) to impaired cognitive function. However, the functional and structural changes in the brain that mediate the relationship between BP elevation and cognitive impairment remain unknown. Using observational and genetic data from large consortia, this study aimed to identify brain structures potentially associated with BP values… Continue reading Genetic analyses identify brain structures related to cognitive impairment associated with elevated blood pressure
Periodontal health, cognitive decline, and dementia: A systematic review and meta-analysis of longitudinal studies
AbstractBackgroundEmerging evidence indicates that poor periodontal health adversely impacts cognition. This review examined the available longitudinal evidence concerning the effect of poor periodontal health on cognitive decline and dementia.MethodsComprehensive literature search was conducted on five electronic databases for relevant studies published until April 2022. Longitudinal studies having periodontal health as exposure and cognitive decline and/or… Continue reading Periodontal health, cognitive decline, and dementia: A systematic review and meta-analysis of longitudinal studies
Single-Channel EEG Features Reveal an Association With Cognitive Decline in Seniors Performing Auditory Cognitive Assessment
Background: Cognitive decline remains highly underdiagnosed despite efforts to find novel cognitive biomarkers. Electroencephalography (EEG) features based on machine-learning (ML) may offer a non-invasive, low-cost approach for identifying cognitive decline. However, most studies use cumbersome multi-electrode systems. This study aims to evaluate the ability to assess cognitive states using machine learning (ML)-based EEG features extracted from… Continue reading Single-Channel EEG Features Reveal an Association With Cognitive Decline in Seniors Performing Auditory Cognitive Assessment
Longitudinal associations of childhood fitness and obesity profiles with midlife cognitive function: an Australian cohort study
ObjectivesClusters of low fitness and high obesity in childhood are associated with poorer health outcomes in later life, however their relationship with cognition is unknown. Identifying such profiles may inform strategies to reduce risk of cognitive decline. This study examined whether specific profiles of childhood fitness and obesity were associated with midlife cognition. DesignProspective study.… Continue reading Longitudinal associations of childhood fitness and obesity profiles with midlife cognitive function: an Australian cohort study
Time Trends in Incidence of Reported Memory Concerns and Cognitive Decline: A Cohort Study in UK Primary Care
Purpose: To investigate time trends in incidence of recorded memory concerns (MC) and cognitive decline (CD) in a UK older population presenting to primary care with no prior diagnosis of dementia. To determine the risk of developing dementia in people with recorded memory concern and cognitive decline.Patients and methods: We included individuals aged 65– 99… Continue reading Time Trends in Incidence of Reported Memory Concerns and Cognitive Decline: A Cohort Study in UK Primary Care
Amateur Boxing and DementiaCognitive Impairment Within the 35-Year Caerphilly Cohort Study
Objective:To examine the long-term effects of amateur boxing in a representative population sample of men. Design:The sample was examined every 5 years for 35 years. Cognition was assessed repeatedly from the third examination. Previous boxing experience and dementia were assessed at the fifth examination, and dementia assessed subsequently through medical records. Setting and Assessment of… Continue reading Amateur Boxing and DementiaCognitive Impairment Within the 35-Year Caerphilly Cohort Study
Role of Adipocyte Na,K-ATPase Oxidant Amplification Loop in #Cognitive Decline and #Neurodegeneration
•Adipocytes induce phenotypical changes in neurodegeneration through adipocyte NKAL.•Adipocyte specific NaKtide inhibited NKAL and improved systemic homeostasis.•NaKtide improved adipocyte phenotype and improved markers of neurodegeneration.•NaKtide improved genomic profile of hippocampus and adipose tissue in WD fed mice. SummaryRecent studies suggest that a western diet may contribute to clinical neurodegeneration and dementia. Adipocyte-specific expression of the… Continue reading Role of Adipocyte Na,K-ATPase Oxidant Amplification Loop in #Cognitive Decline and #Neurodegeneration
2 Medical News 