Maternal #Obesity and Risk of Sudden Unexpected Infant Death

Importance  Rates of maternal obesity are increasing in the US. Although obesity is a well-documented risk factor for numerous poor pregnancy outcomes, it is not currently a recognized risk factor for sudden unexpected infant death (SUID).Objective  To determine whether maternal obesity is a risk factor for SUID and the proportion of SUID cases attributable to maternal obesity.Design,… Continue reading Maternal #Obesity and Risk of Sudden Unexpected Infant Death

The effect of #anxiety on all-cause #dementia: A longitudinal analysis from the Hunter Community Study

BackgroundAnxiety is common, however, the effect of chronicity of anxiety on dementia has not been explored. This study aims to assess the longitudinal relationship between chronic versus resolved versus new onset anxiety, and all-cause dementia risk.MethodsA total of 2132 participants with mean age 76 years from the Hunter Community Study were recruited. Anxiety was measured using… Continue reading The effect of #anxiety on all-cause #dementia: A longitudinal analysis from the Hunter Community Study

#Tattoos as a risk factor for malignant #lymphoma: a population-based case–control study

BackgroundThe popularity of tattoos has increased dramatically over the last few decades. Tattoo ink often contains carcinogenic chemicals, e.g., primary aromatic amines, polycyclic aromatic hydrocarbons, and metals. The tattooing process invokes an immunologic response that causes translocation of tattoo ink from the injection site. Deposition of tattoo pigment in lymph nodes has been confirmed but the long-term… Continue reading #Tattoos as a risk factor for malignant #lymphoma: a population-based case–control study

Recipe for Heart Health: A Randomized Crossover Trial on Cardiometabolic Effects of Extra Virgin #Olive #Oil Within a Whole‐Food Plant‐Based Vegan #Diet

Whole‐food, plant‐based vegan diets, low in oils, and Mediterranean diets, rich in extra virgin olive oil (EVOO), reduce cardiovascular disease risk factors. Optimal quantity of dietary fat, particularly EVOO, is unclear.Methods and ResultsIn a randomized crossover trial with weekly cooking classes, adults with ≥5% cardiovascular disease risk followed a high (4 tablespoons/day) to low (<1 teaspoon/day)… Continue reading Recipe for Heart Health: A Randomized Crossover Trial on Cardiometabolic Effects of Extra Virgin #Olive #Oil Within a Whole‐Food Plant‐Based Vegan #Diet

Energy Intake and Dietary Glycemic Load in Late Morning and Risk of Type 2 #Diabetes: The Hispanic Community #Health Study/Study of #Latinos, a Multicenter Prospective Cohort Study

To evaluate the association between meal timing and type 2 diabetes risk in U.S. Hispanic/Latino adults.RESEARCH DESIGN AND METHODSThe Hispanic Community Health Study/Study of Latinos (HCHS/SOL) is a multicenter, community-based, prospective cohort study. This study included 8,868 HCHS/SOL adults without diabetes at baseline (2008–2011) and attending the visit 2 examination (2014–2017). Energy intake and glycemic… Continue reading Energy Intake and Dietary Glycemic Load in Late Morning and Risk of Type 2 #Diabetes: The Hispanic Community #Health Study/Study of #Latinos, a Multicenter Prospective Cohort Study

Glycated Hemoglobin A1c Time in Range and #Dementia in Older Adults With #Diabetes

Key PointsQuestion  In older individuals with diabetes, is maintaining stability of glycated hemoglobin A1c levels (HbA1c) in individualized target ranges over time associated with lower risk of Alzheimer disease and related dementias (ADRD)?Findings  In this cohort study of 374 021 older veterans with diabetes, greater HbA1c stability, as measured by HbA1c time in range, was associated with a lower risk of… Continue reading Glycated Hemoglobin A1c Time in Range and #Dementia in Older Adults With #Diabetes

Bilateral #Mastectomy and #Breast Cancer Mortality

Question  Does bilateral mastectomy for treatment of unilateral breast cancer reduce the 20-year risk of breast cancer mortality?Findings  This cohort study including 661 270 women with unilateral breast cancer who were closely matched by treatment type (lumpectomy, unilateral mastectomy, or bilateral mastectomy) and followed up for 20 years found that bilateral mastectomy was associated with a statistically significant… Continue reading Bilateral #Mastectomy and #Breast Cancer Mortality

Are Blood Tests for #Alzheimer Disease Ready for Prime Time?

This is a transformative time for patients with Alzheimer disease. Alzheimer disease is increasingly viewed as a treatable condition and managed like other major chronic diseases, such as heart disease and cancer. Management of Alzheimer disease includes early diagnosis with molecular confirmation, disease-modifying treatments that are initiated early in the disease course, better risk reduction… Continue reading Are Blood Tests for #Alzheimer Disease Ready for Prime Time?

The predictive validity of a #Brain Care Score for late-life #depression and a composite outcome of #dementia, #stroke, and late-life #depression: data from the UK Biobank cohort

Introduction: The 21-point Brain Care Score (BCS) is a novel tool designed to motivate individuals and care providers to take action to reduce the risk of stroke and dementia by encouraging lifestyle changes. Given that late-life depression is increasingly recognized to share risk factors with stroke and dementia, and is an important clinical endpoint for brain… Continue reading The predictive validity of a #Brain Care Score for late-life #depression and a composite outcome of #dementia, #stroke, and late-life #depression: data from the UK Biobank cohort