Day-to-day associations between #testosterone, #sexual desire and #courtship efforts in young men

Testosterone plays important roles in reproductive behaviour in many species. Despite a common belief that testosterone regulates fluctuations in human sexual desire, there is little direct evidence that relates within-person changes in natural testosterone production to within-person changes in sexual desire. Here, we measured daily salivary testosterone concentrations from 41 adult men for one month,… Continue reading Day-to-day associations between #testosterone, #sexual desire and #courtship efforts in young men

#LEVOTHYROXINE USE AND #BONE LOSS IN #EUTHYROID #OLDER ADULTS: A LONGITUDINAL ANALYSIS FROM BALTIMORE LONGITUDINAL STUDY OF AGING | S3B-SPMS-1

Purpose: Levothyroxine (LT4) is the second most commonly prescribed medication in older adults. Frank hyperthyroidism accelerates bone turnover and even subclinical hyperthyroid has been associated with increased fracture risk. Data indicates that a significant proportion of thyroid hormone prescriptions may be given to older adults without hypothyroidism raising concerns about subsequent relative excess of thyroid… Continue reading #LEVOTHYROXINE USE AND #BONE LOSS IN #EUTHYROID #OLDER ADULTS: A LONGITUDINAL ANALYSIS FROM BALTIMORE LONGITUDINAL STUDY OF AGING | S3B-SPMS-1

Effects of #Kinesio tape on individuals with #carpal tunnel syndrome: a randomized controlled study

Objective: Carpal tunnel syndrome (CTS) is a common neuromuscular disorder with an incidence rate of 4.9%. Research on the impact of Kinesio taping (KT) on electroneurography in individuals with CTS is limited, highlighting a significant gap in the literature. This study aimed to evaluate the effects of KT on palm numbness, pain intensity, hand grip… Continue reading Effects of #Kinesio tape on individuals with #carpal tunnel syndrome: a randomized controlled study

Parent-child #relationship quality predicts higher subjective #well-being in adulthood across a diverse group of countries

Theoretically and empirically, parenting is closely related to the psychological health of offspring, but long-term effects and possible international differences are not well established. In a pre-registered multilevel modeling analysis using data from the Global Flourishing Study, we tested whether retrospective parent-child relationship quality predicts adult well-being in a representative sample of 202,898 adults living… Continue reading Parent-child #relationship quality predicts higher subjective #well-being in adulthood across a diverse group of countries

#Cardiovascular risk and #obesity impact loss of grey matter volume earlier in males than females

Background It remains imperative to discover the time course that cardiovascular risk factors influence neurodegeneration in males and females and decipher whether the apolipoprotein (APOE) genotype mediates this relationship. Here we perform a large-scale evaluation of the influence of cardiovascular risk and obesity on brain volume in males and females in different age groups.Methods 34… Continue reading #Cardiovascular risk and #obesity impact loss of grey matter volume earlier in males than females

A new era in the treatment of acute exacerbations of #asthma and #COPD

Nearly 4 million patients with chronic obstructive pulmonary disease (COPD) or asthma die each year, mostly from severe acute exacerbations.1 For the past 60 years, systemic corticosteroids have been the mainstay treatment of acute exacerbations.2 However, they confer only modest beneficial effects and are fraught with many adverse health effects including adrenal insufficiency, osteoporosis, and… Continue reading A new era in the treatment of acute exacerbations of #asthma and #COPD

Applied body-fluid analysis by #wearable devices

Wearable sensors are a recent paradigm in healthcare, enabling continuous, decentralized, and non- or minimally invasive monitoring of health and disease. Continuous measurements yield information-rich time series of physiological data that are holistic and clinically meaningful. Although most wearable sensors were initially restricted to biophysical measurements, the next generation of wearable devices is now emerging… Continue reading Applied body-fluid analysis by #wearable devices

#Physical activity and life #expectancy: a life-table analysis

Objective Low physical activity (PA) levels are associated with increased mortality. Improved measurement has resulted in stronger proven associations between PA and mortality, but this has not yet translated to improved estimates of the disease burden attributable to low PA. This study estimated how much low PA reduces life expectancy, and how much life expectancy… Continue reading #Physical activity and life #expectancy: a life-table analysis

#Coffee consumption is associated with intestinal #Lawsonibacter asaccharolyticus abundance and prevalence across multiple cohorts

Although diet is a substantial determinant of the human gut microbiome, the interplay between specific foods and microbial community structure remains poorly understood. Coffee is a habitually consumed beverage with established metabolic and health benefits. We previously found that coffee is, among >150 items, the food showing the highest correlation with microbiome components. Here we… Continue reading #Coffee consumption is associated with intestinal #Lawsonibacter asaccharolyticus abundance and prevalence across multiple cohorts