..The hypothyroid symptoms score decreased from 21.7 at baseline to 19.3 at 12 months in the levothyroxine group vs from 19.8 at baseline to 17.4 at 12 months in the placebo group (adjusted between-group difference, 1.3 [95% CI, −2.7 to 5.2]; P = .53). The tiredness score increased from 25.5 at baseline to 28.2 at 12 months… Continue reading Association Between #Levothyroxine Treatment and Thyroid-Related Symptoms Among Adults Aged 80 Years and Older With Subclinical #Hypothyroidism
Is #running associated with a lower risk of all-cause, #cardiovascular and cancer #mortality, and is the more the better? A systematic review and meta-analysis
Fourteen studies from six prospective cohorts with a pooled sample of 232 149 participants were included. In total, 25 951 deaths were recorded during 5.5–35 year follow-ups. Our meta-analysis showed that running participation is associated with 27%, 30% and 23% lower risk of all-cause (pooled adjusted hazard ratio (HR)=0.73; 95% confidence interval (CI) 0.68 to 0.79), cardiovascular (HR=0.70;… Continue reading Is #running associated with a lower risk of all-cause, #cardiovascular and cancer #mortality, and is the more the better? A systematic review and meta-analysis
Does chronic high-intensity #endurance training have an effect on cardiovascular markers of active populations and athletes? Systematic review and meta-analysis
There was significant improvement in high-density #lipoprotein with weighted standardised mean difference and effect size=−1.06 (−1.83 to −0.30), p=0.006. We have also observed a significant reduction in low-density lipoprotein and total cholesterol with weighted standardised mean difference and effect size=−0.97 (−1.58 to −0.36), p=0.002, and = −0.78 (−1.34 to −0.22), p=0.007, respectively. There was a… Continue reading Does chronic high-intensity #endurance training have an effect on cardiovascular markers of active populations and athletes? Systematic review and meta-analysis
Relationship between #obesity indices and #hypertension among middle-aged and elderly populations in Taiwan: A community-based, cross-sectional study
..The obesity indices included body mass index (BMI), body fat (BF) percentage and waist circumference (WC). Of the 396 people recruited, 200 had HTN. The age-adjusted Pearson’s coefficients of BMI, BF percentage and WC were 0.23 (p<0.001), 0.14 (p=0.01) and 0.26 (p<0.001), respectively. Multiple logistic regression of the HTN-related obesity indices showed that the ORs… Continue reading Relationship between #obesity indices and #hypertension among middle-aged and elderly populations in Taiwan: A community-based, cross-sectional study
How the #weather affects the #pain of citizen scientists using a smartphone app
Weather has been thought to affect symptoms in patients with chronic disease since the time of Hippocrates over 2000 years ago. Around three-quarters of people living with arthritis believe their pain is affected by the weather.. ..Precipitation was not associated with an increased odds of a pain event (OR 0.996 (0.989–1.003) per 1 mm daily rainfall… Continue reading How the #weather affects the #pain of citizen scientists using a smartphone app
Intact global #cognitive and #olfactory ability predicts lack of transition to #dementia
Odor identification deficits characterize Alzheimer's disease and other dementias ..Smell Identification Test, which includes the 12-item Brief Smell Identification Test (B-SIT) ..In covariate-adjusted survival analyses, impairment on the Blessed Orientation Memory Concentration Test and B-SIT each predicted dementia (n = 109), primarily Alzheimer's disease (n = 101). Among participants with intact olfactory (B-SIT ≥ 11/12… Continue reading Intact global #cognitive and #olfactory ability predicts lack of transition to #dementia
A Randomized Controlled Trial of #Metacognitive Therapy for #Depression: Analysis of 1-Year Follow-Up
..low mood and depression is prolonged by perseverative thinking styles, such as depressive rumination, worry, and other unhelpful self-regulation strategies. This thinking style, called the cognitive attentional syndrome (CAS; Wells and Matthews, 1994) is influenced by positive and negative metacognitive beliefs about uncontrollability and danger of rumination and worry as well as maladaptive executive control… Continue reading A Randomized Controlled Trial of #Metacognitive Therapy for #Depression: Analysis of 1-Year Follow-Up
Effect of different #nap opportunity durations on short-term maximal performance, attention, feelings, muscle soreness, fatigue, #stress and sleep.
The aim of the present study was to determine the effect of different nap opportunity durations on short-term maximal performance, attention, feelings, muscle soreness, fatigue, stress and sleep. Twenty physically active men (age: 21.1 ± 3.6 years, height: 176.4 ± 5.7 cm, body-mass: 72 ± 10.8 kg) performed the 5-jump and the digit-cancellation (i.e., attention) tests after four randomized nap opportunity conditions: no-nap opportunity… Continue reading Effect of different #nap opportunity durations on short-term maximal performance, attention, feelings, muscle soreness, fatigue, #stress and sleep.
#Alcohol Consumption and Risk of Liver #Cirrhosis A Systematic Review and Meta-Analysis
..There was no increased risk for occasional drinkers. Consumption of one drink per day in comparison to long-term abstainers showed an increased risk for liver cirrhosis in women, but not in men. The risk for women was consistently higher compared to men. Drinking ≥5 drinks per day was associated with a substantially increased risk in… Continue reading #Alcohol Consumption and Risk of Liver #Cirrhosis A Systematic Review and Meta-Analysis
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