Associations between affective problems (anxiety and depression) and premature mortality have been demonstrated among psychiatric, medical, and community-based samples and across many causes of death.. ..Of 3001 study members (1509 [50.3%] female, 1492 [49.7%] male), 235 individuals (7.8%) died over a 15-year follow-up. After adjustment for sex, those who experienced case-level affective symptoms 1, 2,… Continue reading Association Between Lifetime Affective Symptoms and Premature Mortality
Association Between #Celiac Disease and Mortality Risk in a Swedish Population
There were 49 829 patients with celiac disease, including 24% who were diagnosed between the years 2010 and 2017. The mean (SD) age at diagnosis was 32.2 (25.2) years and 62.4% were women. During a median follow-up time of 12.5 years, 13.2% (n = 6596) died. Compared with controls (n = 246 426), overall mortality was increased in those with celiac… Continue reading Association Between #Celiac Disease and Mortality Risk in a Swedish Population
Cardiac #Autoimmunity Is Associated With Subclinical Myocardial Dysfunction in Patients With Type 1 #Diabetes Mellitus
The existence of a diabetic cardiomyopathy has been postulated to explain the increased risk of heart failure (HF) in patients with diabetes mellitus; however, whether mechanisms specific to type 1 diabetes mellitus (T1DM) affect the myocardium is unclear. We have recently shown that poor glycemic control in patients with T1DM followed in the DCCT (Diabetes… Continue reading Cardiac #Autoimmunity Is Associated With Subclinical Myocardial Dysfunction in Patients With Type 1 #Diabetes Mellitus
Early Transmission Dynamics in Wuhan, China, of Novel #Coronavirus–Infected Pneumonia
The initial cases of novel coronavirus (2019-nCoV)–infected pneumonia (NCIP) occurred in Wuhan, Hubei Province, China, in December 2019 and January 2020. We analyzed data on the first 425 confirmed cases in Wuhan to determine the epidemiologic characteristics of NCIP.. ..Among the first 425 patients with confirmed NCIP, the median age was 59 years and 56%… Continue reading Early Transmission Dynamics in Wuhan, China, of Novel #Coronavirus–Infected Pneumonia
Thinking ahead and staying in the present: Implications for reactivity to daily stressors
We examined how proactive coping and daily mindfulness may work together to predict emotional reactivity to daily stressors. Using data from the Mindfulness and Anticipatory Coping Everyday study (MACE; Neupert & Bellingtier, 2017; Neupert & Bellingtier, 2019), 116 older adults and 107 younger adults participated in a daily diary study for nine consecutive days. Results… Continue reading Thinking ahead and staying in the present: Implications for reactivity to daily stressors
Central sensory-motor crosstalk in the neural gut-brain axis
The neural gut-brain axis consists of viscerosensory and autonomic motor neurons innervating the gastrointestinal (GI) tract. Sensory neurons transmit nutrient-related and non-nutrient-related information to the brain, while motor neurons regulate GI motility and secretion. Previous research provides an incomplete picture of the brain nuclei that are directly connected with the neural gut-brain axis, and no… Continue reading Central sensory-motor crosstalk in the neural gut-brain axis
Respiratory virus shedding in exhaled breath and efficacy of face #masks
We identified seasonal human coronaviruses, influenza viruses and rhinoviruses in exhaled breath and coughs of children and adults with acute respiratory illness. Surgical face masks significantly reduced detection of influenza virus RNA in respiratory droplets and coronavirus RNA in aerosols, with a trend toward reduced detection of coronavirus RNA in respiratory droplets. Our results indicate… Continue reading Respiratory virus shedding in exhaled breath and efficacy of face #masks
Evolving Epidemiology and Impact of Non-pharmaceutical Interventions on the Outbreak of #Coronavirus Disease 2019 in Wuhan, China
..The median age of the cases was 57 years and 50.3% were women. The attack rate peaked in the third period and substantially declined afterwards across geographic regions, sex and age groups, except for children (age <20) whose attack rate continued to increase. Healthcare workers and elderly people had higher attack rates and severity risk… Continue reading Evolving Epidemiology and Impact of Non-pharmaceutical Interventions on the Outbreak of #Coronavirus Disease 2019 in Wuhan, China
A high-#salt diet compromises antibacterial neutrophil responses through hormonal perturbation
The Western diet is rich in salt, which poses various health risks. A high-salt diet (HSD) can stimulate immunity through the nuclear factor of activated T cells 5 (Nfat5)–signaling pathway, especially in the skin, where sodium is stored. The kidney medulla also accumulates sodium to build an osmotic gradient for water conservation. Here, we studied… Continue reading A high-#salt diet compromises antibacterial neutrophil responses through hormonal perturbation
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