BackgroundBoth the number of risky health behaviours and the duration of exposure to these behaviours over time may increase the risk of later adverse outcomes. This study examined cumulative associations of risky health behaviours with both positive and negative aspects of mental well-being and health. It has a uniquely long follow-up period of over 30 years,… Continue reading Cumulative associations between #health behaviours, mental well-being, and health over 30 years
Category: Sports
#Exercise without Weight Loss Prevents Seasonal Decline in Vitamin #D Metabolites: The VitaDEx Randomized Controlled Trial
Many adults become vitamin D deficient or insufficient during winter at northerly latitudes when cutaneous vitamin D synthesis does not occur. Vitamin D accumulates in adipose tissue and people with overweight or obesity are more likely to have low systemic vitamin D. This randomized controlled trial demonstrates that regular exercise completely maintains serum concentrations of… Continue reading #Exercise without Weight Loss Prevents Seasonal Decline in Vitamin #D Metabolites: The VitaDEx Randomized Controlled Trial
Dose Response of Incidental Physical #Activity Against #Cardiovascular Events and Mortality
Few middle-aged and older adults engage in regular leisure-time exercise. Incidental physical activity (IPA) encompasses activities of daily living outside the leisure-time domain. No dose-response study is available to guide IPA-focused interventions and guidelines. We examined the associations of device-assessed IPA intensities (vigorous [VIPA], moderate [MIPA], light [LIPA]) with major adverse cardiovascular events (MACE) and… Continue reading Dose Response of Incidental Physical #Activity Against #Cardiovascular Events and Mortality
Association of Accelerometer‐Derived #Physical Activity Pattern With the Risks of All‐Cause, #Cardiovascular Disease, and Cancer Death
Current guidelines suggest engaging in a minimum of 150 minutes of moderate to vigorous physical activity (MVPA) each week to support overall health. However, the effect of concentrated versus evenly distributed physical activity (PA) on health outcomes remains uncertain. This study aims to investigate the associations of “weekend warrior” pattern, where most MVPA is completed… Continue reading Association of Accelerometer‐Derived #Physical Activity Pattern With the Risks of All‐Cause, #Cardiovascular Disease, and Cancer Death
Reversible reduction in brain #myelin content upon #marathon running
Here we use magnetic resonance imaging to study the impact of marathon running on brain structure in humans. We show that the signal for myelin water fraction—a surrogate of myelin content—is substantially reduced upon marathon running in specific brain regions involved in motor coordination and sensory and emotional integration, but recovers within two months. These… Continue reading Reversible reduction in brain #myelin content upon #marathon running
Impact of different types of physical #exercise on sleep quality in older population with #insomnia: a systematic review and network meta-analysis of randomised controlled trials
Objective To measure the impact of each type of exercise on sleep quality and identify the exercise that enhances sleep quality the most.Study selection Eligible randomised controlled trials that compare physical exercise to routine activities, usual care, non-physical activity, or health education to measure the Pittsburgh Sleep Quality Index.Data source Studies retrieved from Medline, Embase,… Continue reading Impact of different types of physical #exercise on sleep quality in older population with #insomnia: a systematic review and network meta-analysis of randomised controlled trials
Individual and additive effects of vitamin #D, #omega-3 and #exercise on DNA methylation clocks of biological aging in older adults from the DO-HEALTH trial
While observational studies and small pilot trials suggest that vitamin D, omega-3 and exercise may slow biological aging, larger clinical trials testing these treatments individually or in combination are lacking. Here, we report the results of a post hoc analysis among 777 participants of the DO-HEALTH trial on the effect of vitamin D (2,000 IU per… Continue reading Individual and additive effects of vitamin #D, #omega-3 and #exercise on DNA methylation clocks of biological aging in older adults from the DO-HEALTH trial
Association between recorded #physical activity and cancer progression or mortality in individuals diagnosed with #cancer in South Africa
Objectives This study aimed to determine the association between progression and mortality in individuals with stage 1 cancer and their recorded physical activity before the diagnosis of the cancer.Methods We included 28 248 members with stage 1 cancers enrolled in an oncology programme in South Africa. Physical activity was recorded using fitness devices, logged gym sessions… Continue reading Association between recorded #physical activity and cancer progression or mortality in individuals diagnosed with #cancer in South Africa
Device-measured vigorous intermittent lifestyle #physical activity (VILPA) and major adverse cardiovascular events: evidence of sex differences
Background Vigorous intermittent lifestyle physical activity (VILPA) refers to brief bouts of intense physical activity embedded into daily life.Objective To examine sex differences in the dose–response association of VILPA with major adverse cardiovascular events (MACE) and its subtypes.Methods Using multivariable-adjusted cubic splines, we examined the associations of daily VILPA duration with overall MACE and its… Continue reading Device-measured vigorous intermittent lifestyle #physical activity (VILPA) and major adverse cardiovascular events: evidence of sex differences