Each year, the American Cancer Society estimates the numbers of new cancer cases and deaths in the United States and compiles the most recent data on population‐based cancer occurrence. Incidence data (through 2017) were collected by the Surveillance, Epidemiology, and End Results Program; the National Program of Cancer Registries; and the North American Association of… Continue reading #Cancer Statistics, 2021
Category: Oncology
Racial Disparities in Epigenetic Aging of the Right vs Left #Colon
There are well-documented racial differences in age-of-onset and laterality of colorectal cancer. Epigenetic age acceleration is postulated to be an underlying factor. However, comparative studies of side-specific colonic tissue epigenetic aging are lacking. Here, we performed DNA methylation analysis of matched right and left biopsies of normal colon from 128 individuals. Among African Americans (n = 88),… Continue reading Racial Disparities in Epigenetic Aging of the Right vs Left #Colon
Predicted #Heart Age Among #Cancer Survivors
What is already known about this topic? Cancer and cardiovascular disease (CVD) share long-term risk factors. Physician-patient communication using heart age has been effective in motivating patients to improve modifiable CVD risk factors. What is added by this report? The predicted heart age and excess heart age among cancer survivors were 57.2 and 8.5 years,… Continue reading Predicted #Heart Age Among #Cancer Survivors
Lower abdominal and pelvic radiation and #testicular germ cell tumor risk
Testicular germ cell tumor (TGCT) incidence has increased in recent decades along with the use and dose of diagnostic radiation. Here we examine the association between reported exposure to diagnostic radiation and TGCT risk.. ..There were 315 men with TGCT and 931 men without TGCT in our study. Compared to no exposures, risk of TGCT… Continue reading Lower abdominal and pelvic radiation and #testicular germ cell tumor risk
Association between Neu5Gc carbohydrate and serum antibodies against it provides the molecular link to #cancer: French NutriNet-Santé study
High consumption of red and processed meat is commonly associated with increased cancer risk, particularly colorectal cancer. Antibodies against the red meat-derived carbohydrate N-glycolylneuraminic acid (Neu5Gc) exacerbate cancer in “human-like” mice. Human anti-Neu5Gc IgG and red meat are both independently proposed to increase cancer risk, yet how diet affects these antibodies is largely unknown.. ..We… Continue reading Association between Neu5Gc carbohydrate and serum antibodies against it provides the molecular link to #cancer: French NutriNet-Santé study
Linked Color Imaging Focused on Neoplasm Detection in the Upper Gastrointestinal Tract
Linked color imaging (LCI) is a new image-enhanced endoscopy technique that allows users to recognize slight differences in mucosal color To compare the performance of LCI with white light imaging (WLI) in detecting neoplastic lesions in the upper gastrointestinal tract.. ..752 patients were assigned to the WLI group and 750 to the LCI group. The… Continue reading Linked Color Imaging Focused on Neoplasm Detection in the Upper Gastrointestinal Tract
Effect of time of day of recreational and household #physical activity on prostate and breast #cancer risk (MCC‐Spain study)
Experimental evidence indicates that exercise performed at different times of the day may affect circadian rhythms and circadian disruption has been linked to breast and prostate cancer. We examined in a population‐based case‐control study (MCC‐Spain) if the time‐of‐day when physical activity is done affects prostate and breast cancer risk. Lifetime recreational and household physical activity… Continue reading Effect of time of day of recreational and household #physical activity on prostate and breast #cancer risk (MCC‐Spain study)
Association of postoperative #influenza vaccine on overall mortality in patients undergoing curative surgery for solid #tumors
Recent findings have found that the influenza vaccine induces changes in the immune system in favor of anti‐tumor cytotoxicity. The aim in this study was to investigate if an influenza vaccine given in the postoperative period decreased overall and cancer‐specific mortality in patients undergoing curative surgery for solid cancers. We conducted a registry‐based national observational… Continue reading Association of postoperative #influenza vaccine on overall mortality in patients undergoing curative surgery for solid #tumors
Association Between #Atopic Eczema and #Cancer in England and Denmark
Associations between atopic eczema and cancer are unclear, with competing theories that increased immune surveillance decreases cancer risk and that immune stimulation increases cancer risk. Establishing baseline cancer risk in people with atopic eczema is important before exploring the association between new biologic drugs for atopic eczema and cancer risk.. ..In England, matched cohorts included… Continue reading Association Between #Atopic Eczema and #Cancer in England and Denmark
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