The concept of embolic stroke of undetermined source (ESUS) unifies a subgroup of cryptogenic strokes based on neuroimaging, a defined minimum set of diagnostic tests, and exclusion of certain causes. Despite an annual stroke recurrence rate of 5%, little is known about the etiology underlying recurrent stroke after ESUS.. ..A total of 309 patients (205… Continue reading Characteristics of Recurrent Ischemic #Stroke After Embolic Stroke of Undetermined Source Secondary Analysis of a Randomized Clinical Trial
Category: Neurology
Association Between #Epidural Analgesia During Labor and Risk of #Autism Spectrum Disorders in Offspring
Although the safety of labor epidural analgesia (LEA) for neonates has been well documented, the long-term health effects of LEA on offspring remain to be investigated... ..Among the cohort of 147 895 singleton children (74 425 boys [50.3%]; mean [SD] gestational age at delivery, 38.9 [1.5] weeks), 109 719 (74.2%) were exposed to maternal LEA. Fever during labor… Continue reading Association Between #Epidural Analgesia During Labor and Risk of #Autism Spectrum Disorders in Offspring
Neurofilament light chain in the vitreous humor of the #eye
Neurofilament light chain (NfL) is a promising biomarker of neurodegeneration in the cerebrospinal fluid and blood. This study investigated the presence of NfL in the vitreous humor and its associations with amyloid beta, tau, inflammatory cytokines and vascular proteins, apolipoprotein E (APOE) genotypes, Mini-Mental State Examination (MMSE) scores, systemic disease, and ophthalmic diseases.. ..NfL was… Continue reading Neurofilament light chain in the vitreous humor of the #eye
The Importance of Cursive #Handwriting Over Typewriting for Learning in the Classroom: A High-Density #EEG Study of 12-Year-Old Children and Young Adults
To write by hand, to type, or to draw – which of these strategies is the most efficient for optimal learning in the classroom? As digital devices are increasingly replacing traditional writing by hand, it is crucial to examine the long-term implications of this practice. High-density electroencephalogram (HD EEG) was used in 12 young adults… Continue reading The Importance of Cursive #Handwriting Over Typewriting for Learning in the Classroom: A High-Density #EEG Study of 12-Year-Old Children and Young Adults
Evaluation of #green light exposure on #headache frequency and quality of life in #migraine patients: A preliminary one-way cross-over clinical trial
..We recruited (29 total) patients, of whom seven had episodic migraine and 22 had chronic migraine. We used a one-way cross-over design consisting of exposure for 1–2 hours daily to white light emitting diodes for 10 weeks, followed by a 2-week washout period followed by exposure for 1–2 hours daily to green light emitting diodes… Continue reading Evaluation of #green light exposure on #headache frequency and quality of life in #migraine patients: A preliminary one-way cross-over clinical trial
Relationship Among Sensory Over-Responsivity, Problem Behaviors, and #Anxiety in Emerging Adults with #Autism Spectrum Disorder
Despite the highly prevailing rate of sensory over-responsivity, problem behaviors, and anxiety among emerging adults with autism spectrum disorder (ASD), little is known about the nature of their experiences. While previous studies have indicated potential relationships among these conditions, their connections still need to be clarified. This study aimed to examine the relationships between sensory… Continue reading Relationship Among Sensory Over-Responsivity, Problem Behaviors, and #Anxiety in Emerging Adults with #Autism Spectrum Disorder
#Language comprehension in the social #brain: Electrophysiological brain signals of social presence effects during syntactic and semantic sentence processing
Although, evolutionarily, language emerged predominantly for social purposes, much has yet to be uncovered regarding how language processing is affected by social context. Social presence research studies the ways in which the presence of a conspecific affects processing, but has yet to be thoroughly applied to language processes. The principal aim of this study was… Continue reading #Language comprehension in the social #brain: Electrophysiological brain signals of social presence effects during syntactic and semantic sentence processing
#Anticoagulation Timing in Cardioembolic #Stroke and Recurrent Event Risk
Guidelines recommend initiating anticoagulation within 4 to 14 days after cardioembolic stroke. Data supporting this did not account for key factors potentially affecting the decision to initiate anticoagulation, such as infarct size, hemorrhagic transformation, or high‐risk features on echocardiography.. ..We pooled data from stroke registries of 8 comprehensive stroke centers across the United States. We included… Continue reading #Anticoagulation Timing in Cardioembolic #Stroke and Recurrent Event Risk
Transcriptomic and clonal characterization of #T cells in the human central #nervous system
T cells provide critical immune surveillance to the central nervous system (CNS), and the cerebrospinal fluid (CSF) is thought to be a main route for their entry. Further characterization of the state of T cells in the CSF in healthy individuals is important for understanding how T cells provide protective immune surveillance without damaging the… Continue reading Transcriptomic and clonal characterization of #T cells in the human central #nervous system