Background and ObjectivesThe Systolic Blood Pressure Intervention Trial suggested that intensive lowering of systolic blood pressure (SBP) decreases the risk of developing dementia. However, an insufficient number of probable dementia cases stemming from the trial's early termination made results inconclusive. The goal of this study was to estimate the effect of intensive vs standard SBP… Continue reading Long-Term Effect of Intensive vs Standard Blood #Pressure Control on Mild Cognitive Impairment and Probable #Dementia in SPRINT
Category: Hypertension
Short #Sleep Duration and #Hypertension: A Double Hit for the #Brain
Short sleep duration has been associated with an increased risk of cognitive impairment and dementia. Short sleep is associated with elevated blood pressure, yet the combined insult of short sleep and hypertension on brain health remains unclear. We assessed whether the association of sleep duration with cognition and vascular brain injury was moderated by hypertensive… Continue reading Short #Sleep Duration and #Hypertension: A Double Hit for the #Brain
Blood #Pressure Variability and #Cognition in Black and White Older Adults Over 18 Years of Follow-up
Background and ObjectivesHypertension is a well-established cardiovascular risk factor for cognitive function. As blood pressure fluctuates because of aging-related changes, we examined the association between visit-to-visit blood pressure variability (BPV) and cognition in older adults. MethodsThis prospective observational cohort study included 4,770 individuals aged older than 65 years with repeated blood pressure assessment participating in… Continue reading Blood #Pressure Variability and #Cognition in Black and White Older Adults Over 18 Years of Follow-up
Blood #Pressure Decreases in #Overweight Elderly Individuals on Vitamin #D: A Randomized Trial
AbstractContextEvidence for a beneficial role of vitamin D on blood pressure (BP) outcomes is inconclusive.ObjectiveThis work aimed to investigate the effect of 2 doses of cholecalciferol (vitamin D3) supplementation coadministered with calcium on systolic blood pressure (SBP) and diastolic blood pressure (DBP).MethodsExploratory analyses were conducted from a 1-year, multicenter, double-blind, randomized controlled trial (RCT). Total… Continue reading Blood #Pressure Decreases in #Overweight Elderly Individuals on Vitamin #D: A Randomized Trial
#Arm Position and Blood #Pressure ReadingsThe ARMS Crossover Randomized Clinical Trial
Key PointsQuestion What is the effect of commonly used arm positions on blood pressure (BP) measurements compared to the standard, recommended position?Findings This crossover randomized clinical trial of 133 adults showed that supporting the arm on the lap overestimated systolic BP by 3.9 mm Hg and diastolic BP by 4.0 mm Hg. An unsupported arm… Continue reading #Arm Position and Blood #Pressure ReadingsThe ARMS Crossover Randomized Clinical Trial
Low-Dose Triple-Pill vs Standard-Care Protocols for #Hypertension Treatment in NigeriaA Randomized Clinical Trial
Importance With the high burden of hypertension in sub-Saharan Africa, there is a need for effective, safe and scalable treatment strategies.Objective To compare, among Black African adults, the effectiveness and safety of a novel low-dose triple-pill protocol compared with a standard-care protocol for blood pressure lowering.Design and Setting Randomized, parallel-group, open-label, multicenter trial conducted in public hospital–based family medicine… Continue reading Low-Dose Triple-Pill vs Standard-Care Protocols for #Hypertension Treatment in NigeriaA Randomized Clinical Trial
Effects of #Cocoa Consumption on #Cardiometabolic Risk Markers: Meta-Analysis of Randomized Controlled Trials
Abstract: Background: We conducted a systematic review and meta-analysis to examine the effect of dietary intake of cocoa on anthropometric measurements, lipid and glycemic profiles, and blood pressure levels in adults, with and without comorbidities. Methods: The databases used were MEDLINE (PubMed), EMBASE, Web of Science, Cochrane, LILACS, and SciELO. The eligible studies were randomized… Continue reading Effects of #Cocoa Consumption on #Cardiometabolic Risk Markers: Meta-Analysis of Randomized Controlled Trials
Effect of timed dosing of usual #antihypertensives according to patient chronotype on #cardiovascular outcomes: the Chronotype sub-study cohort of the Treatment in Morning versus Evening (TIME) study
BackgroundTiming drug administration to endogenous circadian rhythms may enhance treatment efficacy. In the Chronotype sub-study of the Treatment in Morning versus Evening (TIME) clinical trial we examined whether timing of usual antihypertensive medications according to patient chronotype (a behavioural marker of personal circadian rhythm) may influence clinical cardiovascular outcomes.MethodsThis was a cohort sub-study of TIME,… Continue reading Effect of timed dosing of usual #antihypertensives according to patient chronotype on #cardiovascular outcomes: the Chronotype sub-study cohort of the Treatment in Morning versus Evening (TIME) study
Effect of #Tai Chi vs Aerobic #Exercise on Blood #Pressure in Patients With PrehypertensionA Randomized Clinical Trial
Importance Prehypertension increases the risk of developing hypertension and other cardiovascular diseases. Early and effective intervention for patients with prehypertension is highly important.Objective To assess the efficacy of Tai Chi vs aerobic exercise in patients with prehypertension.Design, Setting, and Participants This prospective, single-blinded randomized clinical trial was conducted between July 25, 2019, and January 24, 2022, at 2… Continue reading Effect of #Tai Chi vs Aerobic #Exercise on Blood #Pressure in Patients With PrehypertensionA Randomized Clinical Trial
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