Immunotoxicity and intestinal effects of nano- and microplastics: a review of the literature

BackgroundTogether with poor biodegradability and insufficient recycling, the massive production and use of plastics have led to widespread environmental contamination by nano- and microplastics. These particles accumulate across ecosystems - even in the most remote habitats - and are transferred through food chains, leading to inevitable human ingestion, that adds to the highest one due… Continue reading Immunotoxicity and intestinal effects of nano- and microplastics: a review of the literature

Non-target screening for the identification of migrating compounds from reusable plastic bottles into drinking water

Highlights•Migration of > 400 plastic related and > 3500 dishwasher related compounds. •The dishwashing process increased the migration of plastic related compounds. •Oligomers suspected from polycaprolactone (PCL) were migrating. •Three of the identified photoinitiators have possible endocrine disrupting effects. •Diethyltoluamide (DEET) may have been formed from the plasticizer laurolactam. AbstractReusable plastic sports bottles are used… Continue reading Non-target screening for the identification of migrating compounds from reusable plastic bottles into drinking water

School closure and management practices during coronavirus outbreaks including COVID-19: a rapid systematic review

In response to the coronavirus disease 2019 (COVID-19) pandemic, 107 countries had implemented national school closures by March 18, 2020. It is unknown whether school measures are effective in coronavirus outbreaks (eg, due to severe acute respiratory syndrome [SARS], Middle East respiratory syndrome, or COVID-19). We undertook a systematic review by searching three electronic databases… Continue reading School closure and management practices during coronavirus outbreaks including COVID-19: a rapid systematic review

Adolescent psychiatric disorders during the COVID-19 pandemic and lockdown

Highlights•The COVID-19 pandemic and lockdown may have a negative impact on the mental health of adolescents. •Epidemics and disasters are associated with adolescent Post Traumatic Stress, Depression, and Anxiety symptoms. •Healthcare system adaptations are necessary for mental health support despite the lockdown. •Home confinement may be associated with increased intrafamilial violence. •Data is scarce on… Continue reading Adolescent psychiatric disorders during the COVID-19 pandemic and lockdown

Air quality improvement and cognitive decline in community-dwelling older women in the United States: A longitudinal cohort study

Late-life exposure to ambient air pollution is a modifiable risk factor for dementia, but epidemiological studies have shown inconsistent evidence for cognitive decline. Air quality (AQ) improvement has been associated with improved cardiopulmonary health and decreased mortality, but to the best of our knowledge, no studies have examined the association with cognitive function. We examined… Continue reading Air quality improvement and cognitive decline in community-dwelling older women in the United States: A longitudinal cohort study

Adipogenic Activity of Chemicals Used in Plastic Consumer Products

Bisphenols and phthalates, chemicals frequently used in plastic products, promote obesity in cell and animal models. However, these well-known metabolism-disrupting chemicals (MDCs) represent only a minute fraction of all compounds found in plastics. To gain a comprehensive understanding of plastics as a source of exposure to MDCs, we characterized the chemicals present in 34 everyday… Continue reading Adipogenic Activity of Chemicals Used in Plastic Consumer Products

A LITERATURE REVIEW AND META-ANALYSISOF THE EFFECTS OF LOCKDOWNS ONCOVID-19 MORTALITY

This systematic review and meta-analysis are designed to determine whether there is empiricalevidence to support the belief that “lockdowns” reduce COVID-19 mortality. Lockdowns aredefined as the imposition of at least one compulsory, non-pharmaceutical intervention (NPI).NPIs are any government mandate that directly restrict peoples’ possibilities, such as policies thatlimit internal movement, close schools and businesses, and… Continue reading A LITERATURE REVIEW AND META-ANALYSISOF THE EFFECTS OF LOCKDOWNS ONCOVID-19 MORTALITY

Rapid emergence of SARS-CoV-2 Omicron variant is associated with an infection advantage over Delta in vaccinated persons

The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants continues to shape the coronavirus disease 2019 (Covid-19) pandemic. The detection and rapid spread of the SARS-CoV-2 Omicron variant (lineage B.1.1.529) in Botswana and South Africa became a global concern because it contained 15 mutations in the spike protein immunogenic receptor binding domain and… Continue reading Rapid emergence of SARS-CoV-2 Omicron variant is associated with an infection advantage over Delta in vaccinated persons

The Lancet: COVID-19 pandemic led to stark rise in depressive and anxiety disorders globally in 2020, with women and younger people most affected

First global estimates of impact of the COVID-19 pandemic on mental health in 2020 suggests additional 53 million cases of major depressive disorder and 76 million cases of anxiety disorders were due to the pandemic.Women and younger people were the most affected by major depressive disorder and anxiety disorders in 2020.Countries hit hardest by the… Continue reading The Lancet: COVID-19 pandemic led to stark rise in depressive and anxiety disorders globally in 2020, with women and younger people most affected