Background & AimsTetrachloroethylene (PCE) is a volatile organic compound (VOC) used in industrial settings. Pre-clinical studies have linked PCE to hepatotoxicity, but clinical data beyond selected occupational cohorts represent a critical knowledge gap.MethodsWe utilised data from the National Health and Nutrition Examination Survey (NHANES) from 2017 to 2020, a nationally representative survey of the US… Continue reading #Tetrachloroethylene Is Associated With Presence of Significant Liver #Fibrosis: A National Cross-Sectional Study in US Adults
Category: Environment
Short-term association between ambient air #pollution and #heart #rate variability: results from the population-based KORA S4 and FF4 studies
Background: Ambient air pollution is a major risk factor for CVDs, and a plausible mechanism is speculated to be alteration of autonomic nervous system (ANS) function. Yet, the short-term effects of air pollution on heart rate variability (HRV), a measure of ANS balance are inconsistent.Objective: This study aimed to evaluate the short-term effects of ambient… Continue reading Short-term association between ambient air #pollution and #heart #rate variability: results from the population-based KORA S4 and FF4 studies
#432 Hz Frequency Benefits: A Comprehensive Guide
#Music has always held the power to move, heal, and inspire. But beyond melody and rhythm, the frequencies at which music is tuned can also influence how it affects us. One frequency, in particular, has captured the imagination of musicians, healers, and sound therapists around the world: 432 Hz. Often referred to as the "natural… Continue reading #432 Hz Frequency Benefits: A Comprehensive Guide
#Thermal and Perceptual Responses of #Older Adults With #Fan Use in #Heat ExtremesA Secondary Analysis of a Randomized Clinical Trial
The US Centers for Disease Control and Prevention (CDC) advise against fan use above 32 °C (ie, 90 °F) because it can increase body temperature.1 Modeling suggests fans reduce body temperature up to 37 to 39 °C (ie, 99 to 102 °F), depending upon humidity.2 In humid heat, fan use reduced body temperature in young… Continue reading #Thermal and Perceptual Responses of #Older Adults With #Fan Use in #Heat ExtremesA Secondary Analysis of a Randomized Clinical Trial
Exposure to per- and poly-fluoroalkyl substances in association to later occurrence of type 2 #diabetes and metabolic pathway #dysregulation in a multiethnic US population
Growing evidence suggests that exposure to per- and polyfluoroalkyl substances ( #PFAS ) are linked to an increased risk of type 2 diabetes (T2D); however, the effect of PFAS mixtures and underlying mechanisms are not well understood. We examined the associations between exposure to PFAS mixture with later T2D diagnosis and underlying metabolic dysregulations.MethodsWe conducted… Continue reading Exposure to per- and poly-fluoroalkyl substances in association to later occurrence of type 2 #diabetes and metabolic pathway #dysregulation in a multiethnic US population
Effects of various #exercise interventions in #insomnia patients: a systematic review and network meta-analysis
Objectives To compare the effectiveness of different exercise interventions in improving sleep quality and alleviating insomnia severity among patients with insomnia.Design Our study design was a systematic review and network meta-analysis.Eligibility criteria Our study eligibility criteria was restricted to include randomised controlled trials (RCTs) involving adults with insomnia that evaluated exercise-based interventions.Data sources PubMed, Cochrane… Continue reading Effects of various #exercise interventions in #insomnia patients: a systematic review and network meta-analysis
Personal night #light exposure predicts incidence of #cardiovascular diseases in >88,000 individuals
Importance Light at night causes circadian disruption, which is a known risk factor for adverse cardiovascular outcomes. However, it is not well understood whether personal light exposure patterns predicts and individual’s risk of cardiovascular diseases.Objective To assess whether day and night light exposure predicts incidence of cardiovascular diseases, and whether relationships of light with cardiovascular… Continue reading Personal night #light exposure predicts incidence of #cardiovascular diseases in >88,000 individuals
Early prenatal #nitrate exposure and #birth outcomes: A study of Iowa’s public drinking water (1970–1988)
Despite the biological mechanisms linking prenatal nitrate exposure to birth outcomes, epidemiological research has been inconclusive. The evidence-base has been limited by where and how nitrate exposure was measured, and the spurious correlation between geotemporal nitrate heterogeneity and unmeasurable factors contributing to gestational age and birth weight. We linked Iowa water quality data and birth… Continue reading Early prenatal #nitrate exposure and #birth outcomes: A study of Iowa’s public drinking water (1970–1988)
0350 Objectively-Assessed #Napping Behaviors Predict #Mortality in Middle-to-Older Aged #Adults
IntroductionSelf-reported daytime napping is associated with various adverse health outcomes. We examined whether actigraphy-measured objective daytime napping behaviors predict all-cause mortality in middle-to-older aged adults in the UK Biobank.MethodsWe studied 86,565 participants (baseline age=63 years, SD=8, range: 43-79; 57% female) in the UK Biobank who did not have shiftwork history, completed a 7-day actigraphy monitoring,… Continue reading 0350 Objectively-Assessed #Napping Behaviors Predict #Mortality in Middle-to-Older Aged #Adults
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