Dietary #Carbohydrate Intake, Carbohydrate Quality, and Healthy #Aging in Women

Importance  Dietary carbohydrate quality is inversely associated with risks of chronic disease and all-cause mortality. However, limited evidence exists regarding the role of carbohydrate quality and dietary carbohydrate types in promoting healthy aging.Objective  To evaluate the long-term role of dietary carbohydrate intake and carbohydrate quality in healthy aging.Design, Setting, and Participants  This prospective cohort study… Continue reading Dietary #Carbohydrate Intake, Carbohydrate Quality, and Healthy #Aging in Women

3-month program of time-restricted #eating at any time of the day supports long-term #weight loss in adults with overweight or obesity

Three months of time-restricted eating (TRE), irrespective of whether it is earlier or later in the day, may be a promising strategy for sustaining long-term weight loss in adults with overweight or obesity, according to preliminary results of a randomised controlled trial being presented at this year’s European Congress on Obesity (ECO) in Malaga, Spain… Continue reading 3-month program of time-restricted #eating at any time of the day supports long-term #weight loss in adults with overweight or obesity

60 is the new 40: preparing for better bone #health in later life

Objective: In this study we evaluated associations between nutritional factors, including calcium supplementation, and outcomes of fracture and cardiovascular mortality. We chose to report both outcomes as an illustration of the importance of nutritional factors in midlife to heart disease as this may be more impactful for supporting behavior change strategies, particularly in men.Methods: This… Continue reading 60 is the new 40: preparing for better bone #health in later life

Association Between #Alcohol Consumption, #Cognitive Abilities, and Neuropathologic Changes

Background and ObjectivesHeavy alcohol consumption is a major global health concern linked to increased morbidity and mortality. However, the long-term impact of excessive alcohol consumption on cognitive abilities and dementia-related neuropathology is unclear. The aim of this study was to analyze the association between alcohol consumption and age-related neuropathologic outcomes in a population-based autopsy study.MethodsThis… Continue reading Association Between #Alcohol Consumption, #Cognitive Abilities, and Neuropathologic Changes

Immune and metabolic effects of African heritage #diets versus Western diets in men: a randomized controlled trial

African heritage diets are increasingly being replaced by Western-style dietary patterns because of urbanization, economic development, increased access to processed foods, globalization and changing social norms. The health consequences of this nutrition transition are not well understood. We conducted a randomized controlled trial in the Kilimanjaro region in Northern Tanzania to investigate the immune and… Continue reading Immune and metabolic effects of African heritage #diets versus Western diets in men: a randomized controlled trial

Non-caloric #sweetener effects on brain appetite regulation in individuals across varying body #weights

Sucralose, a widely used non-caloric sweetener, provides sweet taste without calories. Some studies suggest that non-caloric sweeteners stimulate appetite, possibly owing to the delivery of a sweet taste without the post-ingestive metabolic signals that normally communicate with the hypothalamus to suppress hunger. In a randomized crossover trial (ClinicalTrials.gov identifier: NCT02945475), 75 young adults (healthy weight,… Continue reading Non-caloric #sweetener effects on brain appetite regulation in individuals across varying body #weights

High- #salt #diet drives depression-like behavior in mice by inducing IL-17A production

Major depression disorder is a common illness that severely limits psychosocial functioning, affects outcomes of other diseases, and diminishes the quality of life. High-salt diet (HSD) has long been closely associated with the occurrence and development of depression, but whether or how HSD causes depression remains unclear. In this study, HSD induces depression-like behavior in… Continue reading High- #salt #diet drives depression-like behavior in mice by inducing IL-17A production

The Effect of 4:3 Intermittent #Fasting on #Weight Loss at 12 Months: A Randomized Clinical Trial

AbstractBackground:Long-term (≥12 months) randomized trials evaluating the efficacy of intermittent fasting (IMF) as a dietary weight loss strategy are limited. Furthermore, no studies have compared IMF versus daily caloric restriction (DCR) when both interventions are provided in the context of a guidelines-based behavioral weight loss program.Objective:To compare the effects of 4:3 IMF versus DCR on… Continue reading The Effect of 4:3 Intermittent #Fasting on #Weight Loss at 12 Months: A Randomized Clinical Trial

Optimal #dietary patterns for healthy #aging

As the global population ages, it is critical to identify diets that, beyond preventing noncommunicable diseases, optimally promote healthy aging. Here, using longitudinal questionnaire data from the Nurses’ Health Study (1986–2016) and the Health Professionals Follow-Up Study (1986–2016), we examined the association of long-term adherence to eight dietary patterns and ultraprocessed food consumption with healthy… Continue reading Optimal #dietary patterns for healthy #aging