AbstractBACKGROUND:Behavioral weight management programs (BWMPs) enhance weight loss in the short term, but longer term cardiometabolic effects are uncertain as weight is commonly regained. We assessed the impact of weight regain after BWMPs on cardiovascular risk factors, diabetes, and cardiovascular disease.METHODS:Trial registries, 11 databases, and forward-citation searching (latest search, December 19) were used to identify… Continue reading Long-Term Effect of Weight Regain Following Behavioral Weight Management Programs on Cardiometabolic Disease Incidence and Risk: Systematic Review and Meta-Analysis
Category: Diet
C-reactive protein partially mediates the inverse association between coffee consumption and risk of type 2 diabetes: The UK Biobank and the Rotterdam study cohorts
BackgroundCoffee is among the most consumed beverages worldwide. Coffee consumption has been associated with lower risk of type 2 diabetes mellitus (T2D), but underlying mechanisms are not well understood. We aimed to study the role of classic and novel-T2D biomarkers with anti- or pro-inflammatory activity in the association between habitual coffee intake and T2D risk.… Continue reading C-reactive protein partially mediates the inverse association between coffee consumption and risk of type 2 diabetes: The UK Biobank and the Rotterdam study cohorts
Subclinical Coronary Atherosclerosis and Risk for Myocardial Infarction in a Danish CohortA Prospective Observational Cohort Study
Background:Coronary atherosclerosis may develop at an early age and remain latent for many years.Objective:To define characteristics of subclinical coronary atherosclerosis associated with the development of myocardial infarction.Design:Prospective observational cohort study.Setting:Copenhagen General Population Study, Denmark.Participants:9533 asymptomatic persons aged 40 years or older without known ischemic heart disease.Measurements:Subclinical coronary atherosclerosis was assessed with coronary computed tomography angiography… Continue reading Subclinical Coronary Atherosclerosis and Risk for Myocardial Infarction in a Danish CohortA Prospective Observational Cohort Study
Anthocyanins as Promising Molecules Affecting Energy Homeostasis, Inflammation, and Gut Microbiota in Type 2 Diabetes with Special Reference to Impact of Acylation
Anthocyanins, the red-orange to blue-violet colorants present in fruits, vegetables, and tubers, have antidiabetic properties expressed via modulating energy metabolism, inflammation, and gut microbiota. Acylation of the glycosyl moieties of anthocyanins alters the physicochemical properties of anthocyanins and improves their stability. Thus, acylated anthocyanins with probiotic-like property and lower bioavailability are likely to have different… Continue reading Anthocyanins as Promising Molecules Affecting Energy Homeostasis, Inflammation, and Gut Microbiota in Type 2 Diabetes with Special Reference to Impact of Acylation
Salt Sensitivity of Blood Pressure in Women
Several clinical and large population studies indicate that women are more salt-sensitive than men, yet the precise mechanisms by which the sexually dimorphic onset manifests remains incompletely understood. Here, we evaluate recent epidemiological data and highlight current knowledge from studies investigating sex-specific mechanisms of salt-sensitive blood pressure (SSBP). Emerging evidence indicates that women of all… Continue reading Salt Sensitivity of Blood Pressure in Women
Straight from the heart
Lipids called ceramides may be better predictors of cardiovascular problems than cholesterol. Doctors and pharma are waking up to their potential https://www.science.org/content/article/straight-heart-mysterious-lipids-may-predict-cardiac-problems-better-cholesterol
Primary prevention of cardiovascular disease in women with a Mediterranean diet: systematic review and meta-analysis
Background Dietary modification is a cornerstone of cardiovascular disease (CVD) prevention. A Mediterranean diet has been associated with a lower risk of CVD but no systematic reviews have evaluated this relationship specifically in women.Objective To determine the association between higher versus lower adherence to a Mediterranean diet and incident CVD and total mortality in women.Methods… Continue reading Primary prevention of cardiovascular disease in women with a Mediterranean diet: systematic review and meta-analysis
The artificial sweetener erythritol and cardiovascular event risk
Artificial sweeteners are widely used sugar substitutes, but little is known about their long-term effects on cardiometabolic disease risks. Here we examined the commonly used sugar substitute erythritol and atherothrombotic disease risk. In initial untargeted metabolomics studies in patients undergoing cardiac risk assessment (n = 1,157; discovery cohort, NCT00590200), circulating levels of multiple polyol sweeteners, especially erythritol,… Continue reading The artificial sweetener erythritol and cardiovascular event risk
Dietary magnesium intake is related to larger brain volumes and lower white matter lesions with notable sex differences
PurposeTo examine the association between dietary magnesium (Mg) intake and brain volumes and white matter lesions (WMLs) in middle to early old age.MethodsParticipants (aged 40–73 years) from UK Biobank (n = 6001) were included and stratified by sex. Dietary Mg was measured using an online computerised 24 h recall questionnaire to estimate daily Mg intake. Latent class… Continue reading Dietary magnesium intake is related to larger brain volumes and lower white matter lesions with notable sex differences
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