Gluten, which is found in cereals such as wheat, rye and barley, makes up a major dietary component in most western nations, and has been shown to promote body mass gain and peripheral inflammation in mice. In the current study, we investigated the impact of gluten on central inflammation that is typically associated with diet-induced… Continue reading Dietary wheat #gluten induces astro- and #microgliosis in the hypothalamus of male mice
Category: Diet
The #fructose survival hypothesis for #obesity
The fructose survival hypothesis proposes that obesity and metabolic disorders may have developed from over-stimulation of an evolutionary-based biologic response (survival switch) that aims to protect animals in advance of crisis. The response is characterized by hunger, thirst, foraging, weight gain, fat accumulation, insulin resistance, systemic inflammation and increased blood pressure. The process is initiated by the… Continue reading The #fructose survival hypothesis for #obesity
Association between added #sugars and kidney #stones in U.S. adults: data from National Health and Nutrition Examination Survey 2007–2018
Added sugar is associated with a variety of adverse health outcomes, but its association with kidney stones is unclear. This study was to determine whether added sugar is associated with kidney stones.Materials and methods: This nationally representative study used National Health and Nutrition Examination Survey (NHANES) datasets from 2007 to 2018 for analysis. People aged ≥20 years… Continue reading Association between added #sugars and kidney #stones in U.S. adults: data from National Health and Nutrition Examination Survey 2007–2018
Human #cells experience a #Zn2+ pulse in early G1
Highlights•Human cells experience a transient zinc pulse in early G1•The magnitude of the pulse tracks with the amount of zinc in the cytosol and media•Knockdown of MTF-1 decreases metallothionein and increases the zinc pulse•Cells pause proliferation until labile cellular zinc is in the optimum range SummaryZinc is an essential micronutrient required for all domains of… Continue reading Human #cells experience a #Zn2+ pulse in early G1
#Kombucha tea as an anti-hyperglycemic agent in humans with #diabetes – a randomized controlled pilot investigation
Introduction: Kombucha is a popular fermented tea that has attracted considerable attention due, in part, to its suggested health benefits. Previous results from animal models led us to hypothesize kombucha may reduce blood sugar levels in humans with diabetes. The objective of this pilot clinical study was to evaluate kombucha for its anti-hyperglycemic activities in adults… Continue reading #Kombucha tea as an anti-hyperglycemic agent in humans with #diabetes – a randomized controlled pilot investigation
#Ultra-processed #food consumption is associated with all-cause and #cardiovascular mortality in participants with type 2 #diabetes independent of diet quality: a prospective observational cohort study
BackgroundNutritional strategies for prevention and management of type 2 diabetes traditionally emphasize dietary patterns reflecting nutrient goals, but the health implications of ultra-processed food (UPF) for patients with type 2 diabetes remain unknown.ObjectiveTo evaluate the association of UPF intake with all-cause and cardiovascular disease (CVD) mortality amongst participants with type 2 diabetes from the Moli-sani… Continue reading #Ultra-processed #food consumption is associated with all-cause and #cardiovascular mortality in participants with type 2 #diabetes independent of diet quality: a prospective observational cohort study
#Espresso Coffee Mitigates the Aggregation and Condensation of #Alzheimer′s Associated Tau Protein
Espresso coffee is among the most consumed beverages in the world. Recent studies report a protective activity of the coffee beverage against neurodegenerative disorders such as Alzheimer′s disease. Alzheimer′s disease belongs to a group of disorders, called tauopathies, which are characterized by the intraneuronal accumulation of the microtubule-associated protein tau in fibrillar aggregates. In this… Continue reading #Espresso Coffee Mitigates the Aggregation and Condensation of #Alzheimer′s Associated Tau Protein
Vegetarian Dietary Patterns and Cardiometabolic Risk in People With or at High Risk of Cardiovascular DiseaseA Systematic Review and Meta-analysis
MPORTANCE Plant-based diets are known to improve cardiometabolic risk in the general population, but their effects on people at high risk of cardiovascular diseases (CVDs) remain inconclusive.OBJECTIVE To assess the association of vegetarian diets with major cardiometabolic risk factors,including low-density lipoprotein cholesterol (LDL-C), hemoglobin A1c (HbA1c), systolic blood pressure (SBP), and body weight in people… Continue reading Vegetarian Dietary Patterns and Cardiometabolic Risk in People With or at High Risk of Cardiovascular DiseaseA Systematic Review and Meta-analysis
Opting for olive oil could boost brain healthRegular olive oil consumption associated with 28% lower risk of fatal dementia
oil as part of a Mediterranean dietary pattern has also been shown to help protect against cognitive decline. Tessier cautioned that the research is observational and does not prove that olive oil is the cause of the reduced risk of fatal dementia. Additional studies such as randomized controlled trials would be needed to confirm the effects… Continue reading Opting for olive oil could boost brain healthRegular olive oil consumption associated with 28% lower risk of fatal dementia
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