Ultra-processed #foods and #cardiometabolic health: public health policies to reduce consumption cannot wait

Incomplete understanding of the multiple mechanisms underlying the link between ultra-processed foods and cardiometabolic health should not be an excuse for inaction argue Mathilde Touvier and colleaguesThe effect of diet on health has historically been considered from a nutrient based perspective—for example, excess total fat, saturated fat, dietary cholesterol, calories, sugar, or salt and lack of… Continue reading Ultra-processed #foods and #cardiometabolic health: public health policies to reduce consumption cannot wait

Use of #sugar in #coffee and #tea and long-term risk of #mortality in older adult Danish men: 32 years of follow-up from a prospective cohort study

Tea and coffee are the most consumed beverages worldwide and very often sweetened with sugar. However, the association between the use of sugar in tea or coffee and adverse events is currently unclear.ObjectivesTo investigate the association between the addition of sugar to coffee or tea, and the risk of all-cause mortality, cardiovascular mortality, cancer mortality… Continue reading Use of #sugar in #coffee and #tea and long-term risk of #mortality in older adult Danish men: 32 years of follow-up from a prospective cohort study

#Prebiotic #diet changes neural correlates of #food decision-making in #overweight adults: a randomised controlled within-subject cross-over trial 

Objective Animal studies suggest that prebiotic, plant-derived nutrients could improve homoeostatic and hedonic brain functions through improvements in microbiome–gut–brain communication. However, little is known if these results are applicable to humans. Therefore, we tested the effects of high-dosed prebiotic fibre on reward-related food decision-making in a randomised controlled within-subject cross-over study and assayed potential microbial and… Continue reading #Prebiotic #diet changes neural correlates of #food decision-making in #overweight adults: a randomised controlled within-subject cross-over trial 

Changes in #Coffee Intake, Added #Sugar and Long-Term #Weight Gain – Results from Three Large Prospective US Cohort Studies

BackgroundConsumption of both caffeinated and decaffeinated coffee has been reported to attenuate long-term weight gain. Whether the association between coffee consumption and weight gain depends on the addition of sugar, cream or coffee whitener remains unclear.ObjectiveWe aimed to study the associations between changes in coffee consumption, caffeine intake and weight changes by considering the addition… Continue reading Changes in #Coffee Intake, Added #Sugar and Long-Term #Weight Gain – Results from Three Large Prospective US Cohort Studies

Mechanisms of #weight loss-induced remission in people with #prediabetes: a post-hoc analysis of the randomised, controlled, multicentre Prediabetes Lifestyle Intervention Study (PLIS)

Background Remission of type 2 diabetes can occur as a result of weight loss and is characterised by liver fat and pancreas fat reduction and recovered insulin secretion. In this analysis, we aimed to investigate the mechanisms of weight loss- induced remission in people with prediabetes.MethodsIn this prespecified post-hoc analysis, weight loss-induced resolution of prediabetes… Continue reading Mechanisms of #weight loss-induced remission in people with #prediabetes: a post-hoc analysis of the randomised, controlled, multicentre Prediabetes Lifestyle Intervention Study (PLIS)

Effects of chronic #caffeine on patterns of #brain blood flow and behavior throughout the sleep–wake cycle in freely behaving mice 

Caffeine has significant effects on neurovascular activity and behavior throughout the sleep–wake cycle. We used a minimally invasive microchip/video system to continuously record effects of caffeine in the drinking water of freely behaving mice. Chronic caffeine shifted both rest and active phases by up to 2 h relative to the light–dark cycle in a dose-dependent fashion.… Continue reading Effects of chronic #caffeine on patterns of #brain blood flow and behavior throughout the sleep–wake cycle in freely behaving mice 

Dietary #Carbohydrate and #Fat Intakes and Risk of Mortality in the Japanese Population: the Japan Multi-Institutional Collaborative Cohort Study

BackgroundPrevious cohort studies have yielded contradictory findings regarding the associations of dietary carbohydrate and fat intakes with risks of mortality.ObjectivesWe examined long-term associations of carbohydrate and fat intakes with mortality.MethodsIn this cohort study, 34,893 men and 46,440 women aged 35–69 y (mean body mass index of 23.7 and 22.2 kg/m2, respectively) were followed up from the baseline survey (2004–2014)… Continue reading Dietary #Carbohydrate and #Fat Intakes and Risk of Mortality in the Japanese Population: the Japan Multi-Institutional Collaborative Cohort Study