Impact of #lifestyle moderate-to-vigorous #physical activity timing on #glycemic control in sedentary adults with #overweight/obesity and metabolic impairments

ObjectiveModerate-to-vigorous physical activity (MVPA) improves glucose levels; however, whether its timing affects daily glycemic control remains unclear. This study aims to investigate the impact of lifestyle MVPA timing on daily glycemic control in sedentary adults with overweight/obesity and metabolic impairments.MethodsA total of 186 adults (50% women; age, 46.8 [SD 6.2] years) with overweight/obesity (BMI, 32.9… Continue reading Impact of #lifestyle moderate-to-vigorous #physical activity timing on #glycemic control in sedentary adults with #overweight/obesity and metabolic impairments

#High-fat diet, #microbiome-gut-brain axis signaling, and #anxiety-like behavior in male rats

Obesity, associated with the intake of a high-fat diet (HFD), and anxiety are common among those living in modern urban societies. Recent studies suggest a role of microbiome-gut-brain axis signaling, including a role for brain serotonergic systems in the relationship between HFD and anxiety. Evidence suggests the gut microbiome and the serotonergic brain system together… Continue reading #High-fat diet, #microbiome-gut-brain axis signaling, and #anxiety-like behavior in male rats

Effects of #Cocoa Consumption on #Cardiometabolic Risk Markers: Meta-Analysis of Randomized Controlled Trials

Abstract: Background: We conducted a systematic review and meta-analysis to examine the effect of dietary intake of cocoa on anthropometric measurements, lipid and glycemic profiles, and blood pressure levels in adults, with and without comorbidities. Methods: The databases used were MEDLINE (PubMed), EMBASE, Web of Science, Cochrane, LILACS, and SciELO. The eligible studies were randomized… Continue reading Effects of #Cocoa Consumption on #Cardiometabolic Risk Markers: Meta-Analysis of Randomized Controlled Trials

#Overweight in #Adolescence and Young Adulthood in Association With Adult #Cerebrovascular Disease: The NFBC1966 Study

BACKGROUND:Risk factors for cerebrovascular disease in adulthood are well known. However, research on individuals’ risk factors throughout their life span has been limited. This prospective cohort study aims to determine the effect of body mass index (BMI) and its changes in adolescence and young adulthood on early onset cerebrovascular disease.METHODS:This study includes 10 491 people (5185… Continue reading #Overweight in #Adolescence and Young Adulthood in Association With Adult #Cerebrovascular Disease: The NFBC1966 Study

Divergent age-associated and metabolism-associated gut #microbiome signatures modulate #cardiovascular disease risk

Insight into associations between the gut microbiome with metabolism and aging is crucial for tailoring interventions to promote healthy longevity. In a discovery cohort of 10,207 individuals aged 40–93 years, we used 21 metabolic parameters to classify individuals into five clusters, termed metabolic multimorbidity clusters (MCs), that represent different metabolic subphenotypes. Compared to the cluster classified… Continue reading Divergent age-associated and metabolism-associated gut #microbiome signatures modulate #cardiovascular disease risk

Association between consumption of small #fish and all-cause #mortality among Japanese: the Japan Multi-Institutional Collaborative Cohort Study

Although small fish are an important source of micronutrients, the relationship between their intake and mortality remains unclear. This study aimed to clarify the association between intake of small fish and all-cause and cause-specific mortality.Design:We used the data from a cohort study in Japan. The frequency of the intake of small fish was assessed using… Continue reading Association between consumption of small #fish and all-cause #mortality among Japanese: the Japan Multi-Institutional Collaborative Cohort Study

#Sodium Intake and #Atopic Dermatitis

Question  Is a higher level of sodium intake associated with risk of atopic dermatitis (AD)?Findings  In this cross-sectional study of 215 832 adults from the UK Biobank cohort, a 1-g higher estimated 24-hour urine sodium excretion was associated with an 11% higher odds of AD diagnosis, 16% higher odds of active AD, and 11% higher odds of increasing… Continue reading #Sodium Intake and #Atopic Dermatitis

#Mediterranean #Diet Adherence and Risk of All-Cause #Mortality in #Women

Key PointsQuestion  Is adherence to the Mediterranean diet associated with lower mortality in a US female population, and if so, what are possible biological mechanisms? Findings  In this cohort study of 25 315 women followed up for 25 years, higher adherence to the Mediterranean diet was associated with a 23% reduced risk of all-cause mortality. Biomarkers of small… Continue reading #Mediterranean #Diet Adherence and Risk of All-Cause #Mortality in #Women

Adherence to the #low-fat diet pattern reduces the risk of #lung cancer in American adults aged 55 years and above: a prospective cohort study

ObjectivesThere is little evidence on the association between low-fat dietary patterns and lung cancer risk among middle-aged and older adults. To fill this gap, we comprehensively investigated the association of adherence to a low-fat diet (LFD) and intake of different fat components including saturated, monounsaturated, and polyunsaturated fatty acids with incidence of lung cancer and… Continue reading Adherence to the #low-fat diet pattern reduces the risk of #lung cancer in American adults aged 55 years and above: a prospective cohort study