Aims: To assess the relationship between #coffee consumption and all-cause mortality in heart failure (#HF ) patients, using data from the National Health and Nutrition Examination Survey (NHANES).Methods and results: We analyzed data from NHANES (2003-2018), including 915 participants with HF who reported daily caffeine intake. Participants were categorized into coffee consumption levels: zero, one,… Continue reading The Impact of Coffee Consumption on Mortality Among Patients With Heart Failure
Category: Diet
Evening snacks without increased nighttime caloric intake decrease fasting glucose in pregnant women with pregestational diabetes mellitus
ObjectiveTo investigate the association between chrononutrition and glycemic control parameters throughout the pregnancy in women with diabetes mellitus (DM).MethodsCross-sectional study with 117 pregnant women with pregestational DM. Food consumption was assessed using 24-h dietary recalls in the second and third trimesters of pregnancy. Chrononutrition parameters included number of eating episodes, eating pattern, mealtimes, and caloric… Continue reading Evening snacks without increased nighttime caloric intake decrease fasting glucose in pregnant women with pregestational diabetes mellitus
Pro-inflammatory dietary patterns are associated with increased pain and functional disability in sciatica: a hospital-based cross-sectional study
Background: #Sciatica is a common neuropathic pain condition associated with substantial functional disability. Emerging evidence suggests that #diet -induced inflammation may play a role in chronic pain development. However, the association between dietary inflammatory potential and clinical outcomes in sciatica remains unclear.Methods: In this cross-sectional study, we enrolled 598 patients diagnosed with sciatica from two… Continue reading Pro-inflammatory dietary patterns are associated with increased pain and functional disability in sciatica: a hospital-based cross-sectional study
Revisiting the Role of Vitamin D in Fracture Prevention in the Era of Mega-Trials
For decades, vitamin #D has been a cornerstone of preventive medicine. However, recent large-scale randomized controlled trials have failed to replicate the broad benefits previously observed in epidemiological studies, particularly with respect to fracture and fall prevention in vitamin D-replete populations. Moreover, growing evidence suggesting an increased fall risk associated with highdose bolus administration has… Continue reading Revisiting the Role of Vitamin D in Fracture Prevention in the Era of Mega-Trials
Female Underweight/Undernutrition Syndrome (FUS): An Emerging Health Concept in Premenopausal Women – Secondary Publication (English Translation of the Japanese Statement)
In Japan, approximately 20% of women in their twenties are #underweight (BMI < 18.5 kg/m2), representing one of the highest prevalences among developed nations. Underweight and undernutrition are associated with decreased bone mass, menstrual abnormalities, impaired glucose tolerance, sarcopenia-like changes, and systemic symptoms including depression and fatigue, significantly impacting health from young adulthood through the… Continue reading Female Underweight/Undernutrition Syndrome (FUS): An Emerging Health Concept in Premenopausal Women – Secondary Publication (English Translation of the Japanese Statement)
Comparison of nutrients and ultra-processed food consumption between different phenotypes defined by abdominal obesity and sarcopenia
Background: #Obesity, #sarcopenia, and sarcopenic obesity require effective nutritional strategies in public health.Methods: This cross-sectional study analyzed 535 adults aged 40–60 years in rural Korea. Participants were grouped by abdominal obesity (waist circumference ≥90 cm for men, ≥85 cm for women) and probable sarcopenia (handgrip strength ≤28 kg for men, ≤18 kg for women). Dietary intake was assessed using a… Continue reading Comparison of nutrients and ultra-processed food consumption between different phenotypes defined by abdominal obesity and sarcopenia
#Fasting boosts #breast cancer therapy efficacy via glucocorticoid activation
The majority of breast cancers are driven by oestrogen receptor-α (ERα) activation, and endocrine therapy represents the mainstay treatment for these patients1. However, resistance is common and tumours often progress after years of endocrine suppression2. Periodic fasting enhances the efficacy of standard endocrine therapy and delays acquired drug resistance, although the underlying mechanisms remain unclear3.… Continue reading #Fasting boosts #breast cancer therapy efficacy via glucocorticoid activation
The effects of glucagon-like peptide-1 receptor agonists (#GLP1-RAs ) on #alcohol -related outcomes: a systematic review and meta-analysis
Objective: To evaluate the effects of glucagon-like peptide-1 receptor agonists (GLP-1RAs) on alcohol-related outcomes in adults with or without alcohol use disorder (AUD).Methods: A systematic review and meta-analysis following PRISMA guidelines searched PubMed, Embase, and Cochrane Library up to May 3, 2025. Eligible studies included randomized controlled trials (RCTs) and observational studies assessing GLP-1RAs (e.g.,… Continue reading The effects of glucagon-like peptide-1 receptor agonists (#GLP1-RAs ) on #alcohol -related outcomes: a systematic review and meta-analysis
#Ultra-processed foods and human health: the main thesis and the evidence
This first paper in a three-part Lancet Series combines narrative and systematic reviews with original analyses and meta-analyses to assess three hypotheses concerning a dietary pattern based on ultra-processed foods. The first hypothesis—that this pattern is globally displacing long-established diets centred on whole foods and their culinary preparation as dishes and meals—is supported by decades… Continue reading #Ultra-processed foods and human health: the main thesis and the evidence
2 Medical News 