Our current understanding of immunity to pathogens suggests that anatomic coupling of antigens with danger signals is a required feature for the formation of immune memory. However, in the context of pathogen-independent inflammation, the stringency of this anatomical coupling is unclear. Here, we demonstrate that multiple modes of skin injury were sufficient to induce a… Continue reading #Skin damage signals mediate #allergic sensitization to spatially unlinked antigen
Category: Dermatology
#Tattoos as a risk factor for malignant #lymphoma: a population-based case–control study
BackgroundThe popularity of tattoos has increased dramatically over the last few decades. Tattoo ink often contains carcinogenic chemicals, e.g., primary aromatic amines, polycyclic aromatic hydrocarbons, and metals. The tattooing process invokes an immunologic response that causes translocation of tattoo ink from the injection site. Deposition of tattoo pigment in lymph nodes has been confirmed but the long-term… Continue reading #Tattoos as a risk factor for malignant #lymphoma: a population-based case–control study
#Urticaria and the risk of #cancer: a Danish population-based cohort study
BackgroundUrticaria has been tentatively linked to cancer, but epidemiological evidence supporting this link is sparse and conflicting. We therefore conducted a population-based cohort study using healthcare databases of the Danish population (January 1980–December 2022). We followed 87,507 people for a median of 10.1 years after first hospital contact for urticaria.ObjectivesTo examine associations of a hospital… Continue reading #Urticaria and the risk of #cancer: a Danish population-based cohort study
#Sodium Intake and #Atopic Dermatitis
Question Is a higher level of sodium intake associated with risk of atopic dermatitis (AD)?Findings In this cross-sectional study of 215 832 adults from the UK Biobank cohort, a 1-g higher estimated 24-hour urine sodium excretion was associated with an 11% higher odds of AD diagnosis, 16% higher odds of active AD, and 11% higher odds of increasing… Continue reading #Sodium Intake and #Atopic Dermatitis
A meta-analysis study on the association between #smoking and male pattern #hair loss
Smoking—which often refers to recreational consumption of the nicotine-containing tobacco—is deemed a risk factor for both the development of and worsening of androgenetic alopecia (AGA). However, there is no published meta-analysis study on the effect of smoking on AGA; so, we quantitatively synthesized the evidence base pertaining to the recreational activity and this form of… Continue reading A meta-analysis study on the association between #smoking and male pattern #hair loss
#ATOPIC DERMATITIS PATIENT EXPERIENCE WITH DISCUSSING AND ADDRESSING MENTAL HEALTH CONCERNS WITH ALLERGISTS
Atopic dermatitis (AD) is the most common form of eczema and has a significant, multidimensional burden of disease. Patients with AD have an increased likelihood of developing depression and anxiety, which is exacerbated when additional atopic comorbidities are present. Little is known about the patient experience with discussing or addressing mental health concerns with their… Continue reading #ATOPIC DERMATITIS PATIENT EXPERIENCE WITH DISCUSSING AND ADDRESSING MENTAL HEALTH CONCERNS WITH ALLERGISTS
Risk of #Inflammatory #Bowel Disease in Patients With #Atopic Dermatitis
Data on the association between atopic dermatitis (AD) and inflammatory bowel disease (IBD) are inconsistent. Few studies have examined the association of AD or AD severity with risk of ulcerative colitis (UC) and Crohn disease (CD) separately.Objectives To examine the risk of new-onset IBD, UC, and CD in children and adults with AD. Design, Setting, and… Continue reading Risk of #Inflammatory #Bowel Disease in Patients With #Atopic Dermatitis
Increased risk of osteoarthritis in patients with atopic disease
Objectives To determine the incidence of osteoarthrits (OA) in patients with atopic disease compared with matched non-exposed patients.Methods We conducted a retrospective cohort study with propensity score matching using claims data from Optum’s de-identified Clinformatics Data Mart (CDM) (January 2003 to June 2019) and electronic health record data from the Stanford Research Repository (STARR) (January 2010 to… Continue reading Increased risk of osteoarthritis in patients with atopic disease
Bioelectronic microfluidic wound healing: a platform for investigating direct current stimulation of injured cell collectives
Upon cutaneous injury, the human body naturally forms an electric field (EF) that acts as a guidance cue for relevant cellular and tissue repair and reorganization. However, the direct current (DC) flow imparted by this EF can be impacted by a variety of diseases. This work delves into the impact of DC stimulation on both… Continue reading Bioelectronic microfluidic wound healing: a platform for investigating direct current stimulation of injured cell collectives
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