We performed this study to investigate the association between sugar-sweetened beverage (SSB) consumption and male pattern hair loss (MPHL) in young men. We conducted this cross-sectional study from January to April 2022 in mainland China. Young people aged 18–45 years (n = 1951) were recruited from 31 provinces in China. We used a self-reported online survey… Continue reading The Association between Sugar-Sweetened Beverages and Male Pattern Hair Loss in Young Men
Category: Dermatology
Efficacy and Safety of a Fixed-Dose Clindamycin Phosphate 1.2%, Benzoyl Peroxide 3.1%, and Adapalene 0.15% Gel for Moderate-to-Severe Acne: A Randomized Phase II Study of the First Triple-Combination Drug
A three-pronged approach to acne treatment—combining an antibiotic, antibacterial, and retinoid—could provide greater efficacy and tolerability than single or dyad treatments, while potentially improving patient compliance and reducing antibiotic resistance.ObjectivesWe aimed to evaluate the efficacy and safety of triple-combination, fixed-dose topical clindamycin phosphate 1.2%/benzoyl peroxide (BPO) 3.1%/adapalene 0.15% (IDP-126) gel for the treatment of acne.MethodsIn… Continue reading Efficacy and Safety of a Fixed-Dose Clindamycin Phosphate 1.2%, Benzoyl Peroxide 3.1%, and Adapalene 0.15% Gel for Moderate-to-Severe Acne: A Randomized Phase II Study of the First Triple-Combination Drug
Efficacy of low-dose oral minoxidil in the management of anticancer therapy-induced alopecia in patients with breast cancer: A retrospective cohort study
To the Editor: Alopecia is feared by most patients undergoing systemic anticancer therapy for breast cancer because of its negative impact on quality of life.1 Currently, evidence regarding management of persistent chemotherapy-induced alopecia ( pCIA) and endocrine therapy-induced alopecia (EIA) in patients with breast cancer is lacking.2-4 Although previous studies demonstrated successful use of lowdose… Continue reading Efficacy of low-dose oral minoxidil in the management of anticancer therapy-induced alopecia in patients with breast cancer: A retrospective cohort study
Evaluation of the Safety and Effectiveness of Nutritional Supplements for Treating Hair LossA Systematic Review
Importance Despite the widespread use of nutritional supplements and dietary interventions for treating hair loss, the safety and effectiveness of available products remain unclear.Objective To evaluate and compile the findings of all dietary and nutritional interventions for treatment of hair loss among individuals without a known baseline nutritional deficiency.Evidence Review The MEDLINE, Embase, and CINAHL databases were searched… Continue reading Evaluation of the Safety and Effectiveness of Nutritional Supplements for Treating Hair LossA Systematic Review
Evaluation of the Safety and Effectiveness of Nutritional Supplements for Treating Hair LossA Systematic Review
Importance Despite the widespread use of nutritional supplements and dietary interventions for treating hair loss, the safety and effectiveness of available products remain unclear.Objective To evaluate and compile the findings of all dietary and nutritional interventions for treatment of hair loss among individuals without a known baseline nutritional deficiency.Evidence Review The MEDLINE, Embase, and CINAHL databases were searched… Continue reading Evaluation of the Safety and Effectiveness of Nutritional Supplements for Treating Hair LossA Systematic Review
Oral Herpes Zoster Infection Following COVID-19 Vaccination: A Report of Five Cases
Recently, two cases of oral herpes zoster (HZ) following COVID-19 vaccines were reported. It was suggested that COVID-19 vaccine-related oral HZ cases might be missed or misdiagnosed as stomatitis or isolated oral herpes. In this report, five cases of oral HZ following COVID-19 vaccinations are presented. Four cases were observed on the hard palate (V2),… Continue reading Oral Herpes Zoster Infection Following COVID-19 Vaccination: A Report of Five Cases
Alopecia areata following COVID-19 vaccination: vaccine-induced autoimmunity?
Dear Editor, We report a case of an 80-year-old man who came to our attention for a rapidly progressive loss of facial hair 7 days after the administration of the first dose of the BNT162b2 vaccine, an mRNA vaccine against SARS-CoV-2. He had no personal or family history of alopecia or autoimmunity. Before the vaccination, a… Continue reading Alopecia areata following COVID-19 vaccination: vaccine-induced autoimmunity?
Eczema is a shared risk factor for anxiety and depression: A meta-analysis and systematic review
Globally, anxiety and depression are the most common psychiatric disorders that add large burdens to individuals and society; however, the mechanisms underlying these disorders are unclear. Several studies have found that eczema is a shared risk factor for both these conditions. We identified and evaluated eligible observational studies from EMBASE and PubMed. In total, 20… Continue reading Eczema is a shared risk factor for anxiety and depression: A meta-analysis and systematic review
Two Phase 3 Trials of Baricitinib for Alopecia Areata
BACKGROUNDAlopecia areata is an autoimmune condition characterized by rapid hair loss in the scalp, eyebrows, and eyelashes, for which treatments are limited. Baricitinib, an oral, selective, reversible inhibitor of Janus kinases 1 and 2, may interrupt cytokine signaling implicated in the pathogenesis of alopecia areata. METHODSWe conducted two randomized, placebo-controlled, phase 3 trials (BRAVE-AA1 and… Continue reading Two Phase 3 Trials of Baricitinib for Alopecia Areata