Biologic therapies have emerged as effective treatments for chronic spontaneous #urticaria (CSU), a debilitating skin disease. However, real-world data on their use are limited. This retrospective descriptive study analyzes the time from diagnosis to biologic therapy initiation and the CSU-specific healthcare resource utilization (HCRU) among patients with ≥ 2 urticaria diagnoses or one urticaria and… Continue reading Healthcare Resource Utilization and Use of Biologics in Chronic Spontaneous Urticaria
Tag: urticaria
Immunological Basis of Chronic Spontaneous Urticaria: Immunoglobulin E and Beyond
Chronic spontaneous #urticaria (CSU) is associated with a substantial disease burden due to its prolonged course and significant impairment of quality of life. The diagnostic process for #CSU involves confirming the diagnosis itself and identifying disease phenotypes or endotypes, cofactors, and comorbid conditions, which may affect disease activity and severity. Immunoglobulin E (IgE) and non-IgE-mediated… Continue reading Immunological Basis of Chronic Spontaneous Urticaria: Immunoglobulin E and Beyond
Dupilumab in Patients With Chronic Spontaneous Urticaria: Phase 3 LIBERTY-CSU CUPID Randomized Clinical Trials
Importance: Chronic spontaneous #urticaria (CSU) is an inflammatory disease characterized by recurrent pruritic hives and/or #angioedema. Many patients with CSU remain symptomatic despite standard-of-care, histamine 1-receptor antagonist (H1-AH) treatment. Dupilumab blocks IL-4/IL-13 signaling and is approved in multiple disease states associated with type 2 inflammation. In the phase 3 LIBERTY-CSU CUPID-A trial, dupilumab significantly reduced… Continue reading Dupilumab in Patients With Chronic Spontaneous Urticaria: Phase 3 LIBERTY-CSU CUPID Randomized Clinical Trials
#Urticaria and the risk of #cancer: a Danish population-based cohort study
BackgroundUrticaria has been tentatively linked to cancer, but epidemiological evidence supporting this link is sparse and conflicting. We therefore conducted a population-based cohort study using healthcare databases of the Danish population (January 1980–December 2022). We followed 87,507 people for a median of 10.1 years after first hospital contact for urticaria.ObjectivesTo examine associations of a hospital… Continue reading #Urticaria and the risk of #cancer: a Danish population-based cohort study
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