Definition and diagnostic criteria of clinical #obesity

Current BMI-based measures of obesity can both underestimate and overestimate adiposity and provide inadequate information about health at the individual level, which undermines medically-sound approaches to health care and policy. This Commission sought to define clinical obesity as a condition of illness that, akin to the notion of chronic disease in other medical specialties, directly… Continue reading Definition and diagnostic criteria of clinical #obesity

Advancements in wearable #heart sounds devices for the monitoring of #cardiovascular diseases

Cardiovascular diseases remain a leading global cause of mortality, underscoring the urgent need for intelligent diagnostic tools to enhance early detection, prediction, diagnosis, prevention, treatment, and recovery. This demand has spurred the advancement of wearable and flexible technologies, revolutionizing continuous, noninvasive, and remote heart sound (HS) monitoring—a vital avenue for assessing heart activity. The conventional… Continue reading Advancements in wearable #heart sounds devices for the monitoring of #cardiovascular diseases

#Breakfast energy intake and dietary quality and trajectories of #cardiometabolic risk factors in older adults

Highlights•Eating 20−30% of daily energy in breakfast links to less adiposity in older adults.•It is also related to less triglycerides and more HDL cholesterol (HDL-C).•A high-quality breakfast is linked to better adiposity, HDL-C, and kidney function.•Healthy breakfast habits relate to healthy aging by improving heart risk factors. ObjectivesNot skipping breakfast is associated with a better… Continue reading #Breakfast energy intake and dietary quality and trajectories of #cardiometabolic risk factors in older adults

Better #diet quality is associated with reduced body #pain in adults regardless of adiposity: Findings from the Whyalla Intergenerational Study of Health

Highlights•Better diet quality had a direct (beneficial) effect on pain.•Higher consumption of core foods was related to less pain in women, but not men.•Adiposity did not mediate the relationship between diet quality and pain.•Strategies for pain management should consider diet quality. AbstractDietary intake has been associated with pain and physical function, but it is unclear… Continue reading Better #diet quality is associated with reduced body #pain in adults regardless of adiposity: Findings from the Whyalla Intergenerational Study of Health

The Role of Dietary #Magnesium in #Cardiovascular Disease

In the past 20 years, a large number of epidemiological studies, randomized controlled trials, and meta-analyses have found an inverse relationship between magnesium intake or serum magnesium and cardiovascular disease, indicating that low magnesium status is associated with hypertension, coronary artery calcification, stroke, ischemic heart disease, atrial fibrillation, heart failure, and cardiac mortality. Controlled metabolic… Continue reading The Role of Dietary #Magnesium in #Cardiovascular Disease

Restrictive versus Liberal #Transfusion in Myocardial #Infarction — A Patient-Level Meta-Analysis

BackgroundClinical guidelines have concluded that there are insufficient data to provide recommendations for the hemoglobin threshold for the use of red cell transfusion in patients with acute myocardial infarction (MI) and anemia. After the recent publication of the Myocardial Infarction and Transfusion (MINT) trial, we performed an individual patient-level data meta-analysis to evaluate the effect… Continue reading Restrictive versus Liberal #Transfusion in Myocardial #Infarction — A Patient-Level Meta-Analysis

Urinary #tartaric acid as a biomarker of #wine consumption and #cardiovascular risk: the PREDIMED trial

Background and AimsModerate wine consumption has been associated with lower cardiovascular disease (CVD) risk in older populations. However, wine consumption information through self-reports is prone to measurement errors inherent to subjective assessments. The aim of this study was to evaluate the association between urinary tartaric acid, an objective biomarker of wine consumption, and the rate… Continue reading Urinary #tartaric acid as a biomarker of #wine consumption and #cardiovascular risk: the PREDIMED trial

Long-Term #Aspirin vs #Clopidogrel After #Coronary Stenting by Bleeding Risk and Procedural Complexity

Question  What is the comparative effectiveness of clopidogrel vs aspirin monotherapy in the chronic maintenance period after percutaneous coronary intervention (PCI) according to bleeding risk and procedural complexity?Findings  In this post hoc analysis of the HOST-EXAM Extended clinical trial, clopidogrel monotherapy was associated with a reduction in thrombotic and bleeding risks compared with aspirin, regardless… Continue reading Long-Term #Aspirin vs #Clopidogrel After #Coronary Stenting by Bleeding Risk and Procedural Complexity

Device-measured vigorous intermittent lifestyle #physical activity (VILPA) and major adverse cardiovascular events: evidence of sex differences

Background Vigorous intermittent lifestyle physical activity (VILPA) refers to brief bouts of intense physical activity embedded into daily life.Objective To examine sex differences in the dose–response association of VILPA with major adverse cardiovascular events (MACE) and its subtypes.Methods Using multivariable-adjusted cubic splines, we examined the associations of daily VILPA duration with overall MACE and its… Continue reading Device-measured vigorous intermittent lifestyle #physical activity (VILPA) and major adverse cardiovascular events: evidence of sex differences