Studies of the association between ultraprocessed foods (UPF) and cardiovascular disease risk factors have been mainly focused on the adult population. This study examined the association between usual percentage of calories (%kcal) from UPF and the American Heart Association's seven cardiovascular health (CVH) metrics among U.S. adolescents aged 12–19 years. MethodsWe used data from the… Continue reading Relationship Between #Ultraprocessed Food Intake and #Cardiovascular Health Among U.S. Adolescents: Results From the National Health and Nutrition Examination Survey 2007–2018
Category: Cardiology
Impact of Sustained #Weight Loss on #Cardiometabolic Outcomes
Highlights•Sustained weight loss significantly lowers incidence of cardiometabolic outcomes.•Sustained weight loss significantly delays onset of cardiometabolic outcomes.•Greater weight loss significantly delays onset of cardiometabolic outcomes. Obesity increases the risk of developing type 2 diabetes, hypertension, and hyperlipidemia. We sought to determine the impact of obesity maintenance, weight regain, weight loss maintenance, and magnitudes of weight… Continue reading Impact of Sustained #Weight Loss on #Cardiometabolic Outcomes
#Environmental risk factors and #cardiovascular diseases: a comprehensive expert review
AbstractNon-communicable diseases (NCDs) are fatal for more than 38 million people each year and are thus the main contributors to the global burden of disease accounting for 70% of mortality. The majority of these deaths are caused by cardiovascular disease (CVD). The risk of NCDs is strongly associated with exposure to environmental stressors such as… Continue reading #Environmental risk factors and #cardiovascular diseases: a comprehensive expert review
Analysis of Respiratory #Fluoroquinolones and the Risk of Sudden #Cardiac Death Among Patients Receiving #Hemodialysis
Respiratory fluoroquinolone antibiotics are some of the most common medications with QT interval–prolonging potential prescribed to patients with hemodialysis-dependent kidney failure—individuals who have a very high risk of sudden cardiac death (SCD). To date, there have been no large-scale, population-specific studies evaluating the cardiac safety of respiratory fluoroquinolones in the hemodialysis population. Objective To investigate… Continue reading Analysis of Respiratory #Fluoroquinolones and the Risk of Sudden #Cardiac Death Among Patients Receiving #Hemodialysis
Incidence Rates and Predictors of Microvascular and Macrovascular Complications in Patients with Type 2 #Diabetes: Results from the Longitudinal Global DISCOVER Study
In a global prospective study of patients with relatively early-stage diabetes, microvascular and macrovascular complications were common and were associated with increased risk of subsequent hospitalization and death. •The strongest predictor of incident complications was the known atherosclerosis or heart failure at enrollment. •Poor glucose control and smoking were also associated with increased risk of… Continue reading Incidence Rates and Predictors of Microvascular and Macrovascular Complications in Patients with Type 2 #Diabetes: Results from the Longitudinal Global DISCOVER Study
Visit-to-visit fasting blood #glucose variability and lifetime risk of #cardiovascular disease: a prospective study
Previous studies suggested an adverse association between higher fasting blood glucose (FBG) variability and cardiovascular disease (CVD). Lifetime risk provides an absolute risk assessment during the remainder of an individual’s life. However, the association between FBG variability and the lifetime risk of CVD is uncertain. ObjectiveWe aimed to investigate the effect of the visit-to-visit FBG… Continue reading Visit-to-visit fasting blood #glucose variability and lifetime risk of #cardiovascular disease: a prospective study
Cardiovascular health, genetic predisposition, and lifetime risk of type 2 #diabetes
Data on the lifetime risk of type 2 diabetes (T2D) incidence across different cardiovascular health (CVH) categories are scarce. Moreover, it remains unclear whether a genetic predisposition modifies this association. Methods and resultsUsing data from the prospective population-based Rotterdam Study, a CVH score (body mass index, blood pressure, total cholesterol, smoking status, diet, and physical… Continue reading Cardiovascular health, genetic predisposition, and lifetime risk of type 2 #diabetes
Compensatory ion transport buffers daily protein #rhythms to regulate osmotic balance and cellular physiology
Between 6–20% of the cellular proteome is under circadian control and tunes mammalian cell function with daily environmental cycles. For cell viability, and to maintain volume within narrow limits, the daily variation in osmotic potential exerted by changes in the soluble proteome must be counterbalanced. The mechanisms and consequences of this osmotic compensation have not… Continue reading Compensatory ion transport buffers daily protein #rhythms to regulate osmotic balance and cellular physiology
Cardiac #radiotherapy induces electrical conduction reprogramming in the absence of transmural fibrosis
Cardiac radiotherapy (RT) may be effective in treating heart failure (HF) patients with refractory ventricular tachycardia (VT). The previously proposed mechanism of radiation-induced fibrosis does not explain the rapidity and magnitude with which VT reduction occurs clinically. Here, we demonstrate in hearts from RT patients that radiation does not achieve transmural fibrosis within the timeframe… Continue reading Cardiac #radiotherapy induces electrical conduction reprogramming in the absence of transmural fibrosis