Incidence of adverse #cardiovascular events in patients with #insomnia: A systematic review and meta-analysis of real-world data

Insomnia is a prevalent sleeping disorder associated with increasing cardiovascular (CV) mortality and morbidity. However, data incorporating recent clinical studies evaluating these outcomes is scarce. Hence, we aimed to investigate the association of insomnia with CV mortality, myocardial infarction (MI), all-cause mortality, and incidence of CV disease by conducting the first-ever meta-analysis of real-world data… Continue reading Incidence of adverse #cardiovascular events in patients with #insomnia: A systematic review and meta-analysis of real-world data

Psychosocial #Stressors at #Work and #Coronary Heart Disease Risk in Men and Women: 18-Year Prospective Cohort Study of Combined Exposures

Psychosocial stressors at work, like job strain and effort-reward imbalance (ERI), can increase coronary heart disease (CHD) risk. ERI indicates an imbalance between the effort and received rewards. Evidence about the adverse effect of combined exposure to these work stressors on CHD risk is scarce. This study examines the separate and combined effect of job… Continue reading Psychosocial #Stressors at #Work and #Coronary Heart Disease Risk in Men and Women: 18-Year Prospective Cohort Study of Combined Exposures

Seated And Supine Blood #Pressure And Risk Of #Cardiovascular Disease And Mortality From The Atherosclerosis Risk In Communities Study

Background Hypertension (HTN) while asleep is strongly associated with cardiovascular disease (CVD) and death. Whether HTN while supine in clinic is a risk factor for CVD independent of seated BP remains unknown.Objectives To determine the relationship between supine HTN and adverse CVD.Methods The Atherosclerosis Risk in Communities (ARIC) Study measured supine and seated BP during visit 1 (1987-1989).… Continue reading Seated And Supine Blood #Pressure And Risk Of #Cardiovascular Disease And Mortality From The Atherosclerosis Risk In Communities Study

#Dementia Risk of Direct Oral Anticoagulants Versus Warfarin for Atrial #Fibrillation: Systematic Review and Meta-Analysis

BackgroundDirect-acting oral anticoagulants (DOACs) have demonstrated superior efficacy in preventing stroke and death compared with warfarin in patients with atrial fibrillation (AF), but their influence on dementia risk remains unclear.ObjectivesThe purpose of this study was to evaluate the relative risks of dementia in DOAC vs warfarin in patients with AF.MethodsAn electronic literature search was conducted… Continue reading #Dementia Risk of Direct Oral Anticoagulants Versus Warfarin for Atrial #Fibrillation: Systematic Review and Meta-Analysis

Stress test abnormalities reveal more than just cardiovascular risks, Mayo Clinic study finds

The treadmill exercise test with electrocardiogram (ECG), also known as an exercise stress test, is one of the most familiar tests in medicine. While exercise testing typically is focused on diagnosing coronary artery disease, a recent study from Mayo Clinic finds that exercise test abnormalities, such as low functional aerobic capacity, predicted non-cardiovascular causes of death such as… Continue reading Stress test abnormalities reveal more than just cardiovascular risks, Mayo Clinic study finds

Warning symptoms associated with imminent sudden #cardiac arrest: a population-based case-control study with external validation

BackgroundSudden cardiac arrest is a global public health problem with a mortality rate of more than 90%. Prearrest warning symptoms could be harnessed using digital technology to potentially improve survival outcomes. We aimed to estimate the strength of association between symptoms and imminent sudden cardiac arrest.MethodsWe conducted a case-control study of individuals with sudden cardiac… Continue reading Warning symptoms associated with imminent sudden #cardiac arrest: a population-based case-control study with external validation

Recovery #sleep following sleep restriction is insufficient to return elevated daytime heart #rate and systolic blood #pressure to baseline levels

Objective Sleep restriction alters daytime cardiac activity, including elevating heart rate (HR) and blood pressure (BP). There is minimal research on the cumulative effects of sleep loss and the response after subsequent recovery sleep on HR and BP. This study examined patterns of HR and BP across baseline, sleep restriction, and recovery conditions using multiple daytime cardiac… Continue reading Recovery #sleep following sleep restriction is insufficient to return elevated daytime heart #rate and systolic blood #pressure to baseline levels

Trajectories of #renal biomarkers and new-onset #heart failure in the general population: Findings from the PREVEND study

Renal dysfunction is one of the most critical risk factors for developing heart failure (HF). However, the association between repeated measures of renal function and incident HF remains unclear. Therefore, this study investigated the longitudinal trajectories of urinary albumin excretion (UAE) and serum creatinine and their association with new-onset HF and all-cause mortality.Methods and resultsUsing… Continue reading Trajectories of #renal biomarkers and new-onset #heart failure in the general population: Findings from the PREVEND study

Prospective Associations of Different Combinations of #Aerobic and #Muscle-Strengthening Activity With All-Cause, #Cardiovascular, and Cancer Mortality

Studies examining the associations of different combinations of intensity-specific aerobic and muscle strengthening activity (MSA) with all-cause and cause-specific mortality are scarce; the few available estimates are disparate.Objective  To examine the prospective associations of different combinations of moderate aerobic physical activity (MPA), vigorous aerobic physical activity (VPA), and MSA with all-cause, cardiovascular (CVD), and cancer mortality.Design,… Continue reading Prospective Associations of Different Combinations of #Aerobic and #Muscle-Strengthening Activity With All-Cause, #Cardiovascular, and Cancer Mortality