To investigate the association between mobile phone exposure and semen parameters.A nationwide cross-sectional study.SettingAndrology laboratories in close proximity to 6 army recruitment centers.PatientsIn total, 2886 men from the general Swiss population, 18–22 years old, were recruited between 2005 and 2018 during military conscription.InterventionParticipants delivered a semen sample and completed a questionnaire on health and lifestyle,… Continue reading Association between self-reported mobile #phone use and the #semen quality of young men
Author: aledopress
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Polygenic predisposition, #sleep duration, and #depression: evidence from a prospective population-based cohort
Suboptimal sleep durations and depression frequently cooccur. Short-sleep and long-sleep are commonly thought of as symptoms of depression, but a growing literature suggests that they may be prodromal. While each represents a process of mutual influence, the directionality between them remains unclear. Using polygenic scores (PGS), we investigate the prospective direction involved in suboptimal sleep… Continue reading Polygenic predisposition, #sleep duration, and #depression: evidence from a prospective population-based cohort
Dietary #Sodium Intake and Risk of Incident Type 2 #Diabetes
ObjectiveTo fill the knowledge gap of the relation between long-term dietary sodium intake and type 2 diabetes (T2D), we evaluate the association between the frequency of adding salt to foods, a surrogate marker for evaluating the long-term sodium intake, and incident T2D risk.MethodsA total of 402,982 participants from UK Biobank (March 13, 2006 – October… Continue reading Dietary #Sodium Intake and Risk of Incident Type 2 #Diabetes
A quarter of US medical students consider quitting school and most may not treat patients: new survey
Among the next generation of doctors, many are considering quitting medical school even before donning their long white coats. A quarter of all medical students in the United States might quit school. That’s according to a new report from Elsevier Health, which surveyed students to get their perspectives on education, career plans and expectations for… Continue reading A quarter of US medical students consider quitting school and most may not treat patients: new survey
Relationship of Daily #Step Counts to All-Cause #Mortality and #Cardiovascular Events
Background The minimal and optimal daily step counts for health improvements remain unclear. Objectives A meta-analysis was performed to quantify dose-response associations of objectively measured step count metrics in the general population. Methods Electronic databases were searched from inception to October 2022. Primary outcomes included all-cause mortality and incident cardiovascular disease (CVD). Study results were… Continue reading Relationship of Daily #Step Counts to All-Cause #Mortality and #Cardiovascular Events
Designing and computational analyzing of chimeric long-lasting #GLP-1 receptor agonists for type 2 #diabetes
Glucagon-like peptide-1 (GLP-1) is an intestinally derived incretin that plays a vital role in engineering the biological circuit involved in treating type 2 diabetes. Exceedingly short half-life (1–2 min) of GLP-1 limits its therapeutic applicability, and the implication of its new variants is under question. Since albumin-binding DARPin as a mimetic molecule has been reported to… Continue reading Designing and computational analyzing of chimeric long-lasting #GLP-1 receptor agonists for type 2 #diabetes
Untargeted metabolomic analysis investigating links between unprocessed red #meat intake and markers of #inflammation
BackgroundWhether red meat consumption is associated with higher inflammation or confounded by increased adiposity remains unclear. Plasma metabolites capture the effects of diet after food is processed, digested, and absorbed, and correlate with markers of inflammation, so they can help clarify diet-health relationships.ObjectiveTo identify whether any metabolites associated with red meat intake are also associated… Continue reading Untargeted metabolomic analysis investigating links between unprocessed red #meat intake and markers of #inflammation
Effect of aerobic #exercise on #erectile function: systematic review and meta-analysis of randomized controlled trials
The health benefits of regular aerobic exercise are well established, although there is limited high-quality evidence regarding its impact on erectile function.AimTo determine the effect of aerobic exercise on erectile function in men and to identify factors that may influence this effect.MethodsThis systematic review and meta-analysis included randomized controlled trials that evaluated the effects of… Continue reading Effect of aerobic #exercise on #erectile function: systematic review and meta-analysis of randomized controlled trials
The endocannabinoid N-arachidonoyl dopamine is critical for #hyperalgesia induced by chronic #sleep disruption
Chronic pain is highly prevalent and is linked to a broad range of comorbidities, including sleep disorders. Epidemiological and clinical evidence suggests that chronic sleep disruption (CSD) leads to heightened pain sensitivity, referred to as CSD-induced hyperalgesia. However, the underlying mechanisms are unclear. The thalamic reticular nucleus (TRN) has unique integrative functions in sensory processing,… Continue reading The endocannabinoid N-arachidonoyl dopamine is critical for #hyperalgesia induced by chronic #sleep disruption
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