Question Does the use of a reduced-sodium, added-potassium salt substitute vs regular salt decrease the risk of stroke recurrence and death in patients with a history of stroke?Findings In this prespecified subgroup analysis of the Salt Substitute and Stroke Study (SSaSS) trial involving 15 249 patients with stroke, the use of a salt substitute led… Continue reading Salt Substitution and Recurrent #Stroke and DeathA Randomized Clinical Trial
Tag: stroke
#Retinal vascular fingerprints predict incident #stroke: findings from the UK Biobank cohort study
Objective To investigate the associations between a comprehensive set of retinal vascular parameters and incident stroke to unveil new associations and explore its predictive power for stroke risk.Methods Retinal vascular parameters were extracted from the UK Biobank fundus images using the Retina-based Microvascular Health Assessment System. We used Cox regression analysis, adjusted for traditional risk… Continue reading #Retinal vascular fingerprints predict incident #stroke: findings from the UK Biobank cohort study
The predictive validity of a #Brain Care Score for late-life #depression and a composite outcome of #dementia, #stroke, and late-life #depression: data from the UK Biobank cohort
Introduction: The 21-point Brain Care Score (BCS) is a novel tool designed to motivate individuals and care providers to take action to reduce the risk of stroke and dementia by encouraging lifestyle changes. Given that late-life depression is increasingly recognized to share risk factors with stroke and dementia, and is an important clinical endpoint for brain… Continue reading The predictive validity of a #Brain Care Score for late-life #depression and a composite outcome of #dementia, #stroke, and late-life #depression: data from the UK Biobank cohort
Recurrent Ischemic #Stroke in Patients With Atrial #Fibrillation While Receiving Oral Anticoagulants
Importance Patients with atrial fibrillation (AF) can have an ischemic stroke (IS) despite oral anticoagulant (OAC) treatment. Knowledge regarding the association between OAC discontinuation and the subsequent risk of recurrent IS in patients with AF is limited.Objectives To determine the risk of recurrent IS in patients with AF receiving OAC and to evaluate the association between OAC… Continue reading Recurrent Ischemic #Stroke in Patients With Atrial #Fibrillation While Receiving Oral Anticoagulants
#Overweight in #Adolescence and Young Adulthood in Association With Adult #Cerebrovascular Disease: The NFBC1966 Study
BACKGROUND:Risk factors for cerebrovascular disease in adulthood are well known. However, research on individuals’ risk factors throughout their life span has been limited. This prospective cohort study aims to determine the effect of body mass index (BMI) and its changes in adolescence and young adulthood on early onset cerebrovascular disease.METHODS:This study includes 10 491 people (5185… Continue reading #Overweight in #Adolescence and Young Adulthood in Association With Adult #Cerebrovascular Disease: The NFBC1966 Study
#Glucagon-like peptide-1 receptor agonists and #stroke: A systematic review and meta-analysis of #cardiovascular outcome trials
Background:In patients surviving stroke, approximately 15% and 60% exhibit concurrent diabetes mellitus and overweight/obesity, respectively, necessitating heightened secondary prevention efforts. Despite glucagon-like peptide-1 receptor agonists (GLP-1 RAs) demonstrating improved outcomes for those with diabetes mellitus or obesity, their underutilization persists among eligible individuals. This systematic review and meta-analysis investigated the impact of GLP-1 RAs on… Continue reading #Glucagon-like peptide-1 receptor agonists and #stroke: A systematic review and meta-analysis of #cardiovascular outcome trials
Sleep #Apnea and Incident #Stroke in a National Cohort of Black and White Adults
Background and ObjectivesRacial/ethnic differences have been documented in the relationship between obstructive sleep apnea (OSA) and stroke incidence, yet racial differences in OSA symptoms or treatment and their relationship with stroke incidence are underexplored and may contribute to stroke disparities. We comprehensively examined OSA symptoms and their relationships to stroke incidence by race/ethnicity.MethodsData were collected… Continue reading Sleep #Apnea and Incident #Stroke in a National Cohort of Black and White Adults
Low-Dose #Aspirin and the Risk of #Stroke and Intracerebral #Bleeding in Healthy Older People Secondary Analysis of a Randomized Clinical Trial
Low-dose aspirin has been widely used for primary and secondary prevention of stroke. The balance between potential reduction of ischemic stroke events and increased intracranial bleeding has not been established in older individuals.Objective To establish the risks of ischemic stroke and intracranial bleeding among healthy older people receiving daily low-dose aspirin.Design, Setting, and Participants This secondary analysis… Continue reading Low-Dose #Aspirin and the Risk of #Stroke and Intracerebral #Bleeding in Healthy Older People Secondary Analysis of a Randomized Clinical Trial
The third Intensive Care Bundle with Blood Pressure Reduction in Acute Cerebral Haemorrhage Trial (INTERACT3): an international, stepped wedge cluster randomised controlled trial
Early control of elevated blood pressure is the most promising treatment for acute intracerebral haemorrhage. We aimed to establish whether implementing a goal-directed care bundle incorporating protocols for early intensive blood pressure lowering and management algorithms for hyperglycaemia, pyrexia, and abnormal anticoagulation, implemented in a hospital setting, could improve outcomes for patients with acute spontaneous… Continue reading The third Intensive Care Bundle with Blood Pressure Reduction in Acute Cerebral Haemorrhage Trial (INTERACT3): an international, stepped wedge cluster randomised controlled trial
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