Sleep difficulties have been implicated in the development and progression of dementia and in all-cause mortality. This study examines the relationship between sleep difficulties, incident dementia and all-cause mortality over 8 years of follow-up among a nationally representative sample of older (≥65 years) adults in the United States. We used data collected from the National… Continue reading #Sleep difficulties, incident #dementia and all-cause mortality among older adults across 8 years: Findings from the National Health and Aging Trends Study
Tag: sleep
Genetically Proxied Diurnal Preference, #Sleep Timing, and Risk of Major #Depressive Disorder
Morning diurnal preference is associated with reduced risk of major depressive disorder (MDD); however, causality in this association is uncertain. Objective To examine the association of genetically proxied morning diurnal preference with depression risk using mendelian randomization. Design, Setting, and Participants This 2-sample mendelian randomization study used summary-level genetic associations with diurnal preference and MDD.… Continue reading Genetically Proxied Diurnal Preference, #Sleep Timing, and Risk of Major #Depressive Disorder
The relationship between duration and quality of #sleep and upper #respiratory tract infections: a systematic review
Upper respiratory tract infections (URTIs) are common, mostly self-limiting, but result in inappropriate antibiotic prescriptions. Poor sleep is cited as a factor predisposing to URTIs, but the evidence is unclear. ObjectiveTo systematically review whether sleep duration and quality influence the frequency and duration of URTIs. MethodsThree databases and bibliographies of included papers were searched for… Continue reading The relationship between duration and quality of #sleep and upper #respiratory tract infections: a systematic review
Association between self‐reported night #sleep duration and #cognitive function among older adults with intact global cognition
The purpose of this study was to clarify the association between self‐reported night sleep duration and cognitive functions such as word memory, story memory, attention, executive function, and processing speed of older adults with normal global cognitive function. Methods A total of 241 functionally independent older adults (mean age, 75.5 ± 6.4 years) participated in… Continue reading Association between self‐reported night #sleep duration and #cognitive function among older adults with intact global cognition
Gut #microbiota depletion by chronic #antibiotic treatment alters the sleep/wake architecture and #sleep EEG power spectra in mice
Dysbiosis of the gut microbiota affects physiological processes, including brain functions, by altering the intestinal metabolism. Here we examined the effects of the gut microbiota on sleep/wake regulation. C57BL/6 male mice were treated with broad-spectrum antibiotics for 4 weeks to deplete their gut microbiota. Metabolome profiling of cecal contents in antibiotic-induced microbiota-depleted (AIMD) and control… Continue reading Gut #microbiota depletion by chronic #antibiotic treatment alters the sleep/wake architecture and #sleep EEG power spectra in mice
Assessment of Physician #Sleep and Wellness, #Burnout, and Clinically Significant Medical Errors
Sleep-related impairment in physicians is an occupational hazard associated with long and sometimes unpredictable work hours and may contribute to burnout and self-reported clinically significant medical error.. ..Of all physicians invited to participate in the survey, 7700 of 19 384 attending physicians (40%) and 3695 of 7257 house staff physicians (51%) completed sleep-related impairment items, including… Continue reading Assessment of Physician #Sleep and Wellness, #Burnout, and Clinically Significant Medical Errors
Gut #microbiota depletion by chronic antibiotic treatment alters the #sleep/wake architecture and sleep #EEG power spectra in mice
Dysbiosis of the gut microbiota affects physiological processes, including brain functions, by altering the intestinal metabolism. Here we examined the effects of the gut microbiota on sleep/wake regulation. C57BL/6 male mice were treated with broad-spectrum antibiotics for 4 weeks to deplete their gut microbiota. Metabolome profiling of cecal contents in antibiotic-induced microbiota-depleted (AIMD) and control… Continue reading Gut #microbiota depletion by chronic antibiotic treatment alters the #sleep/wake architecture and sleep #EEG power spectra in mice
Partial and Total #Sleep Deprivation Interferes with Neural Correlates of Consolidation of #Fear Extinction #Memory
We assessed the impact of total and partial sleep loss on neural correlates of fear conditioning and extinction learning and recall in healthy young adults. Methods Participants (56.3% female, age 24.8±3.4) were randomized to a night of normal sleep (NS, n=48), sleep restriction (SR, n=53), or sleep deprivation (SD, n=53). All completed fear conditioning and… Continue reading Partial and Total #Sleep Deprivation Interferes with Neural Correlates of Consolidation of #Fear Extinction #Memory
Losing Control: #Sleep Deprivation Impairs the Suppression of Unwanted #Thoughts
Unwanted memories often enter conscious awareness when individuals confront reminders. People vary widely in their talents at suppressing such memory intrusions; however, the factors that govern suppression ability are poorly understood. We tested the hypothesis that successful memory control requires sleep. Following overnight sleep or total sleep deprivation, participants attempted to suppress intrusions of emotionally… Continue reading Losing Control: #Sleep Deprivation Impairs the Suppression of Unwanted #Thoughts
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