#Sedentary Behavior and #Cardiac Events and Mortality After Hospitalization for Acute #Coronary Syndrome Symptoms: A Prospective Study

Patients hospitalized with symptoms of acute coronary syndrome remain at high risk for adverse events postdischarge, highlighting a need for modifiable therapeutic targets. The role of sedentary behavior in this risk and the potential benefits of replacing sedentary time with other activities remain unclear. This study examined the association between sedentary behavior and 1-year cardiac… Continue reading #Sedentary Behavior and #Cardiac Events and Mortality After Hospitalization for Acute #Coronary Syndrome Symptoms: A Prospective Study

Increased #sedentary behavior is associated with #neurodegeneration and worse cognition in older adults over a 7-year period despite high levels of physical activity

INTRODUCTIONSedentary behavior may be a modifiable risk factor for Alzheimer's disease (AD). We examined how sedentary behavior relates to longitudinal brain structure and cognitive changes in older adults.METHODSVanderbilt Memory and Aging Project participants (n = 404) completed actigraphy (7 days), neuropsychological assessment, and 3T brain MRI over a 7-year period. Cross-sectional and longitudinal linear regressions… Continue reading Increased #sedentary behavior is associated with #neurodegeneration and worse cognition in older adults over a 7-year period despite high levels of physical activity

Accelerometer-Measured #Sedentary Behavior and Risk of Future #Cardiovascular Disease

BackgroundBeyond serving as a marker for insufficient physical activity, sedentary behavior may directly affect future cardiovascular (CV) disease risk.ObjectivesThis study sought to examine associations between accelerometer-measured sedentary behavior with risk of specific CV outcomes, including potential relations with moderate to vigorous physical activity (MVPA).MethodsAmong participants of the UK Biobank prospective cohort study, we fit Cox… Continue reading Accelerometer-Measured #Sedentary Behavior and Risk of Future #Cardiovascular Disease

Prospective Associations of Accelerometer‐Measured Machine‐Learned #Sedentary Behavior With Death Among Older Women: The OPACH Study

BackgroundSedentary behavior is a recognized mortality risk factor. The novel and validated convolutional neural network hip accelerometer posture algorithm highly accurately classifies sitting and postural changes compared with accelerometer count cut points. We examined the prospective associations of convolutional neural network hip accelerometer posture–classified total sitting time and mean sitting bout duration with all‐cause and… Continue reading Prospective Associations of Accelerometer‐Measured Machine‐Learned #Sedentary Behavior With Death Among Older Women: The OPACH Study

The Cost of Inaction on Physical Inactivity to Healthcare Systems

Background: Physical inactivity (PI) is an important modifiable risk factor for noncommunicable diseases (NCDs) and mental health conditions. Estimating the public healthcare costs associated with these diseases due to PI will help policymakers to prioritise investment in policy actions to promote and enable more people to be more active.Methods: We used a population attributable fraction… Continue reading The Cost of Inaction on Physical Inactivity to Healthcare Systems

Association of Accelerometer-Measured Sedentary Time and Physical Activity With Risk of Stroke Among US Adults

Importance The amount and intensity of physical activity required to prevent stroke are yet to be fully determined because of previous reliance on self-reporting measures. Furthermore, the association between objectively measured time spent being sedentary as an independent risk factor for stroke is unknown. Objective To investigate the associations of accelerometer-measured sedentary time and physical… Continue reading Association of Accelerometer-Measured Sedentary Time and Physical Activity With Risk of Stroke Among US Adults

Prospective Analyses of Sedentary Behavior in Relation to Risk of Ovarian Cancer

To examine the association of sedentary behavior with risk of ovarian cancer overall, by tumor subtype, and by participant characteristics in the Nurses’ Health Study (NHS) and NHSII. A total of 69,558 NHS (1992-2016) and 104,130 NHSII (1991-2015) participants were included in analysis who reported sitting time at home, work, and watching television, which included… Continue reading Prospective Analyses of Sedentary Behavior in Relation to Risk of Ovarian Cancer

Association of Daily Sitting Time and Leisure-Time Physical Activity With Survival Among US Cancer Survivors

Objective To examine the independent and joint associations of daily sitting time and leisure-time physical activity with mortality outcomes among cancer survivors. Design, Setting, and Participants A prospective cohort of a nationally representative sample of cancer survivors, age 40 years or older (n = 1535; weighted population, 14 002 666), from the US National Health and Nutrition Examination Survey… Continue reading Association of Daily Sitting Time and Leisure-Time Physical Activity With Survival Among US Cancer Survivors

#Pain and fatigue are longitudinally and bi-directionally associated with more #sedentary time and less standing time in #rheumatoid arthritis

The aims of this study were to examine the longitudinal and bi-directional associations of pain and fatigue with sedentary, standing and stepping time in RA. Methods People living with RA undertook identical assessments at baseline (T1, n = 104) and 6-month follow-up (T2, n = 54). Participants completed physical measures (e.g. height, weight, BMI) and routine clinical assessments to… Continue reading #Pain and fatigue are longitudinally and bi-directionally associated with more #sedentary time and less standing time in #rheumatoid arthritis