Background/objective: The relationship between frailty and sarcopenia is well-known in older adults, but the factors associated with frailty were not adequately investigated. This study aimed to investigate the relationship between frailty levels and balance, fall risk, and kinesiophobia in older adults with primary sarcopenia and to compare them by sex.Methods: This cross-sectional study included 68… Continue reading Impact of #frailty on balance, fall risk, and kinesiophobia in #sarcopenic elderly
Tag: sarcopenia
#Amino acid metabolites as potential circulating biomarkers for #sarcopenia
Sarcopenia, characterized by the loss of muscle mass and strength, is a multifactorial disorder, including metabolic disturbance. Plasma amino acids (AAs) regulate muscle protein synthesis and breakdown. This study evaluated plasma AA metabolites as potential biomarkers for sarcopenia using metabolomic analysis. We assessed 31 AA metabo lites in an age-matched discovery cohort (72 men, 36… Continue reading #Amino acid metabolites as potential circulating biomarkers for #sarcopenia
#Sarcopenia and Sarcopenic #Obesity and Mortality Among Older People
Sarcopenia and obesity are 2 global concerns associated with adverse health outcomes in older people. Evidence on the population-based prevalence of the combination of sarcopenia with obesity (sarcopenic obesity [SO]) and its association with mortality are still limited.Objective To investigate the prevalence of sarcopenia and SO and their association with all-cause mortality.Design, Setting, and Participants This large-scale,… Continue reading #Sarcopenia and Sarcopenic #Obesity and Mortality Among Older People
Socioeconomic Disadvantage is Associated with Probable Sarcopenia in Community-Dwelling Older Adults: Findings from the English Longitudinal Study of Ageing
BackgroundSarcopenia is characterized by the accelerated loss of muscle strength, mass, and function in aging. The disease is a major public health issue with emerging evidence of a disproportionate burden in areas of socioeconomic disadvantage. ObjectivesTo estimate the prevalence of probable sarcopenia overall, and according to Socioeconomic Position (SEP). To explore the association between markers… Continue reading Socioeconomic Disadvantage is Associated with Probable Sarcopenia in Community-Dwelling Older Adults: Findings from the English Longitudinal Study of Ageing
Low #muscle mass in #older adults and mortality: A systematic review and meta-analysis
Sarcopenia comprises a loss of muscle function and muscle mass. So far, the association between the later and mortality in older adults is inconsistent. A meta-analysis was performed to assess whether muscle mass measured by appendicular skeletal muscle mass index (ASMI) is associated with higher mortality in older adults. Articles of interest were searched for… Continue reading Low #muscle mass in #older adults and mortality: A systematic review and meta-analysis
Number of #teeth and masticatory function are associated with #sarcopenia and #diabetes mellitus status among community-dwelling older adults: A Shimane CoHRE study
We aimed to examine the number of teeth and masticatory function as oral health indices and clarify their roles in the pathogenesis of sarcopenia and diabetes mellitus in community-dwelling older adults. Subjects and methodsThis cross-sectional study was conducted with 635 older adults in Ohnan, Shimane Prefecture, in rural Japan. The number of teeth and masticatory… Continue reading Number of #teeth and masticatory function are associated with #sarcopenia and #diabetes mellitus status among community-dwelling older adults: A Shimane CoHRE study
#Sarcopenia is independently associated with #parietal atrophy in older adults
Highlights•Sarcopenia was common in old adults living in a retirement community (46.1%). •Sarcopenia had moderate-severe global cortical, parietal and medial temporal atrophy. •Sarcopenia is significantly associated with parietal atrophy in older adults. •Age had a significant relationship with global cortical and medial temporal atrophy. AbstractIntroductionAs populations age, sarcopenia becomes a major health problem among adults… Continue reading #Sarcopenia is independently associated with #parietal atrophy in older adults
Prevalence and clinical implications of #sarcopenic obesity in patients with solid tumours of the respiratory and gastrointestinal tracts: a population-based study
Emerging evidence on body composition suggests that sarcopenic obesity (obesity with depleted muscle mass) might be predictive of morbidity and mortality in non-malignant disease and also of toxicity to chemotherapy.. ..Available lumbar CT images of the obese patients were analysed for total skeletal muscle cross-sectional area; these values were also used to estimate total body… Continue reading Prevalence and clinical implications of #sarcopenic obesity in patients with solid tumours of the respiratory and gastrointestinal tracts: a population-based study
Associations between Skeletal #Muscle and #Myocardium in Aging: A Syndrome of “Cardio‐Sarcopenia”?
..We hypothesize that among aging adults with sarcopenia, alterations in myocardial structure and/or function may exist, resulting in a syndrome of “cardio‐sarcopenia.” ..Participants with sarcopenia had smaller left ventricular (LV) sizes (lower LV internal diameter end diastole (4.1 ± .7 vs 4.5 ± .6 cm; P < .0001), lower LV internal diameter end systole (2.3 ± .5 vs 2.5 ± .4 cm; P = .010),… Continue reading Associations between Skeletal #Muscle and #Myocardium in Aging: A Syndrome of “Cardio‐Sarcopenia”?
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