Quantifying asymptomatic infection and transmission of #COVID-19 in New York City using observed cases, serology, and testing capacity

The contributions of asymptomatic infections to herd immunity and community transmission are key to the resurgence and control of COVID-19, but are difficult to estimate using current models that ignore changes in testing capacity. Using a model that incorporates daily testing information fit to the case and serology data from New York City, we show… Continue reading Quantifying asymptomatic infection and transmission of #COVID-19 in New York City using observed cases, serology, and testing capacity

Decline in Covid-19 Hospitalisation Growth Associated With Statewide Mask Mandates

What is already known about this topic? Wearing masks is recommended to mitigate the spread of COVID-19. What is added by this report? During March 22–October 17, 2020, 10 sites participating in the COVID-19–Associated Hospitalization Surveillance Network in states with statewide mask mandates reported a decline in weekly COVID-19–associated hospitalization growth rates by up to… Continue reading Decline in Covid-19 Hospitalisation Growth Associated With Statewide Mask Mandates

#Plasma tissue plasminogen activator and plasminogen activator inhibitor-1 in hospitalized #COVID-19 patients

Patients with coronavirus disease-19 (COVID-19) are at high risk for thrombotic arterial and venous occlusions. However, bleeding complications have also been observed in some patients. Understanding the balance between coagulation and fibrinolysis will help inform optimal approaches to thrombosis prophylaxis and potential utility of fibrinolytic-targeted therapies. 118 hospitalized COVID-19 patients and 30 healthy controls were… Continue reading #Plasma tissue plasminogen activator and plasminogen activator inhibitor-1 in hospitalized #COVID-19 patients

#COVID-19 Outcomes Among Persons Living With or Without Diagnosed #HIV Infection in New York State

New York State has been an epicenter for both the US coronavirus disease 2019 (COVID-19) and HIV/AIDS epidemics. Persons living with diagnosed HIV may be more prone to COVID-19 infection and severe outcomes, yet few studies have assessed this possibility at a population level.. ..A total of 2988 persons living with diagnosed HIV (2109 men… Continue reading #COVID-19 Outcomes Among Persons Living With or Without Diagnosed #HIV Infection in New York State

Increased #alcohol use during the #COVID-19 pandemic: The effect of mental health and age in a cross-sectional sample of social media users in the U.S.

The COVID-19 pandemic has triggered a public health crisis of unprecedented scale. Increased alcohol use has been extensively documented during other crises, particularly among persons with anxiety and depression. Despite COVID-19's differential impact by age, the association of age, mental health and alcohol use during the pandemic has not been explored. This study aimed to… Continue reading Increased #alcohol use during the #COVID-19 pandemic: The effect of mental health and age in a cross-sectional sample of social media users in the U.S.

A Little #Autonomy Support Goes a Long Way: Daily Autonomy‐Supportive Parenting, Child Well‐Being, Parental Need Fulfillment, and Change in Child, Family, and Parent Adjustment Across the Adaptation to the #COVID‐19 Pandemic

This study examined the effects of daily parental autonomy support on changes in child behavior, family environment, and parental well‐being across 3 weeks during the COVID‐19 pandemic in Germany. Day‐to‐day associations among autonomy‐supportive parenting, parental need fulfillment, and child well‐being were also assessed. Parents (longitudinal N = 469; Mage = 42.93, SDage = 6.40) of… Continue reading A Little #Autonomy Support Goes a Long Way: Daily Autonomy‐Supportive Parenting, Child Well‐Being, Parental Need Fulfillment, and Change in Child, Family, and Parent Adjustment Across the Adaptation to the #COVID‐19 Pandemic

Are Patients With Inflammatory Bowel Disease at an Increased Risk of Developing #SARS-CoV-2 than Patients Without Inflammatory #Bowel Disease? Results From a Nationwide Veterans’ Affairs Cohort Study

The clinic course of SARS-CoV-2 among patients with inflammatory bowel disease (IBD) has been extensively studied. However, there is a paucity of data on whether patients with IBD have an increased risk of developing SARS-CoV-2 with compared with patients without IBD. METHODS: We conducted a nationwide retrospective cohort study in the US Veterans’ Affairs healthcare… Continue reading Are Patients With Inflammatory Bowel Disease at an Increased Risk of Developing #SARS-CoV-2 than Patients Without Inflammatory #Bowel Disease? Results From a Nationwide Veterans’ Affairs Cohort Study

#Metformin Use Is Associated With Reduced Mortality in a Diverse Population With #COVID-19 and Diabetes

Coronavirus disease-2019 (COVID-19) is a growing pandemic with an increasing death toll that has been linked to various comorbidities as well as racial disparity. However, the specific characteristics of these at-risk populations are still not known and approaches to lower mortality are lacking.. ..The odds ratio of contracting COVID-19 was disproportionately high in Blacks/African-Americans (OR… Continue reading #Metformin Use Is Associated With Reduced Mortality in a Diverse Population With #COVID-19 and Diabetes

EUGLYCEMIC DIABETIC #KETOACIDOSIS WITH #COVID-19 INFECTION IN PATIENTS WITH TYPE 2 DIABETES TAKING #SGLT2 INHIBITORS

Diabetes mellitus is associated with poor outcomes in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Diabetic ketoacidosis (DKA) has also been reported to occur with this virus. A cluster of cases of euglycemic DKA (euDKA) was identified in patients with type 2 diabetes mellitus using sodium-glucose cotransporter-2 inhibitors (SGLT2is) who developed SARS-CoV-2 infection.. ..Five… Continue reading EUGLYCEMIC DIABETIC #KETOACIDOSIS WITH #COVID-19 INFECTION IN PATIENTS WITH TYPE 2 DIABETES TAKING #SGLT2 INHIBITORS