The long-term health consequences of COVID-19 remain largely unclear. The aim of this study was to describe the long-term health consequences of patients with COVID-19 who have been discharged from hospital and investigate the associated risk factors, in particular disease severity.. ..In total, 1733 of 2469 discharged patients with COVID-19 were enrolled after 736 were… Continue reading 6-month consequences of #COVID-19 in patients discharged from hospital: a cohort study
Tag: coronavirus
Progression of #Myopia in School-Aged Children After #COVID-19 Home Confinement
Time spent in outdoor activities has decreased owing to home confinement for the coronavirus disease 2019 (COVID-19) pandemic. Concerns have been raised about whether home confinement may have worsened the burden of myopia owing to substantially decreased time spent outdoors and increased screen time at home.. .. Of the 123 535 children included in the study,… Continue reading Progression of #Myopia in School-Aged Children After #COVID-19 Home Confinement
Evaluating the impact of a time orientation intervention on #well-being during the #COVID-19 lockdown: past, present or future?
Lockdown policies brought on by the COVID-19 pandemic pose a threat to well-being. This study examined the effectiveness of three positive psychology interventions, with different time-orientations, on well-being as well as predictors of well-being during lockdown. Participants (n= 216) completed measures of lockdown characteristics, attachment orientation, and emotion regulation, were then randomly allocated to one… Continue reading Evaluating the impact of a time orientation intervention on #well-being during the #COVID-19 lockdown: past, present or future?
Early High-Titer #Plasma Therapy to Prevent Severe #Covid-19 in Older Adults
Therapies to interrupt the progression of early coronavirus disease 2019 (Covid-19) remain elusive. Among them, convalescent plasma administered to hospitalized patients has been unsuccessful, perhaps because antibodies should be administered earlier in the course of illness. We conducted a randomized, double-blind, placebo-controlled trial of convalescent plasma with high IgG titers against severe acute respiratory syndrome… Continue reading Early High-Titer #Plasma Therapy to Prevent Severe #Covid-19 in Older Adults
Low vitamin #D status is associated with #coronavirus disease 2019 outcomes: A systematic review and meta-analysis
Observational studies suggest that the risk and clinical prognosis of coronavirus disease 2019 (COVID-19) are related to low vitamin D status; however, the data are inconsistent.. ..A total of 10 articles with 361, 934 participants were selected for meta-analysis. Overall, the pooled OR in the fixed-effect model showed that vitamin D deficiency or insufficiency was… Continue reading Low vitamin #D status is associated with #coronavirus disease 2019 outcomes: A systematic review and meta-analysis
mRNA #Covid-19 #vaccines
The Advisory Committee on Immunization Practices (ACIP) has issued interim recommendations for the use of Pfizer-BioNTech and Moderna COVID-19 vaccines for the prevention of coronavirus disease 2019 (COVID-19) in the United States. Both vaccines are lipid nanoparticle-formulated, nucleoside-modified mRNA vaccines encoding the prefusion spike glycoprotein of SARS-CoV-2, the virus that causes COVID-19. These interim CDC… Continue reading mRNA #Covid-19 #vaccines
#Baricitinib plus #Remdesivir for Hospitalized Adults with #Covid-19
Severe coronavirus disease 2019 (Covid-19) is associated with dysregulated inflammation. The effects of combination treatment with baricitinib, a Janus kinase inhibitor, plus remdesivir are not known. METHODS We conducted a double-blind, randomized, placebo-controlled trial evaluating baricitinib plus remdesivir in hospitalized adults with Covid-19. All the patients received remdesivir (≤10 days) and either baricitinib (≤14 days)… Continue reading #Baricitinib plus #Remdesivir for Hospitalized Adults with #Covid-19
Clinical Outcomes in Patients With Heart #Failure Hospitalized With #COVID-19
The purpose of this study was to evaluate in-hospital outcomes among patients with a history of heart failure (HF) hospitalized with coronavirus disease-2019 (COVID-19).. ..Among 1,212,153 patients with history of HF, 132,312 patients were hospitalized from April 1, 2020, to September 30, 2020. A total of 23,843 patients (18.0%) were hospitalized with acute HF, 8,383… Continue reading Clinical Outcomes in Patients With Heart #Failure Hospitalized With #COVID-19
A Neutralizing Monoclonal #Antibody for Hospitalized Patients with Covid-19
LY-CoV555, a neutralizing monoclonal antibody, has been associated with a decrease in viral load and the frequency of hospitalizations or emergency department visits among outpatients with coronavirus disease 2019 (Covid-19). Data are needed on the effect of this antibody in patients who are hospitalized with Covid-19 METHODS In this platform trial of therapeutic agents, we… Continue reading A Neutralizing Monoclonal #Antibody for Hospitalized Patients with Covid-19