Question Is a higher level of sodium intake associated with risk of atopic dermatitis (AD)?Findings In this cross-sectional study of 215 832 adults from the UK Biobank cohort, a 1-g higher estimated 24-hour urine sodium excretion was associated with an 11% higher odds of AD diagnosis, 16% higher odds of active AD, and 11% higher odds of increasing… Continue reading #Sodium Intake and #Atopic Dermatitis
Tag: atopy
#ATOPIC DERMATITIS PATIENT EXPERIENCE WITH DISCUSSING AND ADDRESSING MENTAL HEALTH CONCERNS WITH ALLERGISTS
Atopic dermatitis (AD) is the most common form of eczema and has a significant, multidimensional burden of disease. Patients with AD have an increased likelihood of developing depression and anxiety, which is exacerbated when additional atopic comorbidities are present. Little is known about the patient experience with discussing or addressing mental health concerns with their… Continue reading #ATOPIC DERMATITIS PATIENT EXPERIENCE WITH DISCUSSING AND ADDRESSING MENTAL HEALTH CONCERNS WITH ALLERGISTS
Risk of #Inflammatory #Bowel Disease in Patients With #Atopic Dermatitis
Data on the association between atopic dermatitis (AD) and inflammatory bowel disease (IBD) are inconsistent. Few studies have examined the association of AD or AD severity with risk of ulcerative colitis (UC) and Crohn disease (CD) separately.Objectives To examine the risk of new-onset IBD, UC, and CD in children and adults with AD. Design, Setting, and… Continue reading Risk of #Inflammatory #Bowel Disease in Patients With #Atopic Dermatitis
Increased risk of osteoarthritis in patients with atopic disease
Objectives To determine the incidence of osteoarthrits (OA) in patients with atopic disease compared with matched non-exposed patients.Methods We conducted a retrospective cohort study with propensity score matching using claims data from Optum’s de-identified Clinformatics Data Mart (CDM) (January 2003 to June 2019) and electronic health record data from the Stanford Research Repository (STARR) (January 2010 to… Continue reading Increased risk of osteoarthritis in patients with atopic disease
Guidelines of care for the management of atopic dermatitis in adults with topical therapies
BackgroundNew evidence has emerged since the 2014 guidelines that further informs the management of AD with topical therapies. These guidelines update the 2014 recommendations for management of atopic dermatitis (AD) with topical therapies.ObjectiveTo provide evidence-based recommendations related to management of AD in adults using topical treatments.MethodsA multidisciplinary workgroup conducted a systematic review and applied the… Continue reading Guidelines of care for the management of atopic dermatitis in adults with topical therapies
Prenatal antibiotic exposure, asthma and the atopic march: A systematic review and meta-analysis
BackgroundAntibiotic use during pregnancy may increase the risk for asthma in children. We performed a meta-analysis assessing prenatal antibiotic exposure and the risk for childhood wheeze or asthma, as well as for diseases associated with the atopic march. MethodsA systematic literature search protocol (PROSPERO-ID: CRD42020191940) was registered and searches were completed using Medline, Proquest, Embase,… Continue reading Prenatal antibiotic exposure, asthma and the atopic march: A systematic review and meta-analysis
Nemolizumab plus topical agents in patients with atopic dermatitis (AD) and moderate-to-severe pruritus provide improvement in pruritus and signs of AD for up to 68 weeks: results from two phase III, long-term studies
Interleukin (IL)-31 affects the inflammatory response, is involved in epidermal barrier disruption in atopic dermatitis (AD) and plays a key role in pruritus. Nemolizumab, a humanized monoclonal antibody against IL-31 receptor A, reduced pruritus in patients with AD after a 16-week administration period. ObjectivesTo examine the long-term effectiveness and safety of nemolizumab in patients aged… Continue reading Nemolizumab plus topical agents in patients with atopic dermatitis (AD) and moderate-to-severe pruritus provide improvement in pruritus and signs of AD for up to 68 weeks: results from two phase III, long-term studies
Risk factors for developing COVID-19: a population-based longitudinal study (COVIDENCE UK)
Risk factors for severe COVID-19 include older age, male sex, obesity, black or Asian ethnicity and underlying medical conditions. Whether these factors also influence susceptibility to developing COVID-19 is uncertain. Methods We undertook a prospective, population-based cohort study (COVIDENCE UK) from 1 May 2020 to 5 February 2021. Baseline information on potential risk factors was… Continue reading Risk factors for developing COVID-19: a population-based longitudinal study (COVIDENCE UK)
Association Between #Atopic Eczema and #Cancer in England and Denmark
Associations between atopic eczema and cancer are unclear, with competing theories that increased immune surveillance decreases cancer risk and that immune stimulation increases cancer risk. Establishing baseline cancer risk in people with atopic eczema is important before exploring the association between new biologic drugs for atopic eczema and cancer risk.. ..In England, matched cohorts included… Continue reading Association Between #Atopic Eczema and #Cancer in England and Denmark
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