Background: A novel approach to improve bystander defibrillation for out-of-hospital cardiac arrests is to dispatch and deliver an automated external defibrillator (AED) directly to the suspected cardiac arrest location by drone. The aim of this study was to investigate how often a drone could deliver an AED before ambulance arrival and to measure the median time… Continue reading #Drone delivery of automated external #defibrillators compared with ambulance arrival in real-life suspected out-of-hospital cardiac arrests: a prospective observational study in Sweden
Healthy Prenatal #Dietary Pattern and Offspring #Autism
Question What is the association between a healthy prenatal dietary pattern and offspring autism diagnosis and autism-associated traits in 2 large prospective cohort studies: the Norwegian Mother, Father, and Child Cohort (MoBa) and the Avon Study of Parents and Children (ALSPAC)?Findings In this cohort study including 84 548 mother-infant dyads in MoBa and 11 670 mother-infant dyads in ALSPAC,… Continue reading Healthy Prenatal #Dietary Pattern and Offspring #Autism
The association between dietary vitamin #B1 intake and #constipation: a population-based study
BackgroundNumerous researches have indicated a correlation between the intake of dietary micronutrients and the occurrence of constipation. Nevertheless, the correlation between constipation and vitamin B1 remains uninvestigated. The main aim of this research was to examine the association between chronic constipation and the consumption of vitamin B1 in the diet among adult participants of the… Continue reading The association between dietary vitamin #B1 intake and #constipation: a population-based study
#Dried fruit intake and lower risk of type 2 #diabetes: a two-sample mendelian randomization study
BackgroundPrevious studies have shown controversy about whether dried fruit intake is associated with type 2 diabetes. This study aimed to examine the potential causal effect of dried fruit intake on type 2 diabetes by conducting a two-sample Mendelian randomization study.MethodsWe used genome-wide association study (GWAS) summary statistics for MR analysis to explore the causal association… Continue reading #Dried fruit intake and lower risk of type 2 #diabetes: a two-sample mendelian randomization study
Long-Term Improvement in Hippocampal-Dependent #Learning Ability in Healthy, Aged Individuals Following High Intensity Interval #Training
AbstractPhysical exercise may reduce dementia risk in aging, but varying reports on its effectiveness make it challenging to ascribe what level of exercise will have significant longer-term effects on important functions such as hippocampal-based learning and memory. This study compared the effect of three different 6-month exercise regimens on hippocampal-dependent cognition in healthy, elderly individuals.… Continue reading Long-Term Improvement in Hippocampal-Dependent #Learning Ability in Healthy, Aged Individuals Following High Intensity Interval #Training
A case of biopsy-proven inflammatory dilated #cardiomyopathy following heterologous #mRNA -1273 third-dose immunization
Advances in mRNA vaccination against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have helped curb the coronavirus disease 2019 (COVID-19) pandemic and prevent disease onset and severity. Growing cases of vaccine-associated myocarditis (VAM) following SARS-CoV-2 immunization have been reported. Although COVID-19 VAM commonly occurs in young males after the second dose of vaccination, most cases are… Continue reading A case of biopsy-proven inflammatory dilated #cardiomyopathy following heterologous #mRNA -1273 third-dose immunization
#Screen Media Use and #Mental Health of Children and AdolescentsA Secondary Analysis of a Randomized Clinical Trial
Importance Excessive screen media use has been associated with poorer mental health among children and adolescents in several observational studies. However, experimental evidence supporting this hypothesis is lacking.Objective To investigate the effects of a 2-week screen media reduction intervention on children’s and adolescents’ mental health.Design, Setting, and Participants This prespecified secondary analysis of a cluster randomized clinical trial… Continue reading #Screen Media Use and #Mental Health of Children and AdolescentsA Secondary Analysis of a Randomized Clinical Trial
Molecular dissection of cobra #venom highlights #heparinoids as an antidote for spitting cobra envenoming
Editor’s summarySnakebite is considered a neglected tropical disease by the World Health Organization, and although antibody-based antivenoms exist, they are species specific, are expensive, and require cold storage as well as intravenous administration in a health care setting. Here, Du and colleagues conducted a whole-genome CRISPR knockout screen to identify genes required for spitting cobra… Continue reading Molecular dissection of cobra #venom highlights #heparinoids as an antidote for spitting cobra envenoming
#Diet shapes the metabolite profile in the intact human ileum, which affects PYY release
The human ileum contains a high density of enteroendocrine L-cells, which release the appetite-suppressing hormones glucagon-like peptide-1 (GLP-1) and peptide tyrosine tyrosine (PYY) in response to food intake. Recent evidence highlighted the potential role of food structures in PYY release, but the link between food structures, ileal metabolites, and appetite hormone release remains unclear owing… Continue reading #Diet shapes the metabolite profile in the intact human ileum, which affects PYY release
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