Background: Bipolar disorder is a chronic psychiatric condition characterized by alternating episodes of mania and depression, and the prediction and management of mood episodes remain significant clinical challenges. Traditional assessments of mood states have largely relied on subjective methods, such as clinical interviews and self-report questionnaires, which present limitations in terms of early detection and… Continue reading #Wearable -derived heart rate variability and sleep monitoring as predictors of #mood episodes in bipolar disorder: a case report
An Analysis of Initial Loop #Diuretic Dosing Strategies and Its Association with Time to #Decongestion
Background: There is currently a lack of evidence on the optimal loop diuretic dosing strategy in cases of acute decompensated heart failure (ADHF). Current consensus recommendations suggest starting with a dose of at least 2 times the patient’s home loop diuretic dose. Objective: This study assessed whether higher initial loop diuretic doses are associated with… Continue reading An Analysis of Initial Loop #Diuretic Dosing Strategies and Its Association with Time to #Decongestion
Effect of Sodium-Glucose Co-transporter 2 ( #SGLT2 ) Inhibitors in the Management of #Hyponatremia Associated With Syndrome of Inappropriate Antidiuresis
AbstractBackground: Hyponatremia due to syndrome of inappropriate antidiuresis (SIAD) is a common and challenging electrolyte disorder, particularly in hospitalized and elderly patients. Conventional treatments, such as fluid restriction and vasopressin receptor antagonists, have limitations related to efficacy, tolerance, availability, and cost. Sodium-glucose co-transporter 2 inhibitors (SGLT2i), primarily used for type 2 diabetes, have shown potential… Continue reading Effect of Sodium-Glucose Co-transporter 2 ( #SGLT2 ) Inhibitors in the Management of #Hyponatremia Associated With Syndrome of Inappropriate Antidiuresis
The Impact of #Probiotics on #Acne Vulgaris: A Meta-Analysis of Randomized Controlled Trials
Acne vulgaris is a multifactorial inflammatory skin disorder influenced by hormonal activity, microbial imbalance, and immune dysregulation. While conventional treatments such as antibiotics and retinoids remain effective, their long-term use is often limited by side effects, resistance, and poor adherence. This meta-analysis evaluated the efficacy of probiotics as an adjunct or alternative therapy for acne… Continue reading The Impact of #Probiotics on #Acne Vulgaris: A Meta-Analysis of Randomized Controlled Trials
Effects of #Electroacupuncture at #ST36 on Visceral Pain and Inflammatory Markers in #IBS Rats
Irritable bowel syndrome (IBS) is characterized by recurrent visceral pain associated with low-grade gut inflammation. Electroacupuncture (EA) at acupoint ST36 (Zusanli) is reputed to alleviate gastrointestinal disorders, but its effects on IBS-related visceral hypersensitivity and inflammation remain to be fully elucidated. This study evaluated whether EA at ST36 attenuates visceral pain and modulates key inflammatory… Continue reading Effects of #Electroacupuncture at #ST36 on Visceral Pain and Inflammatory Markers in #IBS Rats
Clinical outcomes of #orthopaedic surgery patients with inferior vena #cava filter prophylaxis
AbstractPurpose: Orthopaedic surgery patients are at an elevated risk of venous thromboembolic events thus necessitating effective prophylaxis strategies.Methods: This IRB-approved, single-center retrospective study evaluated patients who underwent orthopaedic surgery and were protected with Inferior Vena Cava (IVC) filters from January 2007 to December 2021. Study outcomes include incidence of venous thromboembolism (VTE) in the form… Continue reading Clinical outcomes of #orthopaedic surgery patients with inferior vena #cava filter prophylaxis
Practical #guidelines on medical management of adults with moderate-to-severe #inflammatory bowel disease
Inflammatory bowel disease (IBD) is a chronic, relapsing inflammatory disorder that predominantly includes Crohn’s disease (CD) and ulcerative colitis (UC). IBD has emerged as a significant healthcare challenge in Saudi Arabia, with a more than fivefold increase in annual incidence over the past 2 decades. These guidelines promote high-quality, evidence-based care for adult patients with… Continue reading Practical #guidelines on medical management of adults with moderate-to-severe #inflammatory bowel disease
The Overlooked Driver of #Hypertension: Mental #Stress at the Crossroad of Cardiology and Psychiatry
AbstractPurpose of ReviewMental stress has long been overlooked in the development of hypertension. We aim to provide new insights for clinicians in managing this condition.This review aims to summarize the epidemiological characteristics, complex mechanisms, diagnostic methods, as well as both non-pharmacological and pharmacological treatment strategies for mental stress-induced hypertension.Recent FindingsMany hypertensive patients continue to experience… Continue reading The Overlooked Driver of #Hypertension: Mental #Stress at the Crossroad of Cardiology and Psychiatry
Dual target, dual benefit: real-world effects of #SGLT2 inhibitors and #GLP-1 receptor agonists on the FIB-4 score in people with type 2 #diabetes mellitus
Liver fibrosis is a serious comorbidity of type 2 diabetes mellitus (T2DM) in which non-invasive indices such as FIB-4 are used to monitor hepatic health. This study assesses the impact of GLP-1 receptor agonists (GLP-1RA), SGLT2 inhibitors (SGLT2i), and their combinations on FIB-4 scores in people with T2DM.MethodsWe conducted a retrospective analysis of 133 adults… Continue reading Dual target, dual benefit: real-world effects of #SGLT2 inhibitors and #GLP-1 receptor agonists on the FIB-4 score in people with type 2 #diabetes mellitus
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