Mid-Term Effects of Pulmonary #Rehabilitation on Cognitive Function in People with Severe Chronic Obstructive #Pulmonary Disease

Cognitive dysfunction is a common impairment associated with COPD. However, little is known about 1) its prevalence among those subjects referred for pulmonary rehabilitation (PR), 2) how it may affect the benefit of PR, 3) whether PR improves cognitive function and 4) whether cognitive dysfunction affects the usability of telehealth technology usually used to deliver… Continue reading Mid-Term Effects of Pulmonary #Rehabilitation on Cognitive Function in People with Severe Chronic Obstructive #Pulmonary Disease

Long-term dietary #flavonoid intake and risk of #Alzheimer disease and related dementias in the Framingham Offspring Cohort

Findings from existing prospective observational studies on the protective associations of flavonoid intake and the risk of Alzheimer disease and related dementias (ADRD) are inconsistent largely due to limitations of these studies.. ..Over an average follow-up of 19.7 y in 2801 participants (mean baseline age = 59.1 y; 52% females), there were 193 ADRD events… Continue reading Long-term dietary #flavonoid intake and risk of #Alzheimer disease and related dementias in the Framingham Offspring Cohort

Rebaudioside affords hepatoprotection ameliorating sugar sweetened beverage- induced nonalcoholic #steatohepatitis

Sugar-sweetened beverage consumption is a known independent risk factor for nonalcoholic steatohepatitis (NASH). Non-caloric sweeteners (NCS) are food additives providing sweetness without calories and are considered safe and/or not metabolized by the liver. The potential role of newer NCS in the regulation of NASH, however, remain unknown. Our study aimed to determine the impact of… Continue reading Rebaudioside affords hepatoprotection ameliorating sugar sweetened beverage- induced nonalcoholic #steatohepatitis

Association of Blood Pressure Lowering With Incident #Dementia or Cognitive Impairment A Systematic Review and Meta-analysis

..The mean (SD) age of trial participants was 69 (5.4) years and 40 617 (42.2%) were women. The mean systolic baseline blood pressure was 154 (14.9) mm Hg and the mean diastolic blood pressure was 83.3 (9.9) mm Hg. The mean duration of follow-up was 49.2 months. Blood pressure lowering with antihypertensive agents compared with… Continue reading Association of Blood Pressure Lowering With Incident #Dementia or Cognitive Impairment A Systematic Review and Meta-analysis

Fine Particulate Matter Air #Pollution and Mortality among Pediatric, Adolescent, and Young Adult Cancer Patients

Air pollution is a carcinogen and causes pulmonary and cardiac complications. We examined the association of fine particulate matter pollution (PM2.5) and mortality from cancer and all causes among pediatric, adolescent, and young adult (AYA) patients with cancer in Utah, a state with considerable variation in PM2.5.. ..Increases in PM2.5 per 5 μg/m3 were associated… Continue reading Fine Particulate Matter Air #Pollution and Mortality among Pediatric, Adolescent, and Young Adult Cancer Patients

ACUTE #KIDNEY INJURY IN PATIENTS HOSPITALIZED WITH #COVID-19

The rate of acute kidney injury (AKI) associated with patients hospitalized with Covid-19, and associated outcomes are not well understood. This study describes the presentation, risk factors and outcomes of AKI in patients hospitalized with Covid-19. We reviewed the health records for all patients hospitalized with Covid-19 between March 1, and April 5, 2020, at… Continue reading ACUTE #KIDNEY INJURY IN PATIENTS HOSPITALIZED WITH #COVID-19

Comparison between clinical and ultrasound assessment of the ankle region in juvenile idiopathic #arthritis

To compare frequency of joint and tendon disease on ultrasound (US) and clinical examination (CE), and to investigate agreement between US and CE in ankles with clinically active juvenile idiopathic arthritis (JIA).. ..A total of 163 joints in 89 ankles had active synovitis on US. The tibiotalar joint (TTJ) was the most commonly affected joint… Continue reading Comparison between clinical and ultrasound assessment of the ankle region in juvenile idiopathic #arthritis

Associations of #sleep duration with patient-reported outcomes and healthcare use in U.S. adults with #asthma

..Asthma was identified by self-report. Habitual hours of sleep duration were categorized as short (≤5), normal (6-8), and long (≥9). Multivariate regression analyses were used to examine the associations between sleep duration and patient-reported outcomes and healthcare use. Results Of the 1389 adults with asthma, 26% reported short sleep duration, 66% reported normal sleep duration,… Continue reading Associations of #sleep duration with patient-reported outcomes and healthcare use in U.S. adults with #asthma

Blood #Pressure at 6 Months after Acute Myocardial #Infarction and Outcomes at 2 Years: The Perils Associated With Excessively Low Blood Pressures

This study aimed to determine the association between achieved blood pressure at 6-month follow-up and cardiovascular outcomes at 2 years in patients treated with β-blockers and renin-angiotensin-aldosterone blockers after acute myocardial infarction (AMI).. ..Achieved blood pressures were categorized into 10-mm Hg increments. The primary outcome was all-cause death. The secondary outcome was a composite of… Continue reading Blood #Pressure at 6 Months after Acute Myocardial #Infarction and Outcomes at 2 Years: The Perils Associated With Excessively Low Blood Pressures