#Echoes in the night: How #sleep quality influences #auditory health

Sleep disorders may lead to hearing loss.• Complex relationship between sleep quality, auditory sense and mental health.• Oxidative stress and immune response may be potential mechanisms.• Current treatment strategies are limited and separate. AbstractThe intricate relationship between sleep disorders and hearing loss emerges as a burgeoning field of scholarly inquiry. Numerous studies have illuminated a… Continue reading #Echoes in the night: How #sleep quality influences #auditory health

A systematic review and Bayesian network meta-analysis on the efficacy and potential of #mobile interventions for #stress management

The increasing prevalence of stress underscores the demand for effective, self-administered mobile mental health interventions, yet their efficacy and accessibility are still unclear. Here, this systematic review and meta-analysis aimed to classify self-administered mobile stress management interventions, compare their efficacy and examine their moderators. We searched PsycINFO, PubMed, Web of Science, MEDLINE, Embase, CINAHL, Scopus… Continue reading A systematic review and Bayesian network meta-analysis on the efficacy and potential of #mobile interventions for #stress management

Dietary #Sugar Intake and Incident Type 2 #Diabetes Risk: A Systematic Review and Dose-Response Meta-Analysis of Prospective Cohort Studies

The dose-response relationship between dietary sugar and type 2 diabetes (T2D) risk is uncertain. MEDLINE, Embase, CINAHL, Web of Science and Cochrane databases were searched through July 9, 2024 for prospective cohort studies reporting relative measures of incident T2D risk by categories of dietary sugar (total, free, added, fructose, sucrose) or 2 beverage sources (non-diet… Continue reading Dietary #Sugar Intake and Incident Type 2 #Diabetes Risk: A Systematic Review and Dose-Response Meta-Analysis of Prospective Cohort Studies

Low-Calorie, High-Protein Ketogenic #Diet Versus Low-Calorie, Low-Sodium, and High-Potassium Mediterranean Diet in Overweight Patients and Patients with #Obesity with High-Normal Blood Pressure or Grade I #Hypertension: The Keto–Salt Pilot Study

Background and Objective: Dietary interventions are the first-line treatment for overweight individuals (OW) and individuals with obesity (OB) with high-normal blood pressure (BP) or grade I hypertension, especially when at low-to-moderate cardiovascular risk (CVR). However, current guidelines do not specify the most effective dietary approach for optimising cardiovascular and metabolic outcomes in this population. This… Continue reading Low-Calorie, High-Protein Ketogenic #Diet Versus Low-Calorie, Low-Sodium, and High-Potassium Mediterranean Diet in Overweight Patients and Patients with #Obesity with High-Normal Blood Pressure or Grade I #Hypertension: The Keto–Salt Pilot Study

Age-adjusted non-COVID-19 #mortality rates according to the #COVID-19 vaccination status

Excess mortality has been observed in several countries since 2021 and has not yet been explained. The aim of this study was to determine whether the age-adjusted mortality rates of non-COVID-19 deaths differed between those who had received one, two, three or four doses compared with the unvaccinated. Data were obtained from the Office for… Continue reading Age-adjusted non-COVID-19 #mortality rates according to the #COVID-19 vaccination status

The overlooked trio: #sleep duration, sampling time and #physical exercise alter levels of olink-assessed blood biomarkers of cardiovascular risk

Biomarker profiling from biofluids such as blood are widely measured in clinical research, using for example Olink proteomics panels. One such research focus area is cardiovascular disease (CVD), for which chronic sleep restriction (SR) is a risk factor. However, it remains unclear whether blood levels of commonly measured CVD biomarkers are sensitive to acute dynamic… Continue reading The overlooked trio: #sleep duration, sampling time and #physical exercise alter levels of olink-assessed blood biomarkers of cardiovascular risk

#Colchicine in acute #coronary syndromes: a systematic review and meta-analysis of randomised controlled trials

Background Acute coronary syndrome (ACS) is a global leading cause of morbidity, with residual inflammation contributing to recurrent events. Colchicine has been proposed as an adjunct therapy, but its efficacy remains uncertain.Methods We performed a systematic review and meta-analysis. PubMed, Embase and Cochrane databases were searched for randomised controlled trials (RCTs) data comparing colchicine versus… Continue reading #Colchicine in acute #coronary syndromes: a systematic review and meta-analysis of randomised controlled trials

Rest #Activity Rhythms and their Association with #Cardiorespiratory Fitness and #Walking Energetics in #Older Adults: Study of Muscle, #Mobility and #Aging

Purpose It is recognized that disruptions in circadian behavior, such as with shift work or jet lag, are associated with diminished health. This known relationship implies that people with stronger indices of circadian behavior will exhibit improved physiology. To address the association between rhythmic activity behavior and physiology we proposed that metrics indicative of ‘more… Continue reading Rest #Activity Rhythms and their Association with #Cardiorespiratory Fitness and #Walking Energetics in #Older Adults: Study of Muscle, #Mobility and #Aging

Vitamin #D3 and marine ω-3 fatty acids supplementation and leukocyte #telomere length: 4-year findings from the VITamin D and OmegA-3 TriaL (VITAL) randomized controlled trial

Limited studies suggest that vitamin D or omega 3 fatty acids (n–3 FAs) supplementation may be beneficial for telomere maintenance; however, evidence from large randomized clinical trials is lacking. We hypothesized that vitamin D or n–3 FAs supplementation reduce leukocyte telomere length (LTL) attrition over time by leveraging the VITamin D and OmegA-3 TriaL (VITAL)… Continue reading Vitamin #D3 and marine ω-3 fatty acids supplementation and leukocyte #telomere length: 4-year findings from the VITamin D and OmegA-3 TriaL (VITAL) randomized controlled trial