Late-life exposure to ambient air pollution is a modifiable risk factor for dementia, but epidemiological studies have shown inconsistent evidence for cognitive decline. Air quality (AQ) improvement has been associated with improved cardiopulmonary health and decreased mortality, but to the best of our knowledge, no studies have examined the association with cognitive function. We examined… Continue reading Air quality improvement and cognitive decline in community-dwelling older women in the United States: A longitudinal cohort study
Adipogenic Activity of Chemicals Used in Plastic Consumer Products
Bisphenols and phthalates, chemicals frequently used in plastic products, promote obesity in cell and animal models. However, these well-known metabolism-disrupting chemicals (MDCs) represent only a minute fraction of all compounds found in plastics. To gain a comprehensive understanding of plastics as a source of exposure to MDCs, we characterized the chemicals present in 34 everyday… Continue reading Adipogenic Activity of Chemicals Used in Plastic Consumer Products
A LITERATURE REVIEW AND META-ANALYSISOF THE EFFECTS OF LOCKDOWNS ONCOVID-19 MORTALITY
This systematic review and meta-analysis are designed to determine whether there is empiricalevidence to support the belief that “lockdowns” reduce COVID-19 mortality. Lockdowns aredefined as the imposition of at least one compulsory, non-pharmaceutical intervention (NPI).NPIs are any government mandate that directly restrict peoples’ possibilities, such as policies thatlimit internal movement, close schools and businesses, and… Continue reading A LITERATURE REVIEW AND META-ANALYSISOF THE EFFECTS OF LOCKDOWNS ONCOVID-19 MORTALITY
Myocarditis Cases Reported After mRNA-Based COVID-19 Vaccination in the US From December 2020 to August 2021
Importance Vaccination against COVID-19 provides clear public health benefits, but vaccination also carries potential risks. The risks and outcomes of myocarditis after COVID-19 vaccination are unclear. Objective to describe reports of myocarditis and the reporting rates after mRNA-based COVID-19 vaccination in the US. Design, Setting, and Participants Descriptive study of reports of myocarditis to the… Continue reading Myocarditis Cases Reported After mRNA-Based COVID-19 Vaccination in the US From December 2020 to August 2021
Perceived Physical Fatigability Predicts All-Cause Mortality in Older Adults
BackgroundPerceived physical fatigability is highly prevalent in older adults and associated with mobility decline and other health consequences. We examined the prognostic value of perceived physical fatigability as an independent predictor of risk of death among older adults. MethodsParticipants (N = 2 906), mean age 73.5 [SD, 10.4] years, 54.2% women, 99.7% white enrolled in… Continue reading Perceived Physical Fatigability Predicts All-Cause Mortality in Older Adults
Be Alert to the Risk of Adverse Cardiovascular Events after COVID-19 Vaccination
AbstractWith the global popularization of vaccination against coronavirus disease 2019 (COVID-19), the reports of cases of vaccine-related adverse events are increasing gradually. The most common events are local pain at the injection site and atypical symptoms, such as fever, headache, myalgia, and general discomfort. However, a few people might develop serious cardiovascular complications, such as… Continue reading Be Alert to the Risk of Adverse Cardiovascular Events after COVID-19 Vaccination
Neuroticism, Worry, and Cardiometabolic Risk Trajectories: Findings From a 40‐Year Study of Men
Anxiety is linked to elevated risk of cardiometabolic disease onset, but the underlying mechanisms remain unclear. We examined the prospective association of 2 anxiety facets, neuroticism and worry, with cardiometabolic risk (CMR) trajectories for 4 decades. Methods and ResultsThe sample comprised 1561 men from an ongoing adult male cohort. In 1975, healthy men (mean age,… Continue reading Neuroticism, Worry, and Cardiometabolic Risk Trajectories: Findings From a 40‐Year Study of Men
Rapid emergence of SARS-CoV-2 Omicron variant is associated with an infection advantage over Delta in vaccinated persons
The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants continues to shape the coronavirus disease 2019 (Covid-19) pandemic. The detection and rapid spread of the SARS-CoV-2 Omicron variant (lineage B.1.1.529) in Botswana and South Africa became a global concern because it contained 15 mutations in the spike protein immunogenic receptor binding domain and… Continue reading Rapid emergence of SARS-CoV-2 Omicron variant is associated with an infection advantage over Delta in vaccinated persons
The Lancet: COVID-19 pandemic led to stark rise in depressive and anxiety disorders globally in 2020, with women and younger people most affected
First global estimates of impact of the COVID-19 pandemic on mental health in 2020 suggests additional 53 million cases of major depressive disorder and 76 million cases of anxiety disorders were due to the pandemic.Women and younger people were the most affected by major depressive disorder and anxiety disorders in 2020.Countries hit hardest by the… Continue reading The Lancet: COVID-19 pandemic led to stark rise in depressive and anxiety disorders globally in 2020, with women and younger people most affected