Vaccines currently are the primary mitigation strategy to combat COVID-19 around the world. For instance, the narrative related to the ongoing surge of new cases in the United States (US) is argued to be driven by areas with low vaccination rates [1]. A similar narrative also has been observed in countries, such as Germany and… Continue reading Increases in COVID-19 are unrelated to levels of vaccination across 68 countries and 2947 counties in the United States
Loss of functional heterogeneity along the CA3 transverse axis in aging
Age-related deficits in pattern separation have been postulated to bias the output of hippocampal memory processing toward pattern completion, which can cause deficits in accurate memory retrieval. Although the CA3 region of the hippocampus is often conceptualized as a homogeneous network involved in pattern completion, growing evidence demonstrates a functional gradient in CA3 along the… Continue reading Loss of functional heterogeneity along the CA3 transverse axis in aging
Foreign Materials in Blood Samples of Recipients of COVID-19 Vaccines
The Korea Veritas Doctors (KoVeDocs) for COVID-19 previously found certain foreign materials and moving parasite-like entities in the Pfizer and Moderna mRNA COVID-19 vaccines as those vaccines were warmed to near room temperature (Jeon, 2022). Here we report on similar foreign materials found in samples of centrifuged blood from 8 COVID-19 vaccine recipients as contrasted… Continue reading Foreign Materials in Blood Samples of Recipients of COVID-19 Vaccines
All Cause Mortality and COVID-19 Injections: Evidence from 28 Weeks of Public Health England “COVID-19 Vaccine Surveillance Reports”
According to data collected in the UK for weeks 34-52 in 2021 (excluding week 51 which was not covered) and in weeks 1-12 of 2022 — a period of 28 weeks during which the genetic “vaccines” from Pfizer, Moderna, and AstraZeneca were being pressed upon the public — deaths reported to Public Health England (PHE)… Continue reading All Cause Mortality and COVID-19 Injections: Evidence from 28 Weeks of Public Health England “COVID-19 Vaccine Surveillance Reports”
Anti-HBc levels are associated with liver inflammation and response to peginterferon in chronic hepatitis B patients
BackgroundEmerging evidence suggests a pivotal role for B-cell responses in the natural history of chronic hepatitis B (CHB). Serum levels of antibodies to HBcAg (anti-HBc) vary across infection stages, but their role in predicting response to antiviral therapy is uncertain. MethodsAnti-HBc levels were assessed before peginterferon (PEG-IFN) therapy in CHB patients who either initiated de… Continue reading Anti-HBc levels are associated with liver inflammation and response to peginterferon in chronic hepatitis B patients
Revisiting Pediatric COVID-19 Cases in Counties With and Without School Mask Requirements—United States, July 1—October 20 2021
Background: There has been considerable debate around mask requirements in schools in the United States and other countries during the Covid-19 pandemic. To date, there have been no randomized controlled trials of mask requirements in children. All analyses of the effectiveness of school mask mandates have relied on observational studies. The Centers for Disease Control… Continue reading Revisiting Pediatric COVID-19 Cases in Counties With and Without School Mask Requirements—United States, July 1—October 20 2021
Effect of active vitamin D treatment on development of type 2 diabetes: DPVD randomised controlled trial in Japanese population
To assess whether eldecalcitol, an active vitamin D analogue2, can reduce the development of type 2 diabetes among adults with impaired glucose tolerance. Design Double blinded, multicentre, randomised, placebo controlled trial. Setting Three hospitals in Japan, between June 2013 and August 2019. Participants People aged 30 years and older who had impaired glucose tolerance defined… Continue reading Effect of active vitamin D treatment on development of type 2 diabetes: DPVD randomised controlled trial in Japanese population
Steroid-induced fibroblast growth factors drive an epithelial-mesenchymal inflammatory axis in severe asthma
AbstractAsthma and inflammatory airway diseases restrict airflow in the lung, compromising gas exchange and lung function. Inhaled corticosteroids (ICSs) can reduce inflammation, control symptoms, and improve lung function; however, a growing number of patients with severe asthma do not benefit from ICS. Using bronchial airway epithelial brushings from patients with severe asthma or primary human… Continue reading Steroid-induced fibroblast growth factors drive an epithelial-mesenchymal inflammatory axis in severe asthma
The unintended consequences of COVID-19 vaccine policy: why mandates, passports and restrictions may cause more harm than good
AbstractVaccination policies have shifted dramatically during COVID-19 with the rapid emergence of population-wide vaccine mandates, domestic vaccine passports and differential restrictions based on vaccination status. While these policies have prompted ethical, scientific, practical, legal and political debate, there has been limited evaluation of their potential unintended consequences. Here, we outline a comprehensive set of hypotheses… Continue reading The unintended consequences of COVID-19 vaccine policy: why mandates, passports and restrictions may cause more harm than good