Stress alters brain function by modifying the structure and function of neurons and astrocytes. The fine processes of astrocytes are critical for the clearance of neurotransmitters during synaptic transmission. Thus, experience-dependent remodeling of glial processes is anticipated to alter the output of neural circuits.. ..Significance statement Astrocytes play important roles in synaptic transmission by extending… Continue reading Emotional #stress induces structural #plasticity in Bergmann glial cells via an AC5-CPEB3-GluA1 pathway
Category: Psychiatry
Prenatal and perinatal risk and protective factors for #psychosis: a systematic review and meta-analysis
.. 152 studies relating to 98 risk or protective factors were eligible for analysis. Significant risk factors were: maternal age younger than 20 years (OR 1·17) and 30–34 years (OR 1·05); paternal age younger than 20 years (OR 1·31) and older than 35 years (OR 1·28); any maternal (OR 4·60) or paternal (OR 2·73) psychopathology;… Continue reading Prenatal and perinatal risk and protective factors for #psychosis: a systematic review and meta-analysis
Association Between Lifetime Affective Symptoms and Premature Mortality
Associations between affective problems (anxiety and depression) and premature mortality have been demonstrated among psychiatric, medical, and community-based samples and across many causes of death.. ..Of 3001 study members (1509 [50.3%] female, 1492 [49.7%] male), 235 individuals (7.8%) died over a 15-year follow-up. After adjustment for sex, those who experienced case-level affective symptoms 1, 2,… Continue reading Association Between Lifetime Affective Symptoms and Premature Mortality
Thinking ahead and staying in the present: Implications for reactivity to daily stressors
We examined how proactive coping and daily mindfulness may work together to predict emotional reactivity to daily stressors. Using data from the Mindfulness and Anticipatory Coping Everyday study (MACE; Neupert & Bellingtier, 2017; Neupert & Bellingtier, 2019), 116 older adults and 107 younger adults participated in a daily diary study for nine consecutive days. Results… Continue reading Thinking ahead and staying in the present: Implications for reactivity to daily stressors
Factors Associated With #Mental Health Outcomes Among Health Care Workers Exposed to #Coronavirus Disease 2019
.. A total of 1257 of 1830 contacted individuals completed the survey, with a participation rate of 68.7%. A total of 813 (64.7%) were aged 26 to 40 years, and 964 (76.7%) were women. Of all participants, 764 (60.8%) were nurses, and 493 (39.2%) were physicians; 760 (60.5%) worked in hospitals in Wuhan, and 522… Continue reading Factors Associated With #Mental Health Outcomes Among Health Care Workers Exposed to #Coronavirus Disease 2019
#Alcohol Use Disorder and Risk of #Suicide in a Swedish Population-Based Cohort
..The lifetime rate of suicide during the observation period was 3.54% for women and 3.94% for men with AUD, compared with 0.29% and 0.76% of women and men, respectively, without AUD. In adjusted analyses, AUD remained robustly associated with suicide: hazard ratios across observation periods ranged from 2.61 to 128.0 among women and from 2.44… Continue reading #Alcohol Use Disorder and Risk of #Suicide in a Swedish Population-Based Cohort
Decreasing #Delirium Through #Music: A Randomized Pilot Trial
To determine the feasibility and acceptability of personalized music (PM), slow-tempo music (STM), and attention control (AC) in patients receiving mechanical ventilation in an intensive care unit, and to estimate the effect of music on delirium.. ..Of the 1589 patients screened, 117 (7.4%) were eligible. Of those, 52 (44.4%) were randomized, with a recruitment rate… Continue reading Decreasing #Delirium Through #Music: A Randomized Pilot Trial
#Alcoholics Anonymous and other 12‐step programs for #alcohol use disorder
Alcohol use disorder (AUD) confers a prodigious burden of disease, disability, premature mortality, and high economic costs from lost productivity, accidents, violence, incarceration, and increased healthcare utilization. For over 80 years, Alcoholics Anonymous (AA) has been a widespread AUD recovery organization, with millions of members and treatment free at the point of access, but it… Continue reading #Alcoholics Anonymous and other 12‐step programs for #alcohol use disorder
Early- Versus Adult-Onset #Schizophrenia as a Predictor of Response to Neuroscience-Informed Cognitive Training
Developmental stages characterized by greater neural plasticity might be critical periods during which the effects of cognitive training (CT) could theoretically be maximized. However, experiencing a first episode of schizophrenia during childhood or adolescence (ie, early-onset schizophrenia [EOS]) may reduce the brain’s ability to benefit from CT. This study examined the effects of EOS versus… Continue reading Early- Versus Adult-Onset #Schizophrenia as a Predictor of Response to Neuroscience-Informed Cognitive Training
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