The long-term prognosis after cognitive behavioral therapy (CBT) in outpatient groups for panic disorder and agoraphobia is not well known. The purpose of this study was to assess long-term outcomes in terms of psychological health, health-related quality of life (HRQoL), quality of life (QoL) and treatment satisfaction after CBT for panic disorder and agoraphobia ..The… Continue reading #Cognitive behavioral group therapy for panic disorder in a general clinical setting: a prospective cohort study with 12 to 31-years follow-up
Category: Psychiatry
Assessment of a Prediction Model for Antidepressant Treatment Stability Using Supervised Topic Models
..Stable treatment response, intended as a proxy for treatment effectiveness, defined as continued prescription of an antidepressant for 90 days. Supervised topic models were used to extract 10 interpretable covariates from coded clinical data for stability prediction. With use of data from 1 hospital system (site A), generalized linear models and ensembles of decision trees… Continue reading Assessment of a Prediction Model for Antidepressant Treatment Stability Using Supervised Topic Models
Effects of #yoga on depressive symptoms in people with mental disorders: a systematic review and meta-analysis
..Eligibility criteria for selecting studies We included randomised controlled trials with a yoga intervention comprising ≥50% physical activity in adults with a recognised diagnosed mental disorder according to DSM-3, 4 or 5. Results 19 studies were included in the review (1080 participants) and 13 studies were included in the meta-analysis (632 participants). Disorders of depression,… Continue reading Effects of #yoga on depressive symptoms in people with mental disorders: a systematic review and meta-analysis
Association of Childhood #Psychosocial Environment With 30‐Year #Cardiovascular Disease Incidence and Mortality in Middle Age
Childhood adversity and trauma have been shown to be associated with poorer cardiovascular disease (CVD) outcomes in adulthood. However, longitudinal studies of this association are rare.. ..Participants (n=3646) completed the Childhood Family Environment (CFE) questionnaire at the year 15 (2000–2001) CARDIA examination and were grouped by high, moderate, or low relative CFE adversity scores.. ..Participants… Continue reading Association of Childhood #Psychosocial Environment With 30‐Year #Cardiovascular Disease Incidence and Mortality in Middle Age
Association between #Mental Disorders and Subsequent Medical Conditions
..A total of 698,874 of 5,940,299 persons (11.8%) were identified as having a mental disorder. The median age of the total population was 32.1 years at entry into the cohort and 48.7 years at the time of the last follow-up. Persons with a mental disorder had a higher risk than those without such disorders with… Continue reading Association between #Mental Disorders and Subsequent Medical Conditions
#Circadian rhythm and sleep alterations in older people with lifetime #depression: a case-control study
Depression is common in older people and is associated with underlying brain change increasing the risk of dementia. Sleep disturbance is frequently reported by those with lifetime depression, however whether circadian misalignment also exists is unclear. We aimed to examine circadian rhythms and sleep associations in older patients with and without lifetime depression.. ..Participants underwent… Continue reading #Circadian rhythm and sleep alterations in older people with lifetime #depression: a case-control study
High incidence of #hepatocellular carcinoma and #cirrhotic complications in patients with psychiatric illness: a territory-wide cohort study
Because of high-risk behaviours, sedentary lifestyle and side effects of medications, psychiatric patients are at risk of viral hepatitis, alcohol-related liver disease and non-alcoholic fatty liver disease. We aimed to study the incidence of hepatocellular carcinoma (HCC) and cirrhotic complications in psychiatric patients.. ..We included 105,763 psychiatric patients without prior liver-related events in the final… Continue reading High incidence of #hepatocellular carcinoma and #cirrhotic complications in patients with psychiatric illness: a territory-wide cohort study
Inflammatory modulation of #fluoxetine use in patients with #depression: A systematic review and meta-analysis
There is growing evidence that there is a relationship between major depressive disorder (MDD), also simply known as “depression”, and inflammatory processes. Selective serotonin inhibitors, such as fluoxetine, are used as a first-line treatment for depression, and it is hypothesized that its use can reduce levels of proinflammatory cytokines. The aim of this systematic review… Continue reading Inflammatory modulation of #fluoxetine use in patients with #depression: A systematic review and meta-analysis
Emotional #Stress Induces Structural Plasticity in Bergmann Glial Cells via an AC5–CPEB3–GluA1 Pathway
..SIGNIFICANCE STATEMENT Astrocytes play important roles in synaptic transmission by extending fine processes around synapses. In this study, we showed that a single exposure to an acute stress triggered a retraction of lateral/fine processes in mouse cerebellar astrocytes. These astrocytes express GluA1, a glutamate receptor subunit known to lengthen astrocyte processes. We showed that astrocytic… Continue reading Emotional #Stress Induces Structural Plasticity in Bergmann Glial Cells via an AC5–CPEB3–GluA1 Pathway
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