Childhood adversity and trauma have been shown to be associated with poorer cardiovascular disease (CVD) outcomes in adulthood. However, longitudinal studies of this association are rare.. ..Participants (n=3646) completed the Childhood Family Environment (CFE) questionnaire at the year 15 (2000–2001) CARDIA examination and were grouped by high, moderate, or low relative CFE adversity scores.. ..Participants… Continue reading Association of Childhood #Psychosocial Environment With 30‐Year #Cardiovascular Disease Incidence and Mortality in Middle Age
Category: Psychiatry
Association between #Mental Disorders and Subsequent Medical Conditions
..A total of 698,874 of 5,940,299 persons (11.8%) were identified as having a mental disorder. The median age of the total population was 32.1 years at entry into the cohort and 48.7 years at the time of the last follow-up. Persons with a mental disorder had a higher risk than those without such disorders with… Continue reading Association between #Mental Disorders and Subsequent Medical Conditions
#Circadian rhythm and sleep alterations in older people with lifetime #depression: a case-control study
Depression is common in older people and is associated with underlying brain change increasing the risk of dementia. Sleep disturbance is frequently reported by those with lifetime depression, however whether circadian misalignment also exists is unclear. We aimed to examine circadian rhythms and sleep associations in older patients with and without lifetime depression.. ..Participants underwent… Continue reading #Circadian rhythm and sleep alterations in older people with lifetime #depression: a case-control study
High incidence of #hepatocellular carcinoma and #cirrhotic complications in patients with psychiatric illness: a territory-wide cohort study
Because of high-risk behaviours, sedentary lifestyle and side effects of medications, psychiatric patients are at risk of viral hepatitis, alcohol-related liver disease and non-alcoholic fatty liver disease. We aimed to study the incidence of hepatocellular carcinoma (HCC) and cirrhotic complications in psychiatric patients.. ..We included 105,763 psychiatric patients without prior liver-related events in the final… Continue reading High incidence of #hepatocellular carcinoma and #cirrhotic complications in patients with psychiatric illness: a territory-wide cohort study
Inflammatory modulation of #fluoxetine use in patients with #depression: A systematic review and meta-analysis
There is growing evidence that there is a relationship between major depressive disorder (MDD), also simply known as “depression”, and inflammatory processes. Selective serotonin inhibitors, such as fluoxetine, are used as a first-line treatment for depression, and it is hypothesized that its use can reduce levels of proinflammatory cytokines. The aim of this systematic review… Continue reading Inflammatory modulation of #fluoxetine use in patients with #depression: A systematic review and meta-analysis
Emotional #Stress Induces Structural Plasticity in Bergmann Glial Cells via an AC5–CPEB3–GluA1 Pathway
..SIGNIFICANCE STATEMENT Astrocytes play important roles in synaptic transmission by extending fine processes around synapses. In this study, we showed that a single exposure to an acute stress triggered a retraction of lateral/fine processes in mouse cerebellar astrocytes. These astrocytes express GluA1, a glutamate receptor subunit known to lengthen astrocyte processes. We showed that astrocytic… Continue reading Emotional #Stress Induces Structural Plasticity in Bergmann Glial Cells via an AC5–CPEB3–GluA1 Pathway
#Mood Homeostasis, Low Mood, and History of #Depression in 2 Large Population Samples
..To assess whether mood homeostasis (ie, the stabilization of one’s mood by engaging in mood-modifying activities) is a possible new therapeutic target by testing the hypothesis that people with low (vs high) mean mood and people with (vs without) a history of depression have impaired mood homeostasis.. ..A total of 28 212 participants from the 58sec… Continue reading #Mood Homeostasis, Low Mood, and History of #Depression in 2 Large Population Samples
#Coronavirus: Lockdown’s heavy toll on Italy’s mental health
Italy’s coronavirus death toll is the second highest in the world, and its lockdown is the strictest and longest in Europe. Doctors say both things are creating a mental health emergency. The BBC has been given access to a psychological support centre run by the Red Cross, where staff say they’re overwhelmed by calls from… Continue reading #Coronavirus: Lockdown’s heavy toll on Italy’s mental health
Adherence to Life-Style Recommendations and #Attention-Deficit/Hyperactivity Disorder A Population-Based Study of Children Aged 10 to 11 Years
The incidence of attention-deficit/hyperactivity disorder (ADHD) among children and youth is high, and temporal increases have been paralleled by deteriorating life-styles. Poor diet quality, physical inactivity, poor sleep habits, and sedentary behaviors have all been associated with ADHD.. ..Before age 14 years, 10.8% of students received an ADHD diagnosis. Meeting recommendations for vegetables and fruit,… Continue reading Adherence to Life-Style Recommendations and #Attention-Deficit/Hyperactivity Disorder A Population-Based Study of Children Aged 10 to 11 Years
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