..For ischaemic stroke (4281 cases), lower risks were observed with higher consumption of fruit and vegetables combined (HR; 95% CI per 200 g/day higher intake, 0.87; 0.82–0.93, P-trend < 0.001), dietary fibre (per 10 g/day, 0.77; 0.69–0.86, P-trend < 0.001), milk (per 200 g/day, 0.95; 0.91–0.99, P-trend = 0.02), yogurt (per 100 g/day, 0.91; 0.85–0.97, P-trend = 0.004), and cheese (per 30 g/day, 0.88; 0.81–0.97, P-trend = 0.008), while higher… Continue reading The associations of major #foods and fibre with risks of ischaemic and haemorrhagic #stroke: a prospective study of 418 329 participants in the EPIC cohort across nine European countries
Category: Neurology
Association of Dual Decline in Memory and #Gait Speed With Risk for #Dementia Among Adults Older Than 60 Years
Dual decline in both memory and gait speed may characterize a group of older individuals at high risk for future dementia.. ..Participants were 60 years or older, had an initial gait speed of more than 0.6 m/s (ie, free of overt dismobility), with repeated measures of memory and gait speed before dementia diagnosis during a… Continue reading Association of Dual Decline in Memory and #Gait Speed With Risk for #Dementia Among Adults Older Than 60 Years
The association between actor/partner #optimism and #cognitive functioning among older couples
Higher optimism has been linked with health, well‐being, and cognitive functioning. Spouses also play an important role on people's health, especially in older adulthood.. ..Optimism was assessed at baseline (t1) and cognition was measured every two years with up to five repeated assessments of cognition data over the 8‐year follow‐up period (t1; t2; t3; t4;… Continue reading The association between actor/partner #optimism and #cognitive functioning among older couples
Body #mass index, #diabetes, and the risk of #Parkinson’s disease
..A total of 33,443 individuals were diagnosed with PD during the follow‐up period (7.3 years). An increased risk of PD incidence was observed in the underweight group versus the normal group (adjusted hazard ratio: 1.28; 95% confidence interval: 1.21–1.36), whereas a decreased risk of PD incidence was observed (adjusted hazard ratio: 0.88; 95% confidence interval: 0.88–0.93)… Continue reading Body #mass index, #diabetes, and the risk of #Parkinson’s disease
Body #height in young adult men and risk of #dementia later in adult life
... A total of 666,333 men, 70,608 brothers, and 7388 twin brothers born 1939–1959 and examined at the conscript board were followed in Danish nationwide registers (1969–2016). Cox regression models were applied to analyze the association between body height and dementia. Within-brothers and within-twin pair analyses were conducted to explore the role of shared familial… Continue reading Body #height in young adult men and risk of #dementia later in adult life
Efficacy and Safety of #Lanabecestat for Treatment of Early and Mild #Alzheimer Disease
Does lanabecestat, a potent inhibitor of the beta-site amyloid precursor protein–cleaving enzyme 1 (BACE1), slow the progression of early Alzheimer disease (AD) and mild AD dementia?.. ..Among 1722 DAYBREAK-ALZ patients, the mean (SD) age was 72.3 (7.0) years, and 1023 of 1722 (59.4%) were women. Both studies were terminated early after futility analysis. There were… Continue reading Efficacy and Safety of #Lanabecestat for Treatment of Early and Mild #Alzheimer Disease
How #odor cues help to optimize #learning during sleep in a real life-setting
Effortless learning during sleep is everybody’s dream. Several studies found that presenting odor cues during learning and selectively during slow wave sleep increases learning success.. ..We (1) performed a field study of vocabulary-learning in a regular school setting, (2) stimulated with odor cues during the whole night without sleep monitoring, and (3) applied the odor… Continue reading How #odor cues help to optimize #learning during sleep in a real life-setting
Effects of #Caffeine and Acute Aerobic #Exercise on Working Memory and Caffeine Withdrawal
Studies show that a single bout of exercise confers cognitive benefits. However, many individuals use psychoactive substances such as caffeine to enhance cognitive performance.. The objectives of this study were to compare the effects of acute moderate intensity aerobic exercise to caffeine on working memory (WM) and caffeine withdrawal symptoms (CWS). In Phase I, non-caffeine… Continue reading Effects of #Caffeine and Acute Aerobic #Exercise on Working Memory and Caffeine Withdrawal
Five-Year Outcomes of Transcatheter or Surgical #Aortic-Valve Replacement
..At 5 years, there was no significant difference in the incidence of death from any cause or disabling stroke between the TAVR group and the surgery group (47.9% and 43.4%, respectively; hazard ratio, 1.09; 95% confidence interval [CI], 0.95 to 1.25; P=0.21). Results were similar for the transfemoral-access cohort (44.5% and 42.0%, respectively; hazard ratio,… Continue reading Five-Year Outcomes of Transcatheter or Surgical #Aortic-Valve Replacement
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