Background and Objectives: It has been suggested that higher triglyceride levels were associated with a lower risk of Alzheimer's disease. This study aimed to examine the association of triglycerides with dementia and cognition change in community-dwelling older adults.Methods: This prospective longitudinal study used data from the ASPREE randomized trial of adults aged ≥65 years without dementia or… Continue reading Association Between #Triglycerides and Risk of #Dementia in Community-Dwelling #Older Adults: A Prospective Cohort Study
Category: Neurology
#Proton pump inhibitors and #dementia: A nationwide population-based study
Proton pump inhibitors (PPIs) may increase dementia risk. However, it is currently unknown whether timing of exposure or age at dementia diagnosis influence the risk.METHODSWe assessed associations between cumulative PPI use and dementia at different ages in a nationwide Danish cohort of 1,983,785 individuals aged 60 to 75 years between 2000 and 2018.RESULTSDuring follow-up, there… Continue reading #Proton pump inhibitors and #dementia: A nationwide population-based study
#Sleeping Difficulties, #Sleep Duration, and Risk of #Hypertension in Women
Rates of poor sleep and hypertension are alarming worldwide. In this study, we investigate the association between sleeping difficulties and sleep duration with hypertension risk in women.METHODS:Sixty-six thousand one hundred twenty-two participants of the NHS2 (Nurses’ Health Study 2), who were free of hypertension at baseline (2001), were followed prospectively for 16 years and incident… Continue reading #Sleeping Difficulties, #Sleep Duration, and Risk of #Hypertension in Women
#Dementia;What you know about?
Dementia;What you know about?
Hot Topics: Is sleep deprivation more dangerous than many people realise?
Although sleep is an essential and important part of human life, sleep loss has become a widespread problem in today’s fast-paced society. The modern way of life frequently extols efficiency and the capacity to function with little sleep, yet the negative effects of sleep deprivation are much more severe than most people think. Maintaining physical,… Continue reading Hot Topics: Is sleep deprivation more dangerous than many people realise?
The Importance of Consistent Sleep Habits in Slowing Down the Aging Process
Consistent Sleep Habits Shown to Slow Down Aging Process, Study Finds A recent study conducted by researchers at Augusta University in the United States has revealed the significant impact of maintaining consistent sleep habits on overall health and aging. The findings suggest that a regular sleep routine not only benefits cognitive processes such as thinking… Continue reading The Importance of Consistent Sleep Habits in Slowing Down the Aging Process
Incidence of adverse #cardiovascular events in patients with #insomnia: A systematic review and meta-analysis of real-world data
Insomnia is a prevalent sleeping disorder associated with increasing cardiovascular (CV) mortality and morbidity. However, data incorporating recent clinical studies evaluating these outcomes is scarce. Hence, we aimed to investigate the association of insomnia with CV mortality, myocardial infarction (MI), all-cause mortality, and incidence of CV disease by conducting the first-ever meta-analysis of real-world data… Continue reading Incidence of adverse #cardiovascular events in patients with #insomnia: A systematic review and meta-analysis of real-world data
Effects of chronic #caffeine on patterns of #brain blood flow and behavior throughout the sleep–wake cycle in freely behaving mice
Caffeine has significant effects on neurovascular activity and behavior throughout the sleep–wake cycle. We used a minimally invasive microchip/video system to continuously record effects of caffeine in the drinking water of freely behaving mice. Chronic caffeine shifted both rest and active phases by up to 2 h relative to the light–dark cycle in a dose-dependent fashion.… Continue reading Effects of chronic #caffeine on patterns of #brain blood flow and behavior throughout the sleep–wake cycle in freely behaving mice
#Dementia Risk of Direct Oral Anticoagulants Versus Warfarin for Atrial #Fibrillation: Systematic Review and Meta-Analysis
BackgroundDirect-acting oral anticoagulants (DOACs) have demonstrated superior efficacy in preventing stroke and death compared with warfarin in patients with atrial fibrillation (AF), but their influence on dementia risk remains unclear.ObjectivesThe purpose of this study was to evaluate the relative risks of dementia in DOAC vs warfarin in patients with AF.MethodsAn electronic literature search was conducted… Continue reading #Dementia Risk of Direct Oral Anticoagulants Versus Warfarin for Atrial #Fibrillation: Systematic Review and Meta-Analysis