Antibiotic over prescription for upper respiratory tract infections (URTIs) in primary care exacerbates antimicrobial resistance. There is a need for effective alternatives to antibiotic prescribing. Honey is a lay remedy for URTIs, and has an emerging evidence base for its use. Honey has antimicrobial properties, and guidelines recommended honey for acute cough in children.. ..We… Continue reading Effectiveness of #honey for symptomatic relief in upper #respiratory tract infections: a systematic review and meta-analysis
Category: Infectivology
Clinical Course and Molecular Viral Shedding Among Asymptomatic and Symptomatic Patients With #SARS-CoV-2 Infection in a Community Treatment Center in the Republic of Korea
There is limited information about the clinical course and viral load in asymptomatic patients infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).. Epidemiologic, demographic, and laboratory data were collected and analyzed. Attending health care personnel carefully identified patients’ symptoms during isolation. The decision to release an individual from isolation was based on the results… Continue reading Clinical Course and Molecular Viral Shedding Among Asymptomatic and Symptomatic Patients With #SARS-CoV-2 Infection in a Community Treatment Center in the Republic of Korea
Association of acute myocardial #infarction with #influenza: A nationwide observational study
Influenza may precipitate cardiovascular disease, but influenza typically peaks in winter, coinciding with other triggers of myocardial infarction (MI) such as low air temperature, high wind velocity, low atmospheric pressure, and short sunshine duration.. Weekly laboratory-confirmed influenza case reports were obtained from the Public Health Agency of Sweden from 2009 to 2016 and merged with… Continue reading Association of acute myocardial #infarction with #influenza: A nationwide observational study
Reducing #Antibiotic Prescribing in Primary Care for #Respiratory Illness
One-third of outpatient antibiotic prescriptions for pediatric acute respiratory tract infections (ARTIs) are inappropriate. We evaluated a distance learning program’s effectiveness for reducing outpatient antibiotic prescribing for ARTI visits.. In this stepped-wedge clinical trial run from November 2015 to June 2018, we randomly assigned 19 pediatric practices belonging to the Pediatric Research in Office Settings… Continue reading Reducing #Antibiotic Prescribing in Primary Care for #Respiratory Illness
Mandated Bacillus Calmette-Guérin (#BCG) vaccination predicts flattened curves for the spread of #COVID-19
Bacillus Calmette-Guérin (BCG) vaccination may reduce the risk of a range of infectious diseases, and if so, it could protect against coronavirus disease 2019 (COVID-19). Here, we compared countries that mandated BCG vaccination until at least 2000 with countries that did not. To minimize any systematic effects of reporting biases, we analyzed the rate of… Continue reading Mandated Bacillus Calmette-Guérin (#BCG) vaccination predicts flattened curves for the spread of #COVID-19
Selective and cross-reactive #SARS-CoV-2 #T cell epitopes in unexposed humans
Many unknowns exist about human immune responses to the SARS-CoV-2 virus. SARS-CoV-2 reactive CD4+ T cells have been reported in unexposed individuals, suggesting pre-existing cross-reactive T cell memory in 20-50% of people. However, the source of those T cells has been speculative. Using human blood samples derived before the SARS-CoV-2 virus was discovered in 2019,… Continue reading Selective and cross-reactive #SARS-CoV-2 #T cell epitopes in unexposed humans
Association of triage #hypothermia with in-hospital mortality among patients in the emergency department with suspected #sepsis
To identify if triage hypothermia (<36.0 °C) among emergency department (ED) encounters with sepsis are independently associated with mortality.. ..Of 1.2 billion ED encounters (95% confidence interval [CI] 1.0–1.3 billion), 3.1 million (95% CI 2.7–3.5 million) met the explicit sepsis definition; 7.4% (95% CI 75.2–9.7%) had triage hypothermia. The adjusted odds ratio (aOR) for hypothermia… Continue reading Association of triage #hypothermia with in-hospital mortality among patients in the emergency department with suspected #sepsis
Association of Nonoperative Management Using Antibiotic Therapy vs Laparoscopic #Appendectomy With Treatment Success and Disability Days in Children With Uncomplicated #Appendicitis
Nonoperative management with antibiotics alone has the potential to treat uncomplicated pediatric appendicitis with fewer disability days than surgery.. ..Patient and family selection of nonoperative management with antibiotics alone (nonoperative group, n = 370) or urgent (≤12 hours of admission) laparoscopic appendectomy (surgery group, n = 698). Main Outcomes and Measures The 2 primary outcomes assessed at 1 year… Continue reading Association of Nonoperative Management Using Antibiotic Therapy vs Laparoscopic #Appendectomy With Treatment Success and Disability Days in Children With Uncomplicated #Appendicitis
Outcomes of Cardiovascular Magnetic Resonance Imaging in Patients Recently Recovered From Coronavirus Disease 2019 (COVID-19)
Coronavirus disease 2019 (COVID-19) continues to cause considerable morbidity and mortality worldwide. Case reports of hospitalized patients suggest that COVID-19 prominently affects the cardiovascular system, but the overall impact remains unknown. ..Of the 100 included patients, 53 (53%) were male, and the median (interquartile range [IQR]) age was 49 (45-53) years. The median (IQR) time… Continue reading Outcomes of Cardiovascular Magnetic Resonance Imaging in Patients Recently Recovered From Coronavirus Disease 2019 (COVID-19)
2 Medical News 