Use of aspirin and other non-steroidal anti-inflammatory drugs (NSAIDs) has been hypothesized to be associated with reduced risk of breast cancer; however, results of epidemiological studies have been mixed. Few studies have investigated these associations among African American women.. To assess the relation of aspirin use to risk of breast cancer in African American women,… Continue reading #Aspirin use and risk of #breast cancer in African American women
Category: Gynaecology
#Obesity Has a Stronger Relationship with Colorectal #Cancer in Postmenopausal Women Than Premenopausal Women
Background: To examine the relationship between obesity measured by waist circumference (WC) and body mass index (BMI) and the incidence of colorectal cancer (CRC) in premenopausal and postmenopausal women. Methods: A total of 1,418,180 premenopausal and 4,854,187 postmenopausal women without cancer at baseline and aged over 40 were identified using the Korean National Health Insurance… Continue reading #Obesity Has a Stronger Relationship with Colorectal #Cancer in Postmenopausal Women Than Premenopausal Women
Association of #Menopausal Hormone Therapy With Breast #Cancer Incidence and Mortality During Long-term Follow-up of the Women’s Health Initiative Randomized Clinical Trials
In the trial involving 16 608 women with a uterus, 8506 were randomized to receive 0.625 mg/d of conjugated equine estrogen (CEE) plus 2.5 mg/d of medroxyprogesterone acetate (MPA) and 8102, placebo. In the trial involving 10 739 women with prior hysterectomy, 5310 were randomized to receive 0.625 mg/d of CEE alone and 5429, placebo. The CEE-plus-MPA… Continue reading Association of #Menopausal Hormone Therapy With Breast #Cancer Incidence and Mortality During Long-term Follow-up of the Women’s Health Initiative Randomized Clinical Trials
The Prevalence of Thyroid Dysfunction and Autoimmunity in Women With History of Miscarriage or Subfertility
..Thyroid function and thyroid peroxidase antibody (TPOAb) data were available for 19213 and 19237 women, respectively. The prevalence of abnormal thyroid function was 4.8% (95% CI, 4.5-5.1); euthyroidism was defined as levels of thyroid-stimulating hormone (TSH) of 0.44 to 4.50 mIU/L and free thyroxine (fT4) of 10 to 21 pmol/L. Overt hypothyroidism (TSH > 4.50… Continue reading The Prevalence of Thyroid Dysfunction and Autoimmunity in Women With History of Miscarriage or Subfertility
Association of Living in a Food Desert With Pregnancy Morbidity
To evaluate whether women living in areas deemed food deserts had higher rates of pregnancy morbidity, specifically preeclampsia, gestational hypertension, gestational diabetes, prelabor rupture of membranes, preterm labor, than women who did not live in food deserts at the time of their pregnancy and delivery.. This was a retrospective observational study in which we reviewed… Continue reading Association of Living in a Food Desert With Pregnancy Morbidity
Oral #fluconazole use in the first trimester and risk of congenital #malformations: population based cohort study
..The study cohort of 1 969 954 pregnancies included 37 650 (1.9%) pregnancies exposed to oral fluconazole and 82 090 (4.2%) pregnancies exposed to topical azoles during the first trimester. The risk of musculoskeletal malformations was 52.1 (95% confidence interval 44.8 to 59.3) per 10 000 pregnancies exposed to fluconazole versus 37.3 (33.1 to 41.4) per 10 000 pregnancies exposed to… Continue reading Oral #fluconazole use in the first trimester and risk of congenital #malformations: population based cohort study
Regular Mindful #Yoga Practice as a Method to Improve Androgen Levels in Women With Polycystic #Ovary Syndrome: A Randomized, Controlled Trial
Holistic approaches are needed to complement existing therapies for polycystic ovary syndrome (PCOS), a common disorder affecting the health of reproductive-aged females.. ..epiandrosterone, androstenedione, body mass index, waist-to-hip ratio, fasting blood glucose and insulin levels, and anxiety and depression scores. Results: Twenty-two women completed the 3-month intervention period, 13 in the mindful yoga group and… Continue reading Regular Mindful #Yoga Practice as a Method to Improve Androgen Levels in Women With Polycystic #Ovary Syndrome: A Randomized, Controlled Trial
Mitochondrial and redox dysfunction in post-#menopause as risk factor of neurodegenerative disease: a pilot study testing the role of a validated Japanese functional food.
During the menopause women may experience increased oxidative stress and decreased antioxidant capacity and, together with the decline of neurosteroids, this represents a risk factor for Alzheimer's disease. The aim of the present study was to test a functional food (FPP-ORI, Osato Research Institute, Gifu, Japan) on redox and mitochondrial efficiency in post-menopausal women. The… Continue reading Mitochondrial and redox dysfunction in post-#menopause as risk factor of neurodegenerative disease: a pilot study testing the role of a validated Japanese functional food.
Maternal #Hypertensive Pregnancy Disorders and #Mental Disorders in Children
The associations of maternal hypertensive pregnancy disorders with offspring mental disorders remain unclear. We examined whether maternal hypertensive disorders and maximum blood pressure during pregnancy predict offspring childhood mental disorders, whether the associations are independent of maternal and paternal mental disorders and paternal hypertensive disorders, independent of or additive with maternal early pregnancy overweight/obesity and… Continue reading Maternal #Hypertensive Pregnancy Disorders and #Mental Disorders in Children
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