AbstractCoffee is one of the most widely consumed beverages globally, with over 60% of Americans drinking it daily. This review examines coffee’s multifaceted impact on health and well-being, drawing on decades of research. Overall, the consensus is that moderate coffee intake is more beneficial than harmful across a wide range of health outcomes. Numerous large-scale,… Continue reading #Coffee ’s Impact on #Health and #Well-Being
Category: Diet
#Ultraprocessed or minimally processed diets following healthy dietary guidelines on #weight and cardiometabolic health: a randomized, crossover trial
Ultraprocessed food (UPF) consumption is associated with noncommunicable disease risk, yet no trial has assessed its health impact within the context of national dietary guidelines. In a 2 × 2 crossover randomized controlled feeding trial, 55 adults in England (body mass index ≥25 to <40 kg m−2, habitual UPF intake ≥50% kcal day−1) were provided with two 8-week ad libitum… Continue reading #Ultraprocessed or minimally processed diets following healthy dietary guidelines on #weight and cardiometabolic health: a randomized, crossover trial
The impact of #almond supplementation on #oxidative stress biomarkers: a systematic review and meta-analysis of randomized control trials
Oxidative stress, an imbalance between reactive oxygen species and antioxidants, contributes to chronic diseases. Almonds, rich in vitamin E, polyphenols, and monounsaturated fats, exhibit antioxidant potential, though their overall effects on oxidative biomarkers are unclear. This systematic review and meta-analysis evaluate almond supplementation’s impact on these biomarkers in adults. Following PRISMA guidelines, PubMed, Scopus, and… Continue reading The impact of #almond supplementation on #oxidative stress biomarkers: a systematic review and meta-analysis of randomized control trials
#Cruciferous #vegetables intake and risk of #colon #cancer: a dose–response meta-analysis
Colon cancer (CC) is the third most diagnosed malignancy and second leading cause of cancer mortality globally, with ~ 1.9 million new cases and 903,859 deaths annually (Bray et al. in CA Cancer J Clin 68(6):394–424, 2018). Diet represents a key modifiable risk factor for CC pathogenesis (Herr and Buchler in Cancer Treat Rev 36:377–383, 2010). Cruciferous… Continue reading #Cruciferous #vegetables intake and risk of #colon #cancer: a dose–response meta-analysis
The Effects of the #Mediterranean Diet on #Health and Gut #Microbiota
The Mediterranean Diet (MD) is plant-based and consists of multiple daily portions of vegetables, fruit, cereals, and olive oil. Although there are challenges with isolating the MD from the typical Mediterranean lifestyle and culture (including prolonged ‘social’ meals and siestas), much evidence supports the health benefits of the MD that include improved longevity, reduced metabolic… Continue reading The Effects of the #Mediterranean Diet on #Health and Gut #Microbiota
Total and specific #potato intake and risk of type 2 #diabetes: results from three US cohort studies and a substitution meta-analysis of prospective cohorts
Objectives To investigate the associations between total and individual potato intake and risk of type 2 diabetes (T2D), estimate the effect on T2D risk of replacing potatoes with whole grains and other major carbohydrate sources, and conduct a dose-response and substitution meta-analysis of prospective cohort studies.Design Prospective cohort study and dose-response meta-analysis of prospective cohort… Continue reading Total and specific #potato intake and risk of type 2 #diabetes: results from three US cohort studies and a substitution meta-analysis of prospective cohorts
#Dietary patterns and accelerated multimorbidity in #older adults
Diet could influence disease development and shape multimorbidity trajectories. Here we examined how four dietary patterns relate to 15-year multimorbidity accumulation in 2,473 community-dwelling older adults from the Swedish SNAC-K cohort. Multimorbidity was operationalized as the total number of chronic conditions and grouped into three organ systems. Higher adherence to the Mediterranean-DASH Diet Intervention for… Continue reading #Dietary patterns and accelerated multimorbidity in #older adults
#Sucralose consumption ablates #cancer immunotherapy response through #microbiome disruption
Gut microbiota composition is directly associated with response to immunotherapies in cancer. How the diet impacts the gut microbiota and downstream immune responses to cancer remains unclear. Here, we show that consumption of a common non-nutritive sweetener, sucralose, modifies microbiome composition, restricts T cell metabolism and function, and limits immunotherapy response in preclinical models of… Continue reading #Sucralose consumption ablates #cancer immunotherapy response through #microbiome disruption
Association between ultra-processed #food consumption and #lung #cancer risk: a population-based cohort study
Background The evidence on associations between ultra-processed foods (UPF) and lung cancer risk is limited and inconsistent.Research question Are UPF associated with an increased risk of lung cancer, non-small cell lung cancer (NSCLC) and small cell lung cancer (SCLC)?Methods Data of participants in this study were collected from the Prostate, Lung, Colorectal and Ovarian (PLCO)… Continue reading Association between ultra-processed #food consumption and #lung #cancer risk: a population-based cohort study