Use of ancient #grains for the management of #diabetes mellitus: A systematic review and meta-analysis

Highlights•Oats, brown rice, and millet improve health outcomes in diabetes mellitus type 2.•The most prevalent grains tested in trials included oats, brown rice, and buckwheat.•The most outcomes studied in diabetes were related to cardiovascular risk factors.AimsA systematic review and meta-analysis of published randomized controlled trials was conducted to collate evidence from studies implementing ancient grains… Continue reading Use of ancient #grains for the management of #diabetes mellitus: A systematic review and meta-analysis

Consumption of #Olive Oil and Diet Quality and Risk of #Dementia-Related Death

Question  Is the long-term consumption of olive oil associated with dementia-related death risk? Findings  In a prospective cohort study of 92 383 adults observed over 28 years, the consumption of more than 7 g/d of olive oil was associated with a 28% lower risk of dementia-related death compared with never or rarely consuming olive oil, irrespective of diet… Continue reading Consumption of #Olive Oil and Diet Quality and Risk of #Dementia-Related Death

Associations of #dietary patterns with #brain health from behavioral, neuroimaging, biochemical and genetic analyses

Food preferences significantly influence dietary choices, yet understanding natural dietary patterns in populations remains limited. Here we identifiy four dietary subtypes by applying data-driven approaches to food-liking data from 181,990 UK Biobank participants: ‘starch-free or reduced-starch’ (subtype 1), ‘vegetarian’ (subtype 2), ‘high protein and low fiber’ (subtype 3) and ‘balanced’ (subtype 4). These subtypes varied… Continue reading Associations of #dietary patterns with #brain health from behavioral, neuroimaging, biochemical and genetic analyses

One #Avocado per Day as Part of Usual Intake Improves #Diet Quality: Exploratory Results from a Randomized Controlled Trial

Few clinical trials have evaluated diet quality change as a predictor of intervention effectiveness.ObjectivesThe aim of this study was to examine changes in the Healthy Eating Index (HEI)-2015 after a food-based intervention, and assess the associations between HEI-2015 change and intervention effects on cardiometabolic risk–related outcomes.MethodsThe Habitual Diet and Avocado Trial was a 26-wk, multicenter,… Continue reading One #Avocado per Day as Part of Usual Intake Improves #Diet Quality: Exploratory Results from a Randomized Controlled Trial

Opposing diet, #microbiome, and metabolite mechanisms regulate inflammatory #bowel disease in a genetically susceptible host

Highlights•Dietary fiber-deprived gut microbiota elicits lethal colitis in Il10−/− mice•Mucolytic gut bacteria weaken mucus and drive inflammatory immune responses•Alterations in bacterial IgA coating and increased NK cells precede inflammation•Exclusive enteral nutrition promotes bacterial isobutyrate, reducing inflammationSummaryInflammatory bowel diseases (IBDs) are chronic conditions characterized by periods of spontaneous intestinal inflammation and are increasing in industrialized populations. Combined with… Continue reading Opposing diet, #microbiome, and metabolite mechanisms regulate inflammatory #bowel disease in a genetically susceptible host

Apple cider # for weight management in Lebanese adolescents and young adults with #overweight and obesity: a randomised, double-blind, placebo-controlled study

Background and aims Obesity and overweight have become significant health concerns worldwide, leading to an increased interest in finding natural remedies for weight reduction. One such remedy that has gained popularity is apple cider vinegar (ACV).Objective To investigate the effects of ACV consumption on weight, blood glucose, triglyceride and cholesterol levels in a sample of the Lebanese… Continue reading Apple cider # for weight management in Lebanese adolescents and young adults with #overweight and obesity: a randomised, double-blind, placebo-controlled study

#Diet, Pace of Biological #Aging, and Risk of #Dementia in the Framingham Heart Study

AbstractObjectivePeople who eat healthier diets are less likely to develop dementia, but the biological mechanism of this protection is not well understood. We tested the hypothesis that healthy diet protects against dementia because it slows the pace of biological aging.MethodsWe analyzed Framingham Offspring Cohort data. We included participants ≥60 years-old, free of dementia and having dietary,… Continue reading #Diet, Pace of Biological #Aging, and Risk of #Dementia in the Framingham Heart Study

Dietary #Niacin Intake and Mortality Among Individuals With Nonalcoholic #Fatty #Liver Disease

Importance  Evidence regarding the effect of dietary niacin intake on the risk of mortality among patients with nonalcoholic fatty liver disease (NAFLD) is scarce.Objective  To examine the association of dietary niacin intake with all-cause mortality and cardiovascular disease (CVD) mortality among individuals with NAFLD.Design, Setting, and Participants  This cohort study used data from the National Health and Nutrition… Continue reading Dietary #Niacin Intake and Mortality Among Individuals With Nonalcoholic #Fatty #Liver Disease

Effect of #Ergocalciferol on β-Cell Function in New-Onset Type 1 #Diabetes A Secondary Analysis of a Randomized Clinical Trial

IntroductionApproximately 30% to 50% residual β-cell function may remain at the time of type 1 diabetes (T1D) diagnosis, and this may persist for months or years.1,2 A prolonged partial remission (PR) phase of T1D leads to improved glycemic control and decreased long-term complications.1 We previously reported1 that ergocalciferol significantly decreased circulating tumor necrosis factor (TNF)-α and temporal trends… Continue reading Effect of #Ergocalciferol on β-Cell Function in New-Onset Type 1 #Diabetes A Secondary Analysis of a Randomized Clinical Trial