Evaluation of the Safety and Effectiveness of Nutritional Supplements for Treating Hair LossA Systematic Review

Importance  Despite the widespread use of nutritional supplements and dietary interventions for treating hair loss, the safety and effectiveness of available products remain unclear.Objective  To evaluate and compile the findings of all dietary and nutritional interventions for treatment of hair loss among individuals without a known baseline nutritional deficiency.Evidence Review  The MEDLINE, Embase, and CINAHL databases were searched… Continue reading Evaluation of the Safety and Effectiveness of Nutritional Supplements for Treating Hair LossA Systematic Review

Oral Herpes Zoster Infection Following COVID-19 Vaccination: A Report of Five Cases

Recently, two cases of oral herpes zoster (HZ) following COVID-19 vaccines were reported. It was suggested that COVID-19 vaccine-related oral HZ cases might be missed or misdiagnosed as stomatitis or isolated oral herpes. In this report, five cases of oral HZ following COVID-19 vaccinations are presented. Four cases were observed on the hard palate (V2),… Continue reading Oral Herpes Zoster Infection Following COVID-19 Vaccination: A Report of Five Cases

Alopecia areata following COVID-19 vaccination: vaccine-induced autoimmunity?

Dear Editor, We report a case of an 80-year-old man who came to our attention for a rapidly progressive loss of facial hair 7 days after the administration of the first dose of the BNT162b2 vaccine, an mRNA vaccine against SARS-CoV-2. He had no personal or family history of alopecia or autoimmunity. Before the vaccination, a… Continue reading Alopecia areata following COVID-19 vaccination: vaccine-induced autoimmunity?

Eczema is a shared risk factor for anxiety and depression: A meta-analysis and systematic review

Globally, anxiety and depression are the most common psychiatric disorders that add large burdens to individuals and society; however, the mechanisms underlying these disorders are unclear. Several studies have found that eczema is a shared risk factor for both these conditions. We identified and evaluated eligible observational studies from EMBASE and PubMed. In total, 20… Continue reading Eczema is a shared risk factor for anxiety and depression: A meta-analysis and systematic review

Two Phase 3 Trials of Baricitinib for Alopecia Areata

BACKGROUNDAlopecia areata is an autoimmune condition characterized by rapid hair loss in the scalp, eyebrows, and eyelashes, for which treatments are limited. Baricitinib, an oral, selective, reversible inhibitor of Janus kinases 1 and 2, may interrupt cytokine signaling implicated in the pathogenesis of alopecia areata. METHODSWe conducted two randomized, placebo-controlled, phase 3 trials (BRAVE-AA1 and… Continue reading Two Phase 3 Trials of Baricitinib for Alopecia Areata

New-onset of vitiligo in a child following COVID-19 vaccination

Since January 2020, the ongoing COVID-19 pandemic has been a global health emergency. Vaccination is a critical measure for containing the spread of COVID-19. At the end of 2020, several vaccines became available. Multiple adverse events (AEs) have been reported with all the available COVID-19 vaccines. This report describes a case of vitiligo in a… Continue reading New-onset of vitiligo in a child following COVID-19 vaccination

Association of Cardiac Biomarkers with Cardiovascular Outcomes in Patients with Psoriatic Arthritis and Psoriasis: A Longitudinal Cohort Study

In patients with psoriatic disease (PsD), we determined whether cardiac troponin I (cTnI) and N-terminal pro-brain-type natriuretic peptide (NT-proBNP) were associated with carotid plaque burden and the development of cardiovascular (CV) events independent of the Framingham Risk Score (FRS). MethodsAmong 1,000 patients with PsD, carotid total plaque area (TPA) was measured in 358 participants at… Continue reading Association of Cardiac Biomarkers with Cardiovascular Outcomes in Patients with Psoriatic Arthritis and Psoriasis: A Longitudinal Cohort Study

Efficacy of botulinum toxin A injection in the treatment of androgenic alopecia: A Comparative Controlled Study

IntroductionScalp injection with mesotherapy (LC cell hair essence) helps in anchoring hair follicles and might have good therapeutic efficacy and lower side effects than Botox in the treatment of androgenetic alopecia (AGA). ObjectiveTo assess the trichoscopy and the clinical therapeutic response of LC hair essence serum injection vs. botulinum toxin (A) injection in the treatment… Continue reading Efficacy of botulinum toxin A injection in the treatment of androgenic alopecia: A Comparative Controlled Study

How effective are interventions to reduce Staphylococcus aureus in eczema?

Key messagesEczema is commonly colonized by Staphylococcus aureus so some advocate antibiotics or dilute bleach baths. This Cochrane review evaluated trials of anti-staph treatments in people with infected or uninfected eczema. From 41 trials (1753 participants), there was little evidence that these interventions impact eczema symptoms. ... 2.7 Authors’ conclusionsWe found insufficient evidence on the… Continue reading How effective are interventions to reduce Staphylococcus aureus in eczema?