The oral #microbiome in early #rheumatoid arthritis patients and individuals at risk differs from healthy controls

It has been suggested that rheumatoid arthritis (RA) may originate at the oral mucosa. Our aim was to assess the oral microbiome and the periodontal condition in patients with early rheumatoid arthritis (ERA) and individuals at risk of RA. MethodsThree groups were recruited (50 participants each): (1) ERA patients (2010 ACR/EULAR criteria), (2) at‐risk individuals …

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Association between #periodontitis and severity of #COVID‐19 infection: A case–control study

COVID‐19 is associated with an exacerbated inflammatory response that can result in fatal outcomes. Systemic inflammation is also a main characteristic of periodontitis. Therefore, we investigated the association of periodontitis with COVID‐19 complications. Materials and MethodsA case–control study was performed using the national electronic health records of the State of Qatar between February and July …

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Elevated #Coronary Artery Calcium scores are associated with #tooth loss

This study explores the association between Coronary Artery Calcium (CAC) scores and dental pathology such as missing teeth, the (peri-apical) health status and restoration grade of the teeth, and the grade of alveolar bone loss seen on a dental panoramic radiograph (Orthopantomograph–OPG).. ..212 patients were included. We found a statistically significant association between the number …

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#Periodontal Inflammation Primes the Systemic Innate #Immune Response

The presence of periodontal diseases (PDs) often strongly correlates with other severe chronic inflammatory conditions, including cardiovascular disease, diabetes, and arthritis. However, the mechanisms through which these diseases interact are unclear. In PD, tissue and bone destruction in the mouth is driven by elevated recruitment of polymorphonuclear neutrophils (PMNs), which are primed and recruited from …

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#Periodontitis increases the risk of respiratory disease mortality in older patients

Evidence for an association between periodontitis and respiratory disease in the older patients is limited.. ..We found that periodontitis was associated with total respiratory disease mortality. Compared with healthy participants, the hazards ratio and 95% confidence interval for total respiratory disease mortality in patients with severe periodontitis was 2.72(1.04,7.11) after adjusting for relevant confounding variables. …

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