Incidence curve analyses showed progressively higher 30-year cardiovascular disease event-rates for increasing non-HDL cholesterol categories (from 7·7% for non-HDL cholesterol <2·6 mmol/L to 33·7% for ≥5·7 mmol/L in women and from 12·8% to 43·6% in men; p<0·0001). Multivariable adjusted Cox models with non-HDL cholesterol lower than 2·6 mmol/L as reference showed an increase in the… Continue reading Application of non-HDL #cholesterol for population-based cardiovascular risk stratification: results from the Multinational #Cardiovascular Risk Consortium
Category: Cardiology
Improved #oral hygiene care is associated with decreased risk of occurrence for atrial #fibrillation and heart #failure: A nationwide population-based cohort study
Poor oral hygiene can provoke transient bacteremia and systemic inflammation, a mediator of atrial fibrillation and heart failure.. .. In multivariate analysis after adjusting age, sex, socioeconomic status, regular exercise, alcohol consumption, body mass index, hypertension, diabetes, dyslipidemia, current smoking, renal disease, history of cancer, systolic blood pressure, blood and urine laboratory findings, frequent tooth… Continue reading Improved #oral hygiene care is associated with decreased risk of occurrence for atrial #fibrillation and heart #failure: A nationwide population-based cohort study
Effectiveness of a Brief Self-determination Theory–Based Smoking Cessation Intervention for Smokers at Emergency Departments in Hong Kong
Clinicians have an opportunity to provide #smoking cessation interventions to smokers who present to emergency departments (EDs). The effectiveness of a brief intervention based on self-determination theory for smoking cessation is uncertain. ..The intervention group received brief advice (about 1 minute) and could choose their own quit schedules (immediate or progressive) ..Compared with the control… Continue reading Effectiveness of a Brief Self-determination Theory–Based Smoking Cessation Intervention for Smokers at Emergency Departments in Hong Kong
#Waist Circumference Change is Associated with Blood #pressure Change Independent of BMI Change
This study aimed to understand how an increase in abdominal adiposity relative to overall adiposity is associated with blood pressure (BP) change.. ..Each 10‐cm annual WC gain in men and women was associated with a 0.98‐mm Hg (95% CI: 0.61‐1.35) and a 0.97‐mm Hg (95% CI: 0.62‐1.32) annual increase in systolic blood pressure and a… Continue reading #Waist Circumference Change is Associated with Blood #pressure Change Independent of BMI Change
#Cognitive Decline Over Time in Patients With Systolic #Heart Failure Insights From WARCEF
This study sought to characterize cognitive decline (CD) over time and its predictors in patients with systolic heart failure (HF) ..In logistic regression, CD was independently associated with higher baseline MMSE scores (odds ratio [OR]: 1.13; 95% confidence interval [CI]: 1.07 to 1.20]; p < 0.001), older age (OR: 1.37; 95% CI: 1.24 to 1.50;… Continue reading #Cognitive Decline Over Time in Patients With Systolic #Heart Failure Insights From WARCEF
#Dapagliflozin in Patients with Heart Failure and Reduced #Ejection Fraction
In patients with type 2 diabetes, inhibitors of sodium–glucose cotransporter 2 (SGLT2) reduce the risk of a first hospitalization for heart failure, possibly through glucose-independent mechanisms.. A first worsening heart failure event occurred in 237 patients (10.0%) in the dapagliflozin group and in 326 patients (13.7%) in the placebo group (hazard ratio, 0.70; 95% CI,… Continue reading #Dapagliflozin in Patients with Heart Failure and Reduced #Ejection Fraction
Altered Risk for #cardiovascular Events With Changes in the #Metabolic Syndrome Status: A Nationwide Population-Based Study of Approximately 10 Million Persons
Population-scale evidence for the association between dynamic changes in metabolic syndrome (MetS) status and alterations in the risk for major adverse cardiovascular events (MACE) is lacking ..At a median follow-up of 3.54 years, the MetS-recovery group (incidence rate, 4.55 per 1000 person-years) had a significantly lower MACE risk (adjusted IRR, 0.85 [95% CI, 0.83 to… Continue reading Altered Risk for #cardiovascular Events With Changes in the #Metabolic Syndrome Status: A Nationwide Population-Based Study of Approximately 10 Million Persons
Association of #troponin level and age with #mortality in 250 000 patients: cohort study across five UK acute care centres
.. A positive troponin result (that is, higher than the upper limit of normal) signified a 3.2 higher mortality hazard (95% confidence interval 3.1 to 3.2) over three years. Mortality varied noticeably with age, with a hazard ratio of 10.6 (8.5 to 13.3) in 18-29 year olds and 1.5 (1.4 to 1.6) in those older… Continue reading Association of #troponin level and age with #mortality in 250 000 patients: cohort study across five UK acute care centres
Effect of Standard vs Intensive Blood #Pressure Control on the Risk of Recurrent #Stroke
The Systolic Blood Pressure Intervention Trial (SPRINT) demonstrated that a systolic blood pressure (BP) target less than 120 mm Hg was superior to less than 140 mm Hg for preventing vascular events. This trial excluded patients with prior stroke; therefore, the ideal BP target for secondary stroke prevention remains unknown. ..Throughout the overall follow-up period,… Continue reading Effect of Standard vs Intensive Blood #Pressure Control on the Risk of Recurrent #Stroke
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