Background: Meta analyses report beneficial effects of coffee intake on incident cardiovascular outcomes, however earlier studies are limited by smaller sample sizes. The aim was to evaluate associations between coffee intake and incident arrhythmia, CVD, and mortality, utilising the UK BiobankMethods: The UK Biobank is a large prospective cohort with outcomes measured >10 years. Coffee… Continue reading 1056-05 – EFFECTS OF HABITUAL COFFEE CONSUMPTION ON INCIDENT CARDIOVASCULAR DISEASE, ARRHYTHMIA, AND MORTALITY: FINDINGS FROM UK BIOBANK
Category: Cardiology
Association of Habitual Alcohol Intake With Risk of Cardiovascular Disease
Importance Observational studies have consistently proposed cardiovascular benefits associated with light alcohol consumption, while recent genetic analyses (ie, mendelian randomization studies) have suggested a possible causal link between alcohol intake and increased risk of cardiovascular disease. However, traditional approaches to genetic epidemiology assume a linear association and thus have not fully evaluated dose-response estimates of… Continue reading Association of Habitual Alcohol Intake With Risk of Cardiovascular Disease
Light exposure during sleep impairs cardiometabolic function
SignificanceAmbient nighttime light exposure is implicated as a risk factor for adverse health outcomes, including cardiometabolic disease. However, the effects of nighttime light exposure during sleep on cardiometabolic outcomes and the related mechanisms are unclear. This laboratory study shows that, in healthy adults, one night of moderate (100 lx) light exposure during sleep increases nighttime… Continue reading Light exposure during sleep impairs cardiometabolic function
Analysis of the SYSDIET Healthy Nordic Diet randomized trial based on metabolic profiling reveal beneficial effects on glucose metabolism and blood lipids
Background & aimsIntake assessment in multicenter trials is challenging, yet important for accurate outcome evaluation. The present study aimed to characterize a multicenter randomized controlled trial with a healthy Nordic diet (HND) compared to a Control diet (CD) by plasma and urine metabolic profiles and to associate them with cardiometabolic markers. MethodsDuring 18–24 weeks of… Continue reading Analysis of the SYSDIET Healthy Nordic Diet randomized trial based on metabolic profiling reveal beneficial effects on glucose metabolism and blood lipids
BNT162b2 Vaccine-Associated Myo/Pericarditis in Adolescents: A Stratified Risk-Benefit Analysis
BackgroundMale patients ages 12–17 years have an elevated risk of mRNA vaccination-associated myo/pericarditis. A risk-benefit analysis of first and second doses of mRNA vaccination in adolescent boys by health status and history of SARS-CoV-2 infection has not been performed. MethodsUsing the Vaccine Adverse Event Reporting System (VAERS), we identified BNT162b2 [Pfizer-BioNTech] myo/pericarditis occurrence according to… Continue reading BNT162b2 Vaccine-Associated Myo/Pericarditis in Adolescents: A Stratified Risk-Benefit Analysis
Association of Cardiac Biomarkers with Cardiovascular Outcomes in Patients with Psoriatic Arthritis and Psoriasis: A Longitudinal Cohort Study
In patients with psoriatic disease (PsD), we determined whether cardiac troponin I (cTnI) and N-terminal pro-brain-type natriuretic peptide (NT-proBNP) were associated with carotid plaque burden and the development of cardiovascular (CV) events independent of the Framingham Risk Score (FRS). MethodsAmong 1,000 patients with PsD, carotid total plaque area (TPA) was measured in 358 participants at… Continue reading Association of Cardiac Biomarkers with Cardiovascular Outcomes in Patients with Psoriatic Arthritis and Psoriasis: A Longitudinal Cohort Study
VTE Prophylaxis in Critically Ill AdultsA Systematic Review and Network Meta-analysis
BackgroundCritically ill adults are at increased risk of VTE, including DVT, and pulmonary embolism. Various agents exist for venous thromboprophylaxis in this population. Research QuestionWhat is the comparative efficacy and safety of prophylaxis agents for prevention of VTE in critically ill adults?Study Design and MethodsSystematic review and network meta-analysis of randomized clinical trials (RCTs) evaluating… Continue reading VTE Prophylaxis in Critically Ill AdultsA Systematic Review and Network Meta-analysis
Muscle-strengthening activities are associated with lower risk and mortality in major non-communicable diseases: a systematic review and meta-analysis of cohort studies
Objective To quantify the associations between muscle-strengthening activities and the risk of non-communicable diseases and mortality in adults independent of aerobic activities. Design Systematic review and meta-analysis of prospective cohort studies. Data sources MEDLINE and Embase were searched from inception to June 2021 and the reference lists of all related articles were reviewed. Eligibility criteria… Continue reading Muscle-strengthening activities are associated with lower risk and mortality in major non-communicable diseases: a systematic review and meta-analysis of cohort studies
Sodium-containing acetaminophen and cardiovascular outcomes in individuals with and without hypertension
AimsPrevious studies have found high sodium intake to be associated with increased risks of cardiovascular disease (CVD) and all-cause mortality among individuals with hypertension; findings on the effect of intake among individuals without hypertension have been equivocal. We aimed to compare the risks of incident CVD and all-cause mortality among initiators of sodium-containing acetaminophen with… Continue reading Sodium-containing acetaminophen and cardiovascular outcomes in individuals with and without hypertension
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